Practical aspects of the temperature dependence of the activity of uncoated and coated fused-silica columns in gas chromatography

1988 ◽  
Vol 25 (10) ◽  
pp. 899-902 ◽  
Author(s):  
H. F. Yin ◽  
A. J. Huang ◽  
Y. L. Sun
Keyword(s):  
Gas Chromatography ◽  
Temperature Dependence ◽  
Fused Silica

Determination of volatile alcohols and acetone in serum by non-polar capillary gas chromatography after direct sample injection.

1984 ◽  
Vol 30 (10) ◽  
pp. 1672-1674 ◽  
Author(s):  
N B Smith
Keyword(s):  
Gas Chromatography ◽  
Capillary Gas Chromatography ◽  
Capillary Column ◽  
Internal Standard ◽  
Fused Silica ◽  
Gas Chromatograph ◽  
Ionization Detector ◽  
Flame Ionization ◽  
Split Ratio

Abstract In this method for detection and quantification of volatile alcohols by capillary gas chromatography, the serum sample is deproteinized, then directly injected into the gas chromatograph with 1-propanol as the internal standard. The capillary column is a 30-m bonded methylsilicone-coated, fused-silica column. With helium as the carrier gas, the injector inlet is set at a split ratio of 1/30 and the average linear velocity in the column is 25 cm/s. Injector and flame-ionization detector temperatures are 280 degrees C, oven temperature 35 degrees C. Chromatography time is less than 3 min.

Evaluation of Capillary Gas Chromatography for Multicomponent Drug Analysis

1986 ◽  
Vol 69 (5) ◽  
pp. 811-813
Author(s):  
Don W Thompson
Keyword(s):  
Gas Chromatography ◽  
Capillary Gas Chromatography ◽  
Drug Analysis ◽  
Fused Silica ◽  
Pharmacological Activities ◽  
Over The Counter ◽  
Silica Column ◽  
Drug Mixtures ◽  
Bonded Phase ◽  
Glass Column

Abstract Capillary gas chromatography is evaluated for multicomponent drug analysis. A 0.32 mm id × 30 m fused silica column and a 0.75 mm id × 30 m borosilicate glass column (both with OV-1 bonded phase) are investigated. Retention times (relative to caffeine) are presented for 39 drug components representing a variety of chemical classes and pharmacological activities. Reproducibility data are presented for both isothermal and programmed temperature runs on selected drug mixtures. Recovery data are provided for 2 multicomponent drug mixtures prepared to approximate over-the-counter antihistaminic and antitussive preparations.

Determination of Benzene in Polypropylene Food-Packaging Materials and Food-Contact Paraffin Waxes

1991 ◽  
Vol 74 (2) ◽  
pp. 367-374
Author(s):  
Sandra L Varner ◽  
Henry C Hollifield ◽  
Denis Andrzejewski
Keyword(s):  
Gas Chromatography ◽  
Food Packaging ◽  
Fused Silica ◽  
Paraffin Wax ◽  
Gas Chromatography Mass Spectrometry ◽  
Food Contact ◽  
Limit Of Quantitation ◽  
Headspace Gas ◽  
Paraffin Waxes

Abstract An analytical procedure was developed for determination of benzene in polypropylene food packaging and was adapted for determination of benzene in commercial paraffin waxes Intended for food-contact use. The polymer was dissolved in hexadecane at 150°C. The wax was melted in an 80°C oven. A simple helium-sparging apparatus was used to remove the volatile chemical from the polymer or wax. The contaminant was collected In methanol, distilled water was added, and the resulting solution was analyzed by headspace gas chromatography. The Instrument was equipped with a 30 m fused silica open tubular capillary column and a photoionization detector. Average recoveries of benzene from polymer and paraffin wax at low parts-per-billion concentrations were 63 and 70%, respectively. Limits of detection and quantitation for analysis of polypropylene were 8 and 17 ppb, respectively; the limit of quantitation for analysis of paraffin wax was 2 ppb. in several commercial polypropylene products examined, benzene levels ranged from none detected to 426 ppb. In 3 commercial waxes examined, concentrations of 16-73 ppb benzene were determined. The presence of benzene was confirmed by gas chromatography/mass spectrometry

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