Experimental infection of the African buffalo with the virus of Rift Valley fever

1981 ◽  
Vol 13 (1) ◽  
pp. 185-188 ◽  
Author(s):  
F. G. Davies ◽  
L. Karstad
Keyword(s):  
Experimental Infection ◽  
Rift Valley ◽  
Rift Valley Fever ◽  
African Buffalo ◽  
Valley Fever

scholarly journals Seroprevalence of Rift Valley fever and lumpy skin disease in African buffalo (Syncerus caffer) in the Kruger National Park and Hluhluwe-iMfolozi Park, South Africa

2014 ◽  
Vol 85 (1) ◽  
Author(s):  
Shamsudeen Fagbo ◽  
Jacobus A.W. Coetzer ◽  
Estelle H. Venter
Keyword(s):  
Skin Disease ◽  
Rift Valley ◽  
National Park ◽  
Rift Valley Fever ◽  
Kruger National Park ◽  
African Buffalo ◽  
Neutralising Antibodies ◽  
Valley Fever ◽  
Lumpy Skin Disease ◽  
Antibody Titres

Rift Valley fever and lumpy skin disease are transboundary viral diseases endemic in Africa and some parts of the Middle East, but with increasing potential for global emergence. Wild ruminants, such as the African buffalo (Syncerus caffer), are thought to play a role in the epidemiology of these diseases. This study sought to expand the understanding of the role of buffalo in the maintenance of Rift Valley fever virus (RVFV) and lumpy skin disease virus (LSDV) by determining seroprevalence to these viruses during an inter-epidemic period. Buffaloes from the Kruger National Park (n = 138) and Hluhluwe-iMfolozi Park (n = 110) in South Africa were sampled and tested for immunoglobulin G (IgG) and neutralising antibodies against LSDV and RVFV using an indirect enzyme-linked immunosorbent assay (I-ELISA) and the serum neutralisation test (SNT). The I-ELISA for LSDV and RVFV detected IgG antibodies in 70 of 248 (28.2%) and 15 of 248 (6.1%) buffaloes, respectively. Using the SNT, LSDV and RVFV neutralising antibodies were found in 5 of 66 (7.6%) and 12 of 57 (21.1%), respectively, of samples tested. The RVFV I-ELISA and SNT results correlated well with previously reported results. Of the 12 SNT RVFV-positive sera, three (25.0%) had very high SNT titres of 1:640. Neutralising antibody titres of more than 1:80 were found in 80.0% of the positive sera tested. The LSDV SNT results did not correlate with results obtained by the I-ELISA and neutralising antibody titres detected were low, with the highest (1:20) recorded in only two buffaloes, whilst 11 buffaloes (4.4%) had evidence of co-infection with both viruses. Results obtained in this study complement other reports suggesting a role for buffaloes in the epidemiology of these diseases during inter-epidemic periods.

scholarly journals Enemies and turncoats: bovine tuberculosis exposes pathogenic potential of Rift Valley fever virus in a common host, African buffalo ( Syncerus caffer )

2015 ◽  
Vol 282 (1805) ◽  
pp. 20142942 ◽  
Author(s):  
B. R. Beechler ◽  
C. A. Manore ◽  
B. Reininghaus ◽  
D. O'Neal ◽  
E. E. Gorsich ◽  
...  
Keyword(s):  
Bovine Tuberculosis ◽  
Rift Valley ◽  
Rift Valley Fever ◽  
Bacterial Disease ◽  
African Buffalo ◽  
Free Living ◽  
Pathogenic Potential ◽  
Valley Fever ◽  
Fitness Effects ◽  
Combining Data

The ubiquity and importance of parasite co-infections in populations of free-living animals is beginning to be recognized, but few studies have demonstrated differential fitness effects of single infection versus co-infection in free-living populations. We investigated interactions between the emerging bacterial disease bovine tuberculosis (BTB) and the previously existing viral disease Rift Valley fever (RVF) in a competent reservoir host, African buffalo, combining data from a natural outbreak of RVF in captive buffalo at a buffalo breeding facility in 2008 with data collected from a neighbouring free-living herd of African buffalo in Kruger National Park. RVF infection was twice as likely in individual BTB+ buffalo as in BTB− buffalo, which, according to a mathematical model, may increase RVF outbreak size at the population level. In addition, co-infection was associated with a far higher rate of fetal abortion than other infection states. Immune interactions between BTB and RVF may underlie both of these interactions, since animals with BTB had decreased innate immunity and increased pro-inflammatory immune responses. This study is one of the first to demonstrate how the consequences of emerging infections extend beyond direct effects on host health, potentially altering the dynamics and fitness effects of infectious diseases that had previously existed in the ecosystem on free-ranging wildlife populations.

scholarly journals Experimental Infection of Calves by Two Genetically-Distinct Strains of Rift Valley Fever Virus

Viruses ◽  
2016 ◽  
Vol 8 (5) ◽  
pp. 145 ◽  
Author(s):  
William Wilson ◽  
A. Davis ◽  
Natasha Gaudreault ◽  
Bonto Faburay ◽  
Jessie Trujillo ◽  
...  
Keyword(s):  
Experimental Infection ◽  
Rift Valley ◽  
Rift Valley Fever ◽  
Rift Valley Fever Virus ◽  
Fever Virus ◽  
Valley Fever

scholarly journals Serological Evidence of Rift Valley Fever Virus Circulation in Domestic Cattle and African Buffalo in Northern Botswana (2010–2011)

2015 ◽  
Vol 2 ◽  
Author(s):  
Ferran Jori ◽  
Kathleen A. Alexander ◽  
Mokganedi Mokopasetso ◽  
Suzanne Munstermann ◽  
Keabetswe Moagabo ◽  
...  
Keyword(s):  
Rift Valley ◽  
Rift Valley Fever ◽  
Rift Valley Fever Virus ◽  
Fever Virus ◽  
African Buffalo ◽  
Serological Evidence ◽  
Valley Fever

Experimental Infection of Young Adult European Breed Sheep with Rift Valley Fever Virus Field Isolates

2010 ◽  
Vol 10 (7) ◽  
pp. 689-696 ◽  
Author(s):  
Nuria Busquets ◽  
F. Xavier ◽  
Raquel Martín-Folgar ◽  
Gema Lorenzo ◽  
Iván Galindo-Cardiel ◽  
...  
Keyword(s):  
Young Adult ◽  
Experimental Infection ◽  
Rift Valley ◽  
Rift Valley Fever ◽  
Rift Valley Fever Virus ◽  
Fever Virus ◽  
European Breed ◽  
Valley Fever ◽  
Field Isolates ◽  
Breed Sheep

Recombinant nucleocapsid-based ELISA for detection of IgG antibody to Rift Valley fever virus in African buffalo

2008 ◽  
Vol 127 (1-2) ◽  
pp. 21-28 ◽  
Author(s):  
Janusz T. Paweska ◽  
Petrus Jansen van Vuren ◽  
Alan Kemp ◽  
Peter Buss ◽  
Roy G. Bengis ◽  
...  
Keyword(s):  
Rift Valley ◽  
Rift Valley Fever ◽  
Rift Valley Fever Virus ◽  
Fever Virus ◽  
African Buffalo ◽  
Igg Antibody ◽  
Valley Fever
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