Physico-chemical modelling of solute retention in reversed-phase HPLC with temary mobile phases

1989 ◽  
Vol 28 (7-8) ◽  
pp. 354-358 ◽  
Author(s):  
Teresa Kowalska
Keyword(s):  
Reversed Phase ◽  
Reversed Phase Hplc ◽  
Solute Retention ◽  
Mobile Phases ◽  
Physico Chemical ◽  
Chemical Modelling

Acetonitrile as tops solvent for liquid chromatography and extraction

2018 ◽  
Vol 1 (2) ◽  
Author(s):  
Oleg Borisovich Rudakov ◽  
Liudmila V. Rudakova ◽  
Vladimir F. Selemenev
Keyword(s):  
Mobile Phase ◽  
Chemical Properties ◽  
Refraction Index ◽  
Extraction Methods ◽  
Reversed Phase ◽  
Liquid Extraction ◽  
Liquid Liquid Extraction ◽  
Optic Density ◽  
Mobile Phases ◽  
Physico Chemical

This article deals with acetonitrile physico-chemical properties and its mixtures with water. It covers the information about isotherms of such parameters of the acetonitrile-water binary system as density, viscosity, permeation coefficient, refraction index, optic density, a boiling point isobar. Authors suggest a generalized criterion of acetonitrile polarity. The article also discusses means of polarity assessment and eluotropic strength of mobile phases on the basis of acetonitrile mixtures with water with application of generalized criteria. Special attention is paid to the options of acetonitrile application in various extraction methods of chromatographic sample preparation. The article also reveals advantages and problems of acetonitrile application as a mobile phase modifying agent in the HPLC reversed-phase and as a hydrophilic extra-agent in liquid-liquid extraction.

scholarly journals Separation and lipophilicity of some new steroid derivatives in normal- and reversed-phase high performance liquid chromatography

2011 ◽  
Vol 17 (4) ◽  
pp. 535-542 ◽  
Author(s):  
Marijana Acanski ◽  
Djura Vujuc ◽  
Suzana Jovanovic-Santa
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Stationary Phase ◽  
High Performance ◽  
Reversed Phase ◽  
Log P ◽  
Reversed Phase Hplc ◽  
Mobile Phases

The separation ability and retention of normal and reversed phase HPLC with, respectively, three non-polar and two polar mobile phases, have been studied by measuring the retention constants of a series of newly synthesized estrone derivatives. The separation ability and retention are discussed in terms of the nature of the solute, eluent and stationary phase. Good correlation was found between the retention constants log k0 of newly synthesized estrone derivatives obtained on C-18 column and log P calculated by different methods.

scholarly journals Normal and reversed phase high performance liquid chromatography of some new 1, 2, 4-triazole derivatives

2003 ◽  
pp. 83-92 ◽  
Author(s):  
Marijana Acanski ◽  
Nada Perisic-Janjic ◽  
Vesna Dimova
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Stationary Phase ◽  
High Performance ◽  
Reversed Phase ◽  
Reversed Phase Hplc ◽  
Triazole Derivatives ◽  
Retention Behaviour ◽  
Mobile Phases

The retention behaviour and separation ability of normal and reversed phase HPLC with one non-polar and two polar mobile phases, have been studied by measuring the retention constants of a series of newly synthesized 1,2,4-triazole derivatives. The results are discussed in terms of the nature of the solute, eluent and stationary phase.

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