Optimisation of post-column reaction detector for HPLC of explosives

1993 ◽  
Vol 35 (1-2) ◽  
pp. 5-12 ◽  
Author(s):  
H. Engelhardt ◽  
J. Meister ◽  
P. Kolla
Keyword(s):  
Reaction Detector

Reaction detector with three dimensional coiled open tubes in HPLC

1982 ◽  
Vol 15 (7) ◽  
pp. 403-408 ◽  
Author(s):  
H. Engelhardt ◽  
U. D. Neue
Keyword(s):  
Three Dimensional ◽  
Reaction Detector

Analysis of aldehydes in cloud- and fogwater samples by HPLC with a postcolumn reaction detector

1989 ◽  
Vol 23 (5) ◽  
pp. 556-561 ◽  
Author(s):  
Manabu Igawa ◽  
J. William Munger ◽  
Michael R. Hoffmann
Keyword(s):  
Reaction Detector

scholarly journals Reactomics: using mass spectrometry as a reaction detector

2019 ◽  
Author(s):  
Miao Yu ◽  
Lauren Petrick
Keyword(s):  
Mass Spectrometry ◽  
High Resolution ◽  
Small Molecules ◽  
High Resolution Mass Spectrometry ◽  
A Priori ◽  
Mass Spectrometry Data ◽  
Biological Impact ◽  
Reaction Discovery ◽  
Reaction Detector ◽  
Biological Fate

AbstractUntargeted metabolomics analysis captures chemical reactions among small molecules. Common mass spectrometry-based metabolomics workflows first identify the small molecules significantly associated with the outcome of interest, then begin exploring their biochemical relationships to understand biological fate (environmental studies) or biological impact (physiological response). We suggest an alternative by which biochemical relationships can be directly retrieved through untargeted high-resolution paired mass distance (PMD) analysis without a priori knowledge of the identities of participating compounds. Retrieval is done using high resolution mass spectrometry as a chemical reaction detector, where PMDs calculated from the mass spectrometry data are linked to biochemical reactions obtained via data mining of small molecule and reaction databases, i.e. ‘Reactomics’. We demonstrate applications of reactomics including PMD network analysis, source appointment of unknown compounds, and biomarker reaction discovery as a complement to compound discovery analyses used in traditional untargeted workflows. An R implementation of reactomics analysis and the reaction/PMD databases is available as the pmd package (https://yufree.github.io/pmd/).

scholarly journals ANALYSIS OF ALDEHYDES IN FOGWATER BY HPLC WITH POSTCOLUMN REACTION DETECTOR

1991 ◽  
Vol 7 (Supple) ◽  
pp. 133-134
Author(s):  
Hiroshi Suzaki ◽  
Manabu Igawa
Keyword(s):  
Reaction Detector
Sign in / Sign up

Export Citation Format

Share Document