Incidence of fast bone losers and factors affecting changes in bone mineral density: A cohort study in a rural Japanese community

1996 ◽  
Vol 14 (3) ◽  
pp. 171-177 ◽  
Author(s):  
Noriko Yoshimura
2013 ◽  
Vol 8 (1-2) ◽  
Author(s):  
E. M. Dennison ◽  
D. K. Dhanwal ◽  
S. O. Shaheen ◽  
R. Azagra ◽  
I. Reading ◽  
...  

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Serap Zengin Karahan ◽  
Cavit Boz ◽  
Sevgi Kilic ◽  
Nuray Can Usta ◽  
Mehmet Ozmenoglu ◽  
...  

Multiple sclerosis (MS) has been associated with reduced bone mineral density (BMD). The purpose of this study was to determine the possible factors affecting BMD in patients with MS. We included consecutive 155 patients with MS and 90 age- and sex-matched control subjects. Patients with MS exhibited significantly lowerT-scores andZ-scores in the femoral neck and trochanter compared to the controls. Ninety-four (61%) patients had reduced bone mass in either the lumbar spine or the femoral neck; of these, 64 (41.3%) had osteopenia and 30 (19.4%) had osteoporosis. The main factors affecting BMD were disability, duration of MS, and smoking. There was a negative relationship between femoral BMD and EDSS and disease duration. No association with lumbar BMD was determined. There were no correlations between BMD at any anatomic region and cumulative corticosteroid dose. BMD is significantly lower in patients with MS than in healthy controls. Reduced BMD in MS is mainly associated with disability and duration of the disease. Short courses of high dose steroid therapy did not result in an obvious negative impact on BMD in the lumbar spine and femoral neck in patients with MS.


2012 ◽  
Vol 45 (5) ◽  
pp. 470 ◽  
Author(s):  
Jeong Sook Choe ◽  
Eun Mi Ahn ◽  
Sung Ok Kwon ◽  
Young Hee Park ◽  
Jinyoung Lee

2020 ◽  
Author(s):  
Kazumi Taguchi ◽  
Shuzo Hamamoto ◽  
Atsushi Okada ◽  
Yutaro Tanaka ◽  
Teruaki Sugino ◽  
...  

Abstract Background: Patients with urolithiasis have a lower bone mineral density (BMD) than those without stones, suggesting a potential correlation between calcium stone formation and bone resorption disorders, including osteopenia and osteoporosis. Methods: To investigate the influence of BMD on clinical outcomes in urolithiasis, we performed a single-center retrospective cohort study to analyze patients with urolithiasis who underwent both BMD examination and 24-hour urine collection between 2006 and 2015. Data from the national cross-sectional surveillance of the Japanese Society on Urolithiasis Research in 2015 were utilized, and additional data related to urinary tract stones were obtained from medical records. The primary outcome was the development of stone-related symptoms and recurrences during follow-up. A total of 370 patients were included in this 10-year study period. Results: Half of the patients had recurrent stones, and the two-thirds were symptomatic stone formers. While only 9% of patients had hypercalciuria, 27% and 55% had hyperoxaluria and hypocitraturia, respectively. There was a positive correlation between T-scores and urinary citrate excretion. Both univariate and multivariate analyses demonstrated that female sex was associated with recurrences (odds ratio=0.44, p=0.007), whereas a T-score <−2.5 and hyperoxaluria were associated with symptoms (odds ratio=2.59, p=0.037; odds ratio=0.45, p=0.01; respectively). Conclusion: These results revealed that low T-scores might cause symptoms in patients with urolithiasis, suggesting the importance of BMD examination for high-risk Japanese patients with urolithiasis having hypocitraturia.


Bone Reports ◽  
2020 ◽  
Vol 13 ◽  
pp. 100571
Author(s):  
Thomas Emmanuel ◽  
Julius Simoni Leere ◽  
Christian Kruse ◽  
Trine Holmgaard Poulsen ◽  
Peter Vestergaard

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