Natural killer (NK) cells at inflammatory sites of patients with rheumatoid arthritis and IgM rheumatoid factor positive polyarticular juvenile rheumatoid arthritis

1987 ◽  
Vol 6 (2) ◽  
pp. 215-225 ◽  
Author(s):  
J. Thoen ◽  
K. Waalen ◽  
Ø. Førre
Keyword(s):  
Rheumatoid Arthritis ◽  
Nk Cells ◽  
Rheumatoid Factor ◽  
Natural Killer ◽  
Juvenile Rheumatoid Arthritis ◽  
Igm Rheumatoid Factor

scholarly journals Hidden 19S IgM Rheumatoid Factor in Juvenile Rheumatoid Arthritis

1980 ◽  
Vol 14 (10) ◽  
pp. 1135-1138 ◽  
Author(s):  
Terry L Moore ◽  
Robert W Dorner ◽  
Terry D Weiss ◽  
Andrew R Baldassare ◽  
Jack Zuckner
Keyword(s):  
Rheumatoid Arthritis ◽  
Rheumatoid Factor ◽  
Juvenile Rheumatoid Arthritis ◽  
Igm Rheumatoid Factor

scholarly journals Hidden 19S IgM rheumatoid factor in adults with juvenile rheumatoid arthritis onset.

1985 ◽  
Vol 44 (5) ◽  
pp. 294-298 ◽  
Author(s):  
J C Speiser ◽  
T L Moore ◽  
T D Weiss ◽  
A R Baldassare ◽  
S C Ross ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Rheumatoid Factor ◽  
Juvenile Rheumatoid Arthritis ◽  
Igm Rheumatoid Factor

Specificity of hidden 19s igm rheumatoid factor in patients with juvenile rheumatoid arthritis

1981 ◽  
Vol 24 (10) ◽  
pp. 1283-1290 ◽  
Author(s):  
Terry L. Moore ◽  
Robert W. Dorner ◽  
Terry D. Weiss ◽  
Andrew R. Baldassare ◽  
Jack Zuckner
Keyword(s):  
Rheumatoid Arthritis ◽  
Rheumatoid Factor ◽  
Juvenile Rheumatoid Arthritis ◽  
Igm Rheumatoid Factor

scholarly journals IgM rheumatoid factor plaque-forming cells in juvenile rheumatoid arthritis

1987 ◽  
Vol 30 (3) ◽  
pp. 335-338 ◽  
Author(s):  
Terry L. Moore ◽  
Eva El-Najdawi ◽  
Robert W. Dorner
Keyword(s):  
Rheumatoid Arthritis ◽  
Rheumatoid Factor ◽  
Juvenile Rheumatoid Arthritis ◽  
Igm Rheumatoid Factor

scholarly journals High prevalence of iga rheumatoid factor in severe polyarticular-onset juvenile rheumatoid arthritis, but not in systemic-onset or pauciarticular-onset disease

1990 ◽  
Vol 33 (2) ◽  
pp. 199-204 ◽  
Author(s):  
Sharyn M. Walker ◽  
Deborah K. Mccurdy ◽  
Bracha Shaham ◽  
Riva Brik ◽  
Heidi Wietting ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Rheumatoid Factor ◽  
Juvenile Rheumatoid Arthritis ◽  
High Prevalence ◽  
Systemic Onset

Utility of Rheumatoid Factor in the Diagnosis of Juvenile Rheumatoid Arthritis

PEDIATRICS ◽  
1986 ◽  
Vol 78 (3) ◽  
pp. 480-484 ◽  
Author(s):  
Andrew H. Eichenfield ◽  
Balu H. Athreya ◽  
Robert A. Doughty ◽  
Randall D. Cebul
Keyword(s):  
Rheumatoid Arthritis ◽  
Rheumatoid Factor ◽  
Juvenile Rheumatoid Arthritis ◽  
Pediatric Rheumatology ◽  
Diagnostic Value ◽  
Clinical Settings ◽  
Older Children ◽  
Predictive Values ◽  
Negative Results ◽  
Outpatient Settings

Rheumatoid factor is commonly used by clinicians to assess children with possible juvenile rheumatoid arthritis. To assess its usefulness, we reviewed the case histories of patients in whom latex agglutinating rheumatoid factor was determined during 1981 to 1982 at our institution. A total of 437 charts were available for review. There were 11 patients with positive tests for rheumatoid factor, of whom five had juvenile rheumatoid arthritis, all polyarticular. A total of 426 children had negative results, of whom 100 had juvenile rheumatoid arthritis. This yields a sensitivity of 4.8% and a specificity of 98%. We then estimated the prevalence of juvenile rheumatoid arthritis in three clinical settings: a primary practitioner's office, a tertiary children's hospital walk-in clinic, and a pediatric rheumatology center. The predictive values and marginal benefits for rheumatoid factor were then calculated in those settings using Bayes' theorem. In the two general outpatient settings, the primary practitioner's office and tertiary walk-in clinic, the positive predictive values were 0.7% and 0.5%, respectively; marginal benefits were 0.4% and 0.3%, respectively. Rheumatoid factor testing appeared to be of some benefit in the pediatric rheumatology center with a positive predictive value of 72.5% and marginal benefit of 22.5%. In no case was rheumatoid factor testing helpful in establishing a diagnosis of juvenile rheumatoid arthritis or in ruling it out. Testing for rheumatoid factor is a poor screening procedure for juvenile rheumatoid arthritis in the general situations in which it is more likely to be requested and of supportive diagnostic value only in the highly restricted population of older children with polyarticular arthritis.

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