P300 event-related potential amplitude as an endophenotype of alcoholism — Evidence from the collaborative study on the genetics of alcoholism

2001 ◽  
Vol 8 (1) ◽  
pp. 77-82 ◽  
Author(s):  
Victor Hesselbrock ◽  
Henri Begleiter ◽  
Bernice Porjesz ◽  
Sean O'Connor ◽  
Lance Bauer
Keyword(s):  
Collaborative Study ◽  
Event Related Potential ◽  
Potential Amplitude ◽  
P300 Event Related Potential

P300 Event-Related Potential Amplitude as an Endophenotype of Alcoholism – Evidence from the Collaborative Study on the Genetics of Alcoholism

2001 ◽  
Vol 8 (1) ◽  
pp. 77-82 ◽  
Author(s):  
Victor Hesselbrock ◽  
Henri Begleiter ◽  
Bernice Porjesz ◽  
Sean O’Connor ◽  
Lance Bauer
Keyword(s):  
Collaborative Study ◽  
Event Related Potential ◽  
Potential Amplitude

P300 Event-Related Potential Amplitude and Impulsivity in Cocaine-Dependent Subjects

2004 ◽  
Vol 50 (2) ◽  
pp. 167-173 ◽  
Author(s):  
F. Gerard Moeller ◽  
Ernest S. Barratt ◽  
Christian J. Fischer ◽  
Donald M. Dougherty ◽  
Edward L. Reilly ◽  
...  
Keyword(s):  
Event Related Potential ◽  
Potential Amplitude ◽  
P300 Event Related Potential

Tai Chi and meditation-plus-exercise benefit neural substrates of executive function: a cross-sectional, controlled study

2014 ◽  
Vol 11 (4) ◽  
Author(s):  
Teresa D. Hawkes ◽  
Wayne Manselle ◽  
Marjorie H. Woollacott
Keyword(s):  
Executive Function ◽  
Aerobic Exercise ◽  
Tai Chi ◽  
Neural Substrates ◽  
Event Related Potential ◽  
Controlled Study ◽  
Neural Function ◽  
Cross Sectional ◽  
P300 Event Related Potential

Abstract: We report the first controlled study of Tai Chi effects on the P300 event-related potential, a neuroelectric index of human executive function. Tai Chi is a form of exercise and moving meditation. Exercise and meditation have been associated with enhanced executive function. This cross-sectional, controlled study utilized the P300 event-related potential (ERP) to compare executive network neural function between self-selected long-term Tai Chi, meditation, aerobic fitness, and sedentary groups. We hypothesized that because Tai Chi requires moderate aerobic and mental exertion, this group would show similar or better executive neural function compared to meditation and aerobic exercise groups. We predicted all health training groups would outperform sedentary controls.: Fifty-four volunteers (Tai Chi, n=10; meditation, n=16; aerobic exercise, n=16; sedentary, n=12) were tested with the Rockport 1-mile walk (estimated VO: Only Tai Chi and meditation plus exercise groups demonstrated larger P3b ERP switch trial amplitudes compared to sedentary controls.: Our results suggest long-term Tai Chi practice, and meditation plus exercise may benefit the neural substrates of executive function.

Changes in prefrontal cortex near infrared spectroscopy activity as a function of difficulty in a visual P300 paradigm

2018 ◽  
Vol 26 (4) ◽  
pp. 222-228 ◽  
Author(s):  
Will Rizer ◽  
Jacob S Aday ◽  
Joshua M Carlson
Keyword(s):  
Prefrontal Cortex ◽  
Task Difficulty ◽  
Near Infrared ◽  
Nir Spectroscopy ◽  
Event Related Potential ◽  
Attentional Resources ◽  
Oddball Task ◽  
The Right ◽  
Visual P300 ◽  
P300 Event Related Potential

The P300 event-related potential is an index of attentional resources related to target detection. Source localization and functional magnetic resonance imaging (fMRI) research has indicated that, among other regions, the prefrontal cortex contributes to the generation of the P300. Similar to fMRI, near infrared (NIR) spectroscopy measures change in blood oxygen levels, but offers several advantages including portability, low expense, and superior temporal resolution. No studies to date have examined the extent to which prefrontal cortex NIR spectroscopy measures are active during the P300 paradigm. To address this knowledge gap, participants completed a two-difficulty visual oddball task in which NIR spectroscopy and P300 data were collected in a counterbalanced order. Confirmatory results indicate that the P300 event-related potential is attenuated as a function of task difficulty. Similarly, NIR spectroscopy measures of oxygenated hemoglobin in the right medial prefrontal cortex are attenuated as a function of task difficulty. The results suggest that prefrontal cortex NIR spectroscopy measures are sensitive to task difficulty in a visual P300 oddball task.

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