Haversian bone formation rates determined by a new method in a mastodon, and in human diabetes mellitus and osteoporosis

1970 ◽  
Vol 6 (1) ◽  
pp. 204-219 ◽  
Author(s):  
K. Wu ◽  
K. E. Schubeck ◽  
H. M. Frost ◽  
A. Villanueva
Keyword(s):  
Diabetes Mellitus ◽  
Bone Formation ◽  
New Method ◽  
Human Diabetes

scholarly journals Mechanisms of Increased Vascular Superoxide Production in Human Diabetes Mellitus

Circulation ◽  
2002 ◽  
Vol 105 (14) ◽  
pp. 1656-1662 ◽  
Author(s):  
Tomasz J. Guzik ◽  
Shafi Mussa ◽  
Daniela Gastaldi ◽  
Jerzy Sadowski ◽  
Chandi Ratnatunga ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Superoxide Production ◽  
Human Diabetes

Epidemiology of Urolithiasis and Calcium Metabolism in Human Diabetes Mellitus

1985 ◽  
pp. 47-50 ◽  
Author(s):  
W. Tschöpe ◽  
E. Ritz ◽  
M. Haslbeck ◽  
H. Mehnert ◽  
D. Deppermann
Keyword(s):  
Diabetes Mellitus ◽  
Calcium Metabolism ◽  
Human Diabetes

scholarly journals Diabetes Mellitus—With a New Method of Prognosis.

JAMA ◽  
1904 ◽  
Vol XLIII (6) ◽  
pp. 412
Author(s):  
Heinrich Stern
Keyword(s):  
Diabetes Mellitus ◽  
New Method

scholarly journals Effect of Cholecalciferol Supplementation on Bone Turnover Markers in Children and Adolescents With Type 1 Diabetes Mellitus

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A274-A274
Author(s):  
Volodymyr I Pankiv ◽  
Ivan V Pankiv
Keyword(s):  
Diabetes Mellitus ◽  
Vitamin D ◽  
Bone Formation ◽  
Children And Adolescents ◽  
Bone Markers ◽  
Vitamin D Supplementation ◽  
Procollagen Type ◽  
Amino Terminal ◽  
Cholecalciferol Supplementation

Abstract Background: Cholecalciferol is known to play an important role in bone mineral metabolism. Its deficiency may affect growth and status of bone markers in children. Aim of the study: to evaluate the correlation between serum 25(OH)D and bone markers and impact of vitamin D supplementation on serum bone formation [procollagen type 1 amino-terminal propeptide (P1NP)] and bone resorption [β-cross laps (CTx)] markers among children and adolescents with type 1 diabetes mellitus (DM). Materials and Methods: Total 58 children and adolescents with type 1 DM, who were given 2000 UI of cholecalciferol supplementation, were included in the study. These 58 children with available anthropometry, serum biochemistry, 25-hydroxyvitamin D ([25(OH)D]), and parathormone (PTH) were evaluated for bone formation (procollagen type 1 amino-terminal propeptide [P1NP]) and resorption (β-cross laps [CTx]) markers. Results: The mean age and body mass index of these children were 11.6 ± 2.3 years (boys: 11.7 ± 2.4; girls: 12.2 ± 1.4 years; p = 0.04) and 18.2 ± 3.9 kg/m2 (boys: 18.1 ± 3.8; girls: 17.8 ± 3.4 kg/m2; p = 0.206), respectively. Baseline serum P1NP levels were positively correlated with serum phosphates (r = 0.281, p < 0.001), PTH (r = 0.291, p < 0.001), and CTx (r = 0.425, p < 0.001) but not with age (r = -0.016, p = 0.404), BMI (r = -0.080, p = 0.032), serum calcium (r = -0.038, p = 0.107), and baseline 25(OH)D (r = -0.069, p = 0.035). Postsupplementation serum P1NP and CTx levels maintained similar correlations. There was a significant decline in serum P1NP (from 681 ± 223 ng/ml to 630 ± 279 ng/ml, p < 0.01) and CTx (from 1.63 ± 0.51 ng/ml to 1.37 ± 0.53 ng/ml, p < 0.01) following supplementation. Though decline in serum P1NP and CTx levels was observed in both boys and girls, among all supplementation patients, the effect was more marked in serum CTx than P1NP levels. Conclusions: Vitamin D supplementation in children resulted in decrease in both bone formation (P1NP) and resorption (CTx). The impact, however, was more marked on bone resorption than bone formation.

Hyperglycemia and Obesity as Determinants of Glucose, Insulin, and Glucagon Responses toβ-Endorphin in Human Diabetes Mellitus

1987 ◽  
Vol 64 (6) ◽  
pp. 1122-1128 ◽  
Author(s):  
DARIO GIUGLIANO ◽  
TERESA SALVATORE ◽  
DOMENICO COZZOLINO ◽  
ANTONIO CERIELLO ◽  
ROBERTO TORELLA ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Human Diabetes

Yucatan Miniature Swine as a Model for the Study of Human Diabetes Mellitus

Diabetes ◽  
1982 ◽  
Vol 31 (Supplement_1) ◽  
pp. 30-36 ◽  
Author(s):  
R. W. Phillips ◽  
L. M. Panepinto ◽  
R. Spangler ◽  
N. Westmoreland
Keyword(s):  
Diabetes Mellitus ◽  
Miniature Swine ◽  
Human Diabetes

Dogs with Induced or Spontaneous Diabetes as Models for the Study of Human Diabetes Mellitus

Diabetes ◽  
1982 ◽  
Vol 31 (Supplement_1) ◽  
pp. 26-29 ◽  
Author(s):  
R. L. Engerman ◽  
J. W. Kramer
Keyword(s):  
Diabetes Mellitus ◽  
Spontaneous Diabetes ◽  
Human Diabetes
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