Evidence for the involvement of dopamine D1 and D2 receptors in mediating the decrease of food intake during repeated treatment with amphetamine

2001 ◽  
Vol 8 (6) ◽  
pp. 462-466 ◽  
Author(s):  
Tzy-Yen Chen ◽  
Sheau-Ling Duh ◽  
Chiun-Chien Huang ◽  
Tzer-Bin Lin ◽  
Dong-Yih Kuo
1990 ◽  
Vol 186 (2-3) ◽  
pp. 223-230 ◽  
Author(s):  
Sanders A. McDougall ◽  
Timothy F. Arnold ◽  
Arthur J. Nonneman

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Qing Ye ◽  
Xiao-Lei Yuan ◽  
Jie Zhou ◽  
Can-xing Yuan ◽  
Xu-ming Yang

This study was performed to observe the effects of Zishenpingchan granule on neurobehavioral manifestations and the activity and gene expression of striatal dopamine D1 and D2 receptors of rats with levodopa-induced dyskinesias (LID). We established normal control group, LID model group, and TCM intervention group. Each group received treatment for 4 weeks. Artificial neural network (ANN) was applied to excavate the main factor influencing variation in neurobehavioral manifestations of rats with LID. The results showed that overactivation in direct pathway mediated by dopamine D1 receptor and overinhibition in indirect pathway mediated by dopamine D2 receptor may be the main mechanism of LID. TCM increased the efficacy time of LD to ameliorate LID symptoms effectively mainly by upregulating dopamine D2 receptor gene expression.


2001 ◽  
Vol 69 (3-4) ◽  
pp. 409-418 ◽  
Author(s):  
Keith M Erikson ◽  
Byron C Jones ◽  
Ellen J Hess ◽  
Qian Zhang ◽  
John L Beard

1995 ◽  
Vol 269 (4) ◽  
pp. R896-R903 ◽  
Author(s):  
I. Bednar ◽  
H. Carrer ◽  
G. A. Qureshi ◽  
P. Sodersten

A dopamine D1 (SKF-38393, 1 mg)- or D2 (LY-171555, 0.1 mg)-receptor agonist inhibited intake of an intraorally infused solution of sucrose by male rats, a test of consummatory ingestive behavior. Treatment with a D1 (SCH-39166, 0.1 mg) or D2 (raclopride, 0.6 mg) antagonist reversed inhibition by the respective agonist but enhanced the inhibitory effect of cholecystokinin octapeptide (CCK-8; 1.8 micrograms). It was not possible to demonstrate specific effects of D1 and D2 agonists on intake of pellets, a test that does not discriminate consummatory ingestive behavior from appetitive ingestive behavior, i.e., behavior used to obtain food. The results demonstrate specific involvement of dopamine D1 and D2 receptors in inhibition of consummatory ingestive behavior.


1993 ◽  
Vol 32 (6) ◽  
pp. 515-517 ◽  
Author(s):  
P NEEDHAM ◽  
M SKILL ◽  
A COWAN ◽  
R REDFERN ◽  
D HEAL

1994 ◽  
Vol 14 (10) ◽  
pp. 6144-6152 ◽  
Author(s):  
MS Hooks ◽  
JL Juncos ◽  
JB Justice ◽  
SM Meiergerd ◽  
SL Povlock ◽  
...  

2017 ◽  
Vol 234 (16) ◽  
pp. 2475-2487 ◽  
Author(s):  
Haiyang Xu ◽  
Sasmita Das ◽  
Marc Sturgill ◽  
Colin Hodgkinson ◽  
Qiaoping Yuan ◽  
...  

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