Preoperative adjuvant radiation with chemotherapy for rectal cancer: Its impact on stage of disease and the role of endorectal ultrasound

1996 ◽  
Vol 3 (2) ◽  
pp. 131-135 ◽  
Author(s):  
Andrea Bernini ◽  
Kemal I. Deen ◽  
Robert D. Madoff ◽  
W. Douglas Wong
Keyword(s):  
Rectal Cancer ◽  
Endorectal Ultrasound ◽  
Adjuvant Radiation ◽  
Stage Of Disease

scholarly journals Fifty shades of grey: The role of endorectal ultrasound in rectal cancer staging

2013 ◽  
Vol 11 (8) ◽  
pp. 629-630
Author(s):  
Adam Smith ◽  
David Griffith ◽  
Jeremy Williamson ◽  
Rami Radwan ◽  
Mark Davies ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Cancer Staging ◽  
Endorectal Ultrasound ◽  
Rectal Cancer Staging ◽  
Fifty Shades Of Grey

scholarly journals The Role of 3-D Endorectal Ultrasound in Rectal Cancer: Our Experience

2014 ◽  
Vol 99 (2) ◽  
pp. 106-111 ◽  
Author(s):  
Nikola Y. Kolev ◽  
Anton Y. Tonev ◽  
Valentin L. Ignatov ◽  
Aleksander K. Zlatarov ◽  
Vasil M. Bojkov ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Rectal Wall ◽  
Preoperative Staging ◽  
Three Dimensional ◽  
Cancer Staging ◽  
Endorectal Ultrasound ◽  
Diagnostic Methods ◽  
Diagnostic Modality ◽  
Locoregional Staging

Abstract In the last 20 years, endorectal ultrasound (ERUS) has been one of the main diagnostic methods for locoregional staging of rectal cancer. ERUS is accurate modality for evaluating local invasion of rectal carcinoma into the rectal wall layers (T category). Adding the three-dimensional modality (3-D) increases the capabilities of this diagnostic tool in rectal cancer patients. We review the literature and report our experience in preoperative 3-D ERUS in rectal cancer staging. In the group of 71 patients, the staging of preoperative 3-D endorectal ultrasonography was compared with the postoperative morphologic examination. Three-dimensional ERUS preoperative staging was confirmed with morphologic evaluation in 66 out of 71 cases (92.9%). The detection sensitivities of rectal cancer with 3-D ERUS were as follows: T1, 92.8%; T2, 93.1%; T3, 91.6%; and T4, 100.0%; with specificity values of T1, 98.2%; T2, 95.4%; T3, 97.8%; and T4, 98.5%. Three-dimensional ERUS correctly categorized patients with T1, 97.1%; T2, 94.3%; T3, 95.7%; and T4, 98.5%. The percentage of total overstaged cases was 2.75% and that of understaged cases was 6.87%. The metastatic status of the lymph nodes was determined with a sensitivity of 79.1% (19 of 24), specificity of 91.4% (43 of 47), and diagnostic accuracy of 87.3% (62 of 71). In our experience, 3-D ERUS has the potential to become the diagnostic modality of choice for the preoperative staging of rectal cancer.

The Role of MRI in Treatment Planning for Rectal Cancer - A Review

2013 ◽  
Vol 9 (2) ◽  
pp. 111-116
Author(s):  
R.K. Bott ◽  
M. Chand ◽  
G.F. Nash ◽  
R.I. Swift ◽  
G. Brown
Keyword(s):  
Rectal Cancer ◽  
Treatment Planning

scholarly journals Can Pre-Treatment Inflammatory Parameters Predict the Probability of Sphincter-Preserving Surgery in Patients with Locally Advanced Low-Lying Rectal Cancer?

Diagnostics ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 946
Author(s):  
Richard Partl ◽  
Katarzyna Lukasiak ◽  
Bettina Stranz ◽  
Eva Hassler ◽  
Marton Magyar ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Anal Verge ◽  
Locally Advanced ◽  
Multivariable Analysis ◽  
Sphincter Preservation ◽  
Independent Predictive Factor ◽  
Lymphocyte Ratio ◽  
Inflammatory Parameters ◽  
Pre Treatment

There is evidence suggesting that pre-treatment clinical parameters can predict the probability of sphincter-preserving surgery in rectal cancer; however, to date, data on the predictive role of inflammatory parameters on the sphincter-preservation rate are not available. The aim of the present cohort study was to investigate the association between inflammation-based parameters and the sphincter-preserving surgery rate in patients with low-lying locally advanced rectal cancer (LARC). A total of 848 patients with LARC undergoing radiotherapy from 2004 to 2019 were retrospectively reviewed in order to identify patients with rectal cancer localized ≤ 6 cm from the anal verge, treated with neo-adjuvant radiochemotherapy (nRCT) and subsequent surgery. Univariable and multivariable analyses were used to investigate the role of pre-treatment inflammatory parameters, including the C-reactive protein (CRP), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) for the prediction of sphincter preservation. A total of 363 patients met the inclusion criteria; among them, 210 patients (57.9%) underwent sphincter-preserving surgery, and in 153 patients (42.1%), an abdominoperineal rectum resection was performed. Univariable analysis showed a significant association of the pre-treatment CRP value (OR = 2.548, 95% CI: 1.584–4.097, p < 0.001) with sphincter preservation, whereas the pre-treatment NLR (OR = 1.098, 95% CI: 0.976–1.235, p = 0.120) and PLR (OR = 1.002, 95% CI: 1.000–1.005, p = 0.062) were not significantly associated with the type of surgery. In multivariable analysis, the pre-treatment CRP value (OR = 2.544; 95% CI: 1.314–4.926; p = 0.006) was identified as an independent predictive factor for sphincter-preserving surgery. The findings of the present study suggest that the pre-treatment CRP value represents an independent parameter predicting the probability of sphincter-preserving surgery in patients with low-lying LARC.

scholarly journals Role of postoperative radiotherapy in pT3N0 rectal cancer: A risk‐stratification system based on population analyses

2019 ◽  
Vol 8 (3) ◽  
pp. 1024-1033 ◽  
Author(s):  
Yun‐xia Huang ◽  
Yan‐zong Lin ◽  
Jin‐luan Li ◽  
Xue‐qing Zhang ◽  
Li‐rui Tang ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Risk Stratification ◽  
Postoperative Radiotherapy ◽  
Population Analyses ◽  
Stratification System ◽  
Risk Stratification System
Sign in / Sign up

Export Citation Format

Share Document