Effect of a protein deficient diet upon some enzymatic activities of the brain, lung, and kidney of rats

1952 ◽  
Vol 8 (8) ◽  
pp. 306-307 ◽  
Author(s):  
Nora Bargoni ◽  
M. Cafiero ◽  
S. di Bella ◽  
E. de Mori ◽  
M. A. Grillo
Keyword(s):  
Enzymatic Activities ◽  
Deficient Diet ◽  
Protein Deficient Diet ◽  
The Brain ◽  
Lung And Kidney

Oxidative stress induced by morphine in brain of rats fed with a protein deficient diet

2009 ◽  
Vol 28 (9) ◽  
pp. 577-582 ◽  
Author(s):  
David Calderón-Guzmán ◽  
Norma Osnaya-Brizuela ◽  
Raquel García-Alvarez ◽  
Ernestina Hernández-García ◽  
Hugo Juárez-Olguín
Keyword(s):  
Oxidative Stress ◽  
Atpase Activity ◽  
Morphine Sulphate ◽  
Cellular Regulation ◽  
Deficient Diet ◽  
Group I ◽  
Protein Deficient Diet ◽  
Male Wistar Rats ◽  
The Brain ◽  
Experimental Group

The objective of the study is to determine the damage by oxidative stress induced by morphine in brain of rats fed with a protein-deficient diet. Twenty-eight malnourished male Wistar rats, 30 days old, were used in the study. The animals were divided into four groups of 7 rats per group. Group I received NaCl and the groups II; III and IV intraperitoneally received 3, 6 and 12 mg/kg of morphine sulphate, respectively, in a single dose. Animals were sacrificed and the levels of glutathione (GSH), dopamine, tryptophan and 5-hydroxyindole-3-acetic acid (5-HIAA) as well as, Na+/K+ ATPase and total ATPase activity in the brain were measured. Tryptophan levels and Na+/K + ATPase activity showed non-significant changes in the experimental group. Levels of 5-HIAA decreased significantly (p = .03) in animals that received 12 mg/kg of morphine and in animals that received 3 mg/kg, levels of GSH and dopamine were found to have a significant decrease (p < .05), but a significant increase in the group that received 12 mg/kg of morphine (p < .05). Total ATPase activity increased significantly in the groups that received 3 mg/kg (p = .015) and 6 mg/kg (p = .0001) of morphine. The results show that malnutrition induces changes in cellular regulation and biochemical responses to oxidative stress caused by morphine sulphate.

scholarly journals Veterinary needs of dogs in two resource-limited communities in the Gauteng and North West provinces of South Africa

2001 ◽  
Vol 72 (4) ◽  
Author(s):  
W.N. Minnaar ◽  
R.C. Krecek
Keyword(s):  
South Africa ◽  
Health Status ◽  
Body Condition ◽  
Veterinary Services ◽  
Structured Interviews ◽  
Deficient Diet ◽  
North West ◽  
The North ◽  
Resource Limited ◽  
Protein Deficient Diet

Information on the socioeconomic aspects and the health status of dogs in 2 resource-limited communities in the North West and Gauteng provinces of South Africa was gathered using semi-structured interviews and a standardised questionnaire. The dogs were examined clinically to determine their health status, and their body condition and age were scored. Most of the dogs (93 % in Jericho and 90 % in Zuurbekom) were infected with hookworm, which poses a threat to animal and human health in the 2 study areas. Many dogs were also being given a protein-deficient diet, which together with hookworm parasites would impact considerably on the dog's health. Dogs were mainly kept for security reasons. The need indicated to be most important by the residents of the 2 commnities was a lack of available and affordable veterinary services.

scholarly journals Iberian pig adaptation to acorn consumption: I. Net portal appearance of metabolites

PeerJ ◽  
2018 ◽  
Vol 6 ◽  
pp. e5861 ◽  
Author(s):  
Ignacio Fernández-Fígares ◽  
Jose Miguel Rodríguez-López ◽  
Lucrecia González-Valero ◽  
Manuel Lachica
Keyword(s):  
Sampling Period ◽  
Metabolic Energy ◽  
Blood Collection ◽  
Standard Diet ◽  
Deficient Diet ◽  
Protein Energy ◽  
Sampling Session ◽  
Protein Deficient Diet ◽  
Portal Plasma ◽  
Set Up

Most valuable cured products from Iberian pigs come from pure bred animals raised for a final grazing-fattening period where pigs eat mainly acorns, a low protein energy rich fruit. This is a nutritional challenge for animals fed equilibrated diets from weaning. The aim of the study was to determine net portal appearance (NPA) of metabolites in gilts fed acorns and evaluate adaptational changes after one week of feeding. Two sampling periods were carried out (after one day and after one week of acorn feeding) with six gilts (34 kg average BW) set up with three catheters: in carotid artery and portal vein for blood sampling, and ileal vein for para-aminohippuric acid (PAH) infusion to measure portal plasma flow (PPF). Pigs were fed at 2.5 × ME for maintenance a standard diet in two portions, at 09:00 (0.25) and 15:00 h (the remaining 0.75). On the day prior to the first sampling period, pigs were fed 2.4 kg of oak acorns. After feeding 0.25 of ration a 6 h serial blood collection was initiated. Following an identical protocol, a second sampling session was performed 1 week later. Adaptation to acorn consumption decreased NPA of ammonia (47%,P < 0.001). Although there was a transfer of urea from the gastrointestinal tract to the circulation in both sampling periods, no differences in NPA of urea was found (P > 0.05). NPA of glucose was not influenced by sampling period (P > 0.05), but NPA of lactate was greatly increased (231%,P < 0.001). There was a negative NPA of albumin although adaptation to acorn feeding did not alter it. Although NPA of triglycerides and cholesterol were unchanged, a subtle increase in arterial and portal cholesterol was noticed (9.6%,P < 0.01). Pigs fed a protein deficient diet for one week adapted decreasing NPA of ammonia for saving metabolic energy as less ammonia would become available for conversion to urea.

scholarly journals The effects of a tryptophan- and protein-deficient diet upon growth in rats

1989 ◽  
Vol 27 (4) ◽  
pp. 345-347 ◽  
Author(s):  
Angela H. Becker ◽  
Stephen F. Davis ◽  
Cathy A. Grover ◽  
Cynthia A. Erickson
Keyword(s):  
Deficient Diet ◽  
Protein Deficient Diet

LIPID METABOLISM AND LIPOPROTEIN SUSCEPTIBILITY TO PEROXIDATION ARE AFFECTED BY A PROTEIN-DEFICIENT DIET IN THE RAT

1997 ◽  
Vol 17 (1) ◽  
pp. 125-135 ◽  
Author(s):  
Corinne Moundras ◽  
Christian Demigné ◽  
Christine Morand ◽  
Marie-Anne Levrat ◽  
Christian Rémésy
Keyword(s):  
Lipid Metabolism ◽  
Deficient Diet ◽  
Protein Deficient Diet

scholarly journals INFLUENCE OF DIETARY PROTEIN CONTENT ON Trypanosoma cruzi INFECTION IN GERMFREE AND CONVENTIONAL MICE

1998 ◽  
Vol 40 (6) ◽  
pp. 355-362 ◽  
Author(s):  
Isa P. CINTRA ◽  
Marcelo E. SILVA ◽  
Marcílio E.C. SILVA ◽  
Márcio E. SILVA ◽  
L.C. C. AFONSO ◽  
...  
Keyword(s):  
Weight Gain ◽  
Trypanosoma Cruzi ◽  
Dietary Protein ◽  
Blood Cell Count ◽  
Deficient Diet ◽  
Low Protein ◽  
Protein Deficient Diet ◽  
Red Blood Cell Count ◽  
Cruzi Infection ◽  
Microbiological Status

Germfree (GF) and conventional (CV) mice were fed on diets containing 4.4, 13.2 or 26.4% of protein (weight/weight). CV mice fed on low protein diet did not gain weight during four weeks, whereas the protein deficient diet did not affect the growth of GF mice. After four weeks on these diets, the mice were inoculated with 5x103 trypomastigotes of Trypanosoma cruzi. The protein deficiency affected less the GF than the CV mice, according to the following parameters: weight gain, hemoglobin, plasma protein and albumin levels and water and protein contents of the carcass. Infection with T. cruzi produced a significant decrease in hemoglobin levels, red blood cell count, and water and protein contents in the carcass. This decrease was more pronounced in the GF mice. Histopathologically, there was no difference between the treatments in animals with the same microbiological status (GF or CV). However, the disease was more severe in the GF than in the CV mice.

scholarly journals The effect of protein-deficient isoenergetic diets on the growth of rat jejunal mucosa

1982 ◽  
Vol 48 (1) ◽  
pp. 25-36 ◽  
Author(s):  
Gabrielle Syme
Keyword(s):  
Surface Area ◽  
G Protein ◽  
Protein Deficiency ◽  
Male Rats ◽  
Jejunal Mucosa ◽  
Metaphase Arrest ◽  
Villus Height ◽  
Deficient Diet ◽  
Protein Deficient Diet ◽  
Delayed Maturation

1. Newly weaned 21-d-old male rats were given isoenergetic diets containing 200, 100 and 50 g protein/kg for 7, 14, 28 or 70 d. The mid-jejunum was removed from the rats and a micrometric analysis of the mucosa was made. The following measurements were made: number of villi/mm2, vilius dimensions, villus surface area, crypt depth, crypt: villus, the number of cells/crypt in metaphase arrest per h.2. Comparisons were made between animals of the same age but on different diets, and animals on the same diet but of different ages. The latter comparison gave information on the effect of protein deficiency on the pattern of maturation of each feature of The villus or crypt studied.3. The effect of protein deficiency was not consistent at each stage of maturation. For instance villus height was decreased when compared with the controls following 28 d on a protein-deficient diet but not after 7 or 70 d.4. The only measurement to be unaffected by protein deficiency was the number of villi per unit area.5. In general the 50 g protein/kg diet had a more pronounced effect than the 100 g protein/kg diet. Protein deficiency delayed maturation by either slowing or inhibiting changes seen in normal maturation.6. In rats given 50 g protein/kg diet, although the villus surface area did not increase as the rats matured there were increases in epithelial cell production rate and number of crypts per villus.

Exploring the brain tissue proteome of TgCRND8 Alzheimer's Disease model mice under B vitamin deficient diet induced hyperhomocysteinemia by LC-MS top-down platform

2019 ◽  
Vol 1124 ◽  
pp. 165-172
Author(s):  
Daniela Delfino ◽  
Diana Valeria Rossetti ◽  
Claudia Martelli ◽  
Ilaria Inserra ◽  
Federica Vincenzoni ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Brain Tissue ◽  
Disease Model ◽  
Top Down ◽  
Deficient Diet ◽  
B Vitamin ◽  
The Brain ◽  
Tissue Proteome

Atrophy and neuron loss: Effects of a protein-deficient diet on sympathetic neurons

2009 ◽  
Vol 87 (16) ◽  
pp. 3568-3575 ◽  
Author(s):  
Silvio Pires Gomes ◽  
Jens Randel Nyengaard ◽  
Rúbia Misawa ◽  
Priscila Azevedo Girotti ◽  
Patrìcia Castelucci ◽  
...  
Keyword(s):  
Sympathetic Neurons ◽  
Deficient Diet ◽  
Neuron Loss ◽  
Protein Deficient Diet
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