ATPase activity of guinea pig heart muscle

1956 ◽  
Vol 12 (6) ◽  
pp. 224-226
Author(s):  
Maria Assunta Mor
Keyword(s):  
Guinea Pig ◽  
Atpase Activity ◽  
Heart Muscle ◽  
Guinea Pig Heart

scholarly journals Effects of Novel Synthesized Pyridothiazines on Various Guinea Pig Heart Muscle Preparations

2004 ◽  
Vol 27 (9) ◽  
pp. 1364-1370 ◽  
Author(s):  
Bettina Schade ◽  
Thomas Erker ◽  
Manuela Weber ◽  
Christian Studenik
Keyword(s):  
Guinea Pig ◽  
Heart Muscle ◽  
Guinea Pig Heart

Ultrastructural and enzymatic development of fetal guinea pig heart

1982 ◽  
Vol 243 (1) ◽  
pp. H87-H93 ◽  
Author(s):  
T. P. Rolph ◽  
C. T. Jones ◽  
D. Parry
Keyword(s):  
Guinea Pig ◽  
Atpase Activity ◽  
Enzyme Activities ◽  
Citric Acid Cycle ◽  
Acid Metabolism ◽  
Fetal Heart ◽  
Glycolytic Enzyme ◽  
Guinea Pig Heart ◽  
Threefold Increase ◽  
Phosphofructokinase Activity

The activities of some enzymes of glycolysis, the citric acid cycle, and amino acid metabolism have been measured in the fetal guinea pig heart over the last third of gestation and correlated with heart ultrastructural development. There is little change in glycolytic enzyme activity except for a two- to threefold increase in phosphofructokinase activity. Mitochondrial content and enzyme activities are low in the early fetal heart, and, although content is similar in the late fetus and adult, enzyme activities increase twofold postnatally, indicating fetal heart mitochondria are incompletely developed. The activities of aspartate and particularly alanine aminotransferase are low in the fetal heart. Over the last third of gestation the myofibrillar content of the fetal myocyte increases twofold to the adult value by term. Associated with this is a fourfold rise in myofibrillar and sarcoplasmic reticulum Ca2+-ATPase activity. Na+-K+-ATPase activity is similar in the late fetal and adult heart but one-third lower in the early fetal heart.

A375 EFFECT OF ORDER OF ADMINISTRATION OF AMRINONE AND DOBUTAHINB ON GUINEA-PIG HEART MUSCLE

1990 ◽  
Vol 73 (3A) ◽  
pp. NA-NA
Author(s):  
R. C. Cork ◽  
S Behr ◽  
S Hackev ◽  
J DiNardo
Keyword(s):  
Guinea Pig ◽  
Heart Muscle ◽  
Guinea Pig Heart ◽  
Order Of Administration

Oxidation of citrate by mitochondria from guinea pig heart, liver and kidney

1961 ◽  
Vol 200 (2) ◽  
pp. 355-358 ◽  
Author(s):  
Menard M. Gertler ◽  
Dino Mancini
Keyword(s):  
Guinea Pig ◽  
Heart Muscle ◽  
Tissue Preparation ◽  
Guinea Pig Heart ◽  
Atp Level ◽  
Liver And Kidney ◽  
Choice Of Species

There is no unanimity concerning the ability of mitochondrial systems from heart, liver and kidney to oxidize citrate. This disparity stems partly from lack of uniformity in the choice of species and partly from the mode of tissue preparation. The present results have been obtained with mitochondria prepared from guinea pig heart, liver and kidney. The QNOO2 for citrate at 2 mm ATP level is highest in kidney, 590, followed by liver, 417 and heart, 255. Kidney and liver oxidations are accompanied by phosphorylations while oxidation of citrate in the cardiac preparations are unaccompanied by any phosphorylation. Further differences are manifested by lowering ATP level in the medium to 0.33 mm. There is a decrease in the QNOO2 in liver and kidney with no change in phosphorylation ability, while the QNOO2 in the heart is increased by 25%. Greatest changes are those observed by addition of DPN and TPN which inordinately increase QNOO2 in the heart muscle, particularly at lower levels of ATP. Addition of CoA has virtually no effect on the QNOO2 or P/O ratios in any of the tissue preparations.

Sign in / Sign up

Export Citation Format

Share Document