Superficial extremity soft tissue sarcoma: An analysis of prognostic factors

1998 ◽  
Vol 5 (1) ◽  
pp. 41-47 ◽  
Author(s):  
Ari D. Brooks ◽  
Martin J. Heslin ◽  
Denis H. Y. Leung ◽  
Jonathan J. Lewis ◽  
Murray F. Brennan
Keyword(s):  
Prognostic Factors ◽  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Extremity Soft Tissue Sarcoma

scholarly journals Prognostic Factors Predictive of Survival and Local Recurrence for Extremity Soft Tissue Sarcoma

1994 ◽  
Vol 219 (2) ◽  
pp. 165-173 ◽  
Author(s):  
Samuel Singer ◽  
Joseph M. Corson ◽  
Rene Gonin ◽  
Brian Labow ◽  
Timothy J. Eberlein
Keyword(s):  
Prognostic Factors ◽  
Soft Tissue ◽  
Local Recurrence ◽  
Soft Tissue Sarcoma ◽  
Extremity Soft Tissue Sarcoma

scholarly journals Prognostic Factors in Extremity Soft Tissue Sarcoma Patients Treated with Preoperative Radiotherapy

2019 ◽  
Vol 4 (03) ◽  
Author(s):  
Berrin Inanc, MD ◽  
Kubilay Inanc, MD
Keyword(s):  
Prognostic Factors ◽  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Preoperative Radiotherapy ◽  
Soft Tissue Sarcomas ◽  
Tumor Grade ◽  
Metastatic Recurrence ◽  
Extremity Soft Tissue Sarcoma ◽  
Metastatic Relapse

Purpose: The purpose of the study was to investigate the prognostic factors and survival after preoperative radiotherapy in Extremity Soft Tissue Sarcomas (ESTS). Materials and Methods: In this retrospective study, all patients treated for an extremity sarcoma with pre-operative radiotherapy followed by surgery. Results: The mean follow-up for all 24 ESTS patients was 15.5 (range: 10-39 months). At last follow-up, 9 patients (37%) were alive, 15 patients (62%) had died of distant disease progression. Among the patients died, there were 15 with metastatic relapse (13 lung and 2 cranial metastasis), 5 with both local and metastatic recurrence. The median OS was 16 month. The 2-years actuarial OS rate and 3-years OS rate were 39% and 26%, respectively. The median RFS was 14(12.5-15.4) month. The 2-years and 3-years RFS rate was 71%.The median MFS was 12 months. The 2-years and 3-years MFS rate were 33%, 17%, respectively. The effects of age, sex, histopathologic type, tumor size, tumor localization, tumor grade, tumor depth, radiation doses and recestion margin on OS, RFS, MFS were not observed. In univariate and multivariate model, it was observed that recurrence decreased OS time significantly (p<0.05). Conclusion: Recurrens and metastasis are strong and negative prognostic factor for survival in extremity soft tissue sarcoma patients.

Prognostic factors of extremity soft tissue sarcoma in adults. A single institutional analysis

2012 ◽  
Vol 16 (8) ◽  
pp. 661-666 ◽  
Author(s):  
I. Atean ◽  
Y. Pointreau ◽  
P. Rosset ◽  
P. Garaud ◽  
G. De-Pinieux ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Institutional Analysis ◽  
Extremity Soft Tissue Sarcoma

Localized Extremity Soft Tissue Sarcoma: Improved Knowledge With Unchanged Survival Over Time

2003 ◽  
Vol 21 (14) ◽  
pp. 2719-2725 ◽  
Author(s):  
Jürgen Weitz ◽  
Christina R. Antonescu ◽  
Murray F. Brennan
Keyword(s):  
Risk Factors ◽  
Prognostic Factors ◽  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Current Therapy ◽  
Disease Specific Survival ◽  
Actuarial Survival ◽  
Extremity Soft Tissue Sarcoma ◽  
Risk Patients ◽  
Disease Specific

Purpose: The objective of this study was to define whether survival of patients with extremity soft tissue sarcoma (STS), stratified for known risk factors, has improved over the last 20 years. Patients and Methods: From January 1982 to December 2001, 1,706 patients with primary and recurrent STS of the extremities were treated at our institution and were prospectively followed. From this cohort, we selected 1,261 patients who underwent complete macroscopic resection and had one of the following histopathologies: fibrosarcoma, liposarcoma, leiomyosarcoma, malignant fibrous histiocytoma, or synovial sarcoma. Median follow-up was 55 months. Patient, tumor, and treatment factors were analyzed as prognostic factors. Results: The 5-year disease-specific actuarial survival was 79% (78% for patients treated from 1982 to 1986, 79% for patients treated from 1986 to 1991, 79% for patients treated from 1992 to 1996, and 85% for patients treated from 1997 to 2001; P = not significant). For high-risk patients (high-grade, > 10 cm, deep tumors; n = 247), 5-year disease-specific survival was 51% (50% for patients treated from 1982 to 1986, 45% for patients treated from 1986 to 1991, 52% for patients treated from 1992 to 1996, and 61% for patients treated from 1997 to 2001; P = not significant). Tumor depth, size, grade, microscopic margin status, patient age, presentation status (primary tumor versus local recurrence), location (proximal versus distal), and certain histopathologic subtypes were significant prognostic factors for disease-specific survival on multivariate analysis; however, time period of treatment was not. Conclusion: Prognosis of patients with extremity STS, stratified for known risk factors, has not improved over the last 20 years, indicating that current therapy has reached the limits of efficacy.

Prognostic factors for local recurrence and survival in patients with localized extremity soft-tissue sarcoma

1988 ◽  
Vol 4 (1) ◽  
pp. 30-37 ◽  
Author(s):  
Charles F. Collin ◽  
Claudia Friedrich ◽  
James Godbold ◽  
Steven Hajdu ◽  
Murray F. Brennan
Keyword(s):  
Prognostic Factors ◽  
Soft Tissue ◽  
Local Recurrence ◽  
Soft Tissue Sarcoma ◽  
Extremity Soft Tissue Sarcoma

EP-1274 PROGNOSTIC FACTORS OF EXTREMITY SOFT TISSUE SARCOMA IN ADULTS. A SINGLE INSTITUTIONAL ANALYSIS

2012 ◽  
Vol 103 ◽  
pp. S486
Author(s):  
Y. Pointreau ◽  
I. Atean ◽  
P. Rosset ◽  
P. Garaud ◽  
G. De Pinieux ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Institutional Analysis ◽  
Extremity Soft Tissue Sarcoma
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