Improved 4D NMR experiments for the assignment of backbone nuclei in13C/15N labelled proteins

1992 ◽  
Vol 2 (6) ◽  
pp. 631-637 ◽  
Author(s):  
Wayne Boucher ◽  
Ernest D. Laue ◽  
Sharon L. Campbell-Burk ◽  
Peter J. Domaille
Keyword(s):  
4D Nmr

A set of 4D NMR experiments of enhanced resolution for easy resonance assignment in proteins

2010 ◽  
Vol 202 (1) ◽  
pp. 109-116 ◽  
Author(s):  
Anna Zawadzka-Kazimierczuk ◽  
Krzysztof Kazimierczuk ◽  
Wiktor Koźmiński
Keyword(s):  
Resonance Assignment ◽  
Enhanced Resolution ◽  
4D Nmr

Sequential assignment of the backbone nuclei (1H,15N and13C) of c-H-ras p21 (1–166).GDP using a novel 4D NMR strategy

1992 ◽  
Vol 2 (6) ◽  
pp. 639-646 ◽  
Author(s):  
Sharon L. Campbell-Burka ◽  
Peter J. Domaillea ◽  
Melissa A. Starovasnik ◽  
Wayne Boucher ◽  
Ernest D. Laue
Keyword(s):  
Sequential Assignment ◽  
Ras P21 ◽  
4D Nmr

scholarly journals Isotope-Filtered 4D NMR Spectroscopy for Structure Determination of Humic Substances

2015 ◽  
Vol 127 (29) ◽  
pp. 8502-8505
Author(s):  
Nicholle G. A. Bell ◽  
Adam A. L. Michalchuk ◽  
John W. T. Blackburn ◽  
Margaret C. Graham ◽  
Dušan Uhrín
Keyword(s):  
Nmr Spectroscopy ◽  
Humic Substances ◽  
Structure Determination ◽  
4D Nmr

scholarly journals Nuclear Magnetic Resonance Spectroscopyan Evolutionary Approach to Drug Design

2007 ◽  
Vol 4 (3) ◽  
pp. 294-301
Author(s):  
Neeraj Upmanyu ◽  
Gopal Garg ◽  
Archana Dolly ◽  
Pradeep Mishra
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Drug Discovery ◽  
Magnetic Resonance ◽  
Drug Design ◽  
Small Molecules ◽  
Pharmaceutical Research ◽  
Three Dimensional ◽  
Drug Discovery And Development ◽  
4D Nmr ◽  
Nuclear Magnetic

Ever since Nuclear Magnetic Resonance (NMR) spectroscopy hit the analytical scene; its capabilities and applications continue to evolve. Originally designed as a way to verify the structure of relatively small compounds, the technology of NMR has exploded and become a valuable means for studying protein structure. NMR has proved to be a valuable tool in pharmaceutical research, as it has entered new arena of drug discovery and structural genomics. NMR can provide information on the three-dimensional structures of small molecules in solution, high-molecular-weight complexes, and the details of enzyme mechanisms that can be used to aid in drug design. In the present scenario, the availability of high magnetic fields; improved software, high resolution probes, and electronics; more versatile pulse programmers; and most importantly the development of 2D, 3D and 4D NMR, have revolutionized the field of drug discovery and development.

4D NMR triple-resonance experiments for assignment of protein backbone nuclei using shared constant-time evolution periods

1992 ◽  
Vol 98 (2) ◽  
pp. 443-450 ◽  
Author(s):  
Lewis E Kay ◽  
Michael Wittekind ◽  
Mark A McCoy ◽  
Mark S Friedrichs ◽  
Luciano Mueller
Keyword(s):  
Time Evolution ◽  
Constant Time ◽  
Triple Resonance ◽  
Protein Backbone ◽  
Triple Resonance Experiments ◽  
4D Nmr

scholarly journals Isotope-Filtered 4D NMR Spectroscopy for Structure Determination of Humic Substances

2015 ◽  
Vol 54 (29) ◽  
pp. 8382-8385 ◽  
Author(s):  
Nicholle G. A. Bell ◽  
Adam A. L. Michalchuk ◽  
John W. T. Blackburn ◽  
Margaret C. Graham ◽  
Dušan Uhrín
Keyword(s):  
Nmr Spectroscopy ◽  
Humic Substances ◽  
Structure Determination ◽  
4D Nmr

Estimation of Variable Fluids Mixture Density With 4D NMR Logging

2007 ◽  
Author(s):  
Chanh Cao Minh ◽  
Emmanuel Caroli ◽  
Padmanabhan Sundararaman
Keyword(s):  
Nmr Logging ◽  
Mixture Density ◽  
4D Nmr

scholarly journals NMR methodology for complex mixture ‘separation’

2014 ◽  
Vol 50 (14) ◽  
pp. 1694-1697 ◽  
Author(s):  
Nicholle G. A. Bell ◽  
Lorna Murray ◽  
Margaret C. Graham ◽  
Dušan Uhrín
Keyword(s):  
Complex Mixture ◽  
Mixture Separation ◽  
4D Nmr

Mixture ‘separation’ by NMR is demonstrated through the development of a pseudo 4D NMR experiment, 3D IPAP INEPT-INADEQUATE-HSQC.

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