Dynamics of production oftrans-zeatin andtrans-zeatin riboside by immobilized cytokinin-autonomous and cytokinin-dependent tobacco cells

1987 ◽  
Vol 6 (3) ◽  
pp. 147-157 ◽  
Author(s):  
Radomíra Vaňková ◽  
Miroslav Kamínek ◽  
Josef Eder ◽  
Tomáš Vaněk
Planta ◽  
1987 ◽  
Vol 172 (4) ◽  
pp. 520-525 ◽  
Author(s):  
C. E. Hansen ◽  
Frederick Meins ◽  
Roland Aebi

1995 ◽  
Vol 95 (1) ◽  
pp. 120-126 ◽  
Author(s):  
Kent D. Chapman ◽  
Allison Conyers-Jackson ◽  
Robert A. Moreau ◽  
Swati Tripathy
Keyword(s):  

Biomics ◽  
2018 ◽  
Vol 10 (1) ◽  
pp. 62-68
Author(s):  
A.V. Korobova ◽  
G.R. Akhiyarova ◽  
S.S. Medvedev ◽  
S.Yu. Veselov ◽  
G.R. Kudoyarova
Keyword(s):  

Molecules ◽  
2021 ◽  
Vol 26 (2) ◽  
pp. 361
Author(s):  
Gabriel Gonzalez ◽  
Jiří Grúz ◽  
Cosimo Walter D’Acunto ◽  
Petr Kaňovský ◽  
Miroslav Strnad

Cytokinins are adenine-based phytohormones that regulate key processes in plants, such as cell division and differentiation, root and shoot growth, apical dominance, branching, and seed germination. In preliminary studies, they have also shown protective activities against human neurodegenerative diseases. To extend knowledge of the protection (protective activity) they offer, we investigated activities of natural cytokinins against salsolinol (SAL)-induced toxicity (a Parkinson’s disease model) and glutamate (Glu)-induced death of neuron-like dopaminergic SH-SY5Y cells. We found that kinetin-3-glucoside, cis-zeatin riboside, and N6-isopentenyladenosine were active in the SAL-induced PD model. In addition, trans-, cis-zeatin, and kinetin along with the iron chelator deferoxamine (DFO) and the necroptosis inhibitor necrostatin 1 (NEC-1) significantly reduced cell death rates in the Glu-induced model. Lactate dehydrogenase assays revealed that the cytokinins provided lower neuroprotective activity than DFO and NEC-1. Moreover, they reduced apoptotic caspase-3/7 activities less strongly than DFO. However, the cytokinins had very similar effects to DFO and NEC-1 on superoxide radical production. Overall, they showed protective activity in the SAL-induced model of parkinsonian neuronal cell death and Glu-induced model of oxidative damage mainly by reduction of oxidative stress.


1981 ◽  
Vol 68 (4) ◽  
pp. 937-940 ◽  
Author(s):  
Ivan K. Smith
Keyword(s):  

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