Inulin clearance and renal lymph

1964 ◽  
Vol 20 (11) ◽  
pp. 633-634 ◽  
Author(s):  
M. Papp ◽  
Marian Kovács
Keyword(s):  
Inulin Clearance ◽  
Renal Lymph

Simultaneous studies of hilar and capsular renal lymph

Life Sciences ◽  
1972 ◽  
Vol 11 (21) ◽  
pp. 1007-1010 ◽  
Author(s):  
James L. Atkins ◽  
Charles C.C. O'Morchoe ◽  
Gabriel G. Pinter
Keyword(s):  
Renal Lymph

The Characteristics of Renal Lymph

1968 ◽  
Vol 46 (4) ◽  
pp. P-27-P-27
Author(s):  
GH McIntosh ◽  
Bede Morris
Keyword(s):  
Renal Lymph

Renal glomerular filtration rate and hepatic blood flow during voluntary diving in Weddell seals

1983 ◽  
Vol 245 (5) ◽  
pp. R743-R748 ◽  
Author(s):  
R. W. Davis ◽  
M. A. Castellini ◽  
G. L. Kooyman ◽  
R. Maue
Keyword(s):  
Blood Flow ◽  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Hepatic Blood Flow ◽  
Filtration Rate ◽  
Hepatic Function ◽  
Inulin Clearance ◽  
Weddell Seals ◽  
Icg Clearance ◽  
The Mean

Renal and hepatic function were studied during voluntary dives in Weddell seals by measuring the clearance rate of inulin and indocyanine green (ICG). Inulin is cleared exclusively by the kidneys and measures renal glomerular filtration rate (GFR). ICG is cleared by the liver and is blood flow dependent at concentrations used. Studies were conducted from a portable hut with a trapdoor placed over an isolated hole in the sea ice near McMurdo Station, Antarctica. An intravertebral extradural catheter was inserted percutaneously under light anesthesia in subadult seals weighing 130-200 kg. When released into the ice hole, the seals made voluntary dives, but always had to return to breathe. Serial blood samples were taken after single injections of inulin and ICG and analyzed within 24 h. The mean half time (t 1/2) for inulin clearance while resting at the surface was 27.3 +/- 13.0 min (n = 43) and the mean t 1/2 for ICG clearance was 18.3 +/- 7.3 min (n = 23). The mean resting GFR was 3.6 ml X min-1 X kg-1 (range 3.2-3.9, n = 3). Inulin and ICG clearance rates did not change from resting levels during dives shorter than the seal's aerobic dive limit (ADL). Inulin clearance decreased over 90% during dives longer than the ADL, but there was no significant reduction in ICG clearance during dives lasting up to 23 min. It appears that normal renal GFR and hepatic blood flow continue during natural aerobic dives. During dives that exceed the ADL, GFR is reduced but hepatic blood flow may be maintained.

scholarly journals Renal lymph: a window for renal pathophysiology?

2016 ◽  
Vol 594 (6) ◽  
pp. 1519-1519
Author(s):  
C. Charles Michel
Keyword(s):  
Renal Lymph

Effects of growth hormone and IGF-I on renal function in rats with normal and reduced renal mass

1990 ◽  
Vol 259 (5) ◽  
pp. F747-F751 ◽  
Author(s):  
S. B. Miller ◽  
V. A. Hansen ◽  
M. R. Hammerman
Keyword(s):  
Growth Hormone ◽  
Renal Function ◽  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Renal Mass ◽  
Filtration Rate ◽  
Inulin Clearance ◽  
Mass Reduction ◽  
Contralateral Kidney ◽  
Igf I

To characterize actions of growth hormone (GH) and insulin-like growth factor ( (IGF-I) on renal function in rats with normal and reduced renal mass, we administered recombinant bovine growth hormone (bGH) or human IGF-I (hIGF-I) to normal rats or to rats that had undergone unilateral nephrectomy and two-thirds infarction of the contralateral kidney, and measured inulin and p-aminohippurate clearances over 10-17 days. Administration of either bGH (100-200 micrograms/day) or hIGF-I (200 micrograms/day) to rats with normal renal mass increased inulin and p-aminohippurate clearances compared with those measured in animals that received vehicle. Filtration fractions were not affected by either bGH or hIGF-I. Inulin clearance was decreased to approximately 17% of normal 1 day after reduction of renal mass in rats. Over the next 3 days insulin clearance increased significantly in rats with reduced renal mass that were administered vehicle. No further enhancement occurred during the next 7 days. Neither bGH nor hIGF-I affected inulin clearance in rats with reduced renal mass. We conclude that both GH and IGF-I enhance glomerular filtration rate when administered to rats with normal renal mass, but not when administered in the same quantities to rats in which renal functional mass is reduced. Glomerular filtration rate increases within 4 days of renal mass reduction independent of exogenous GH or IGF-I.

scholarly journals An easy to calculate equation to estimate GFR based on inulin clearance

2009 ◽  
Vol 24 (10) ◽  
pp. 3055-3061 ◽  
Author(s):  
D. Tsinalis ◽  
G. T. Thiel
Keyword(s):  
Inulin Clearance

Electrolyte excretion and free-water production during onset of acute diuresis

1975 ◽  
Vol 228 (5) ◽  
pp. 1304-1312 ◽  
Author(s):  
GH Mudge ◽  
WJ Cooke ◽  
WO Berndt
Keyword(s):  
Ethacrynic Acid ◽  
Collecting Duct ◽  
Chloride Concentration ◽  
Free Water ◽  
Inulin Clearance ◽  
Water Production ◽  
Electrolyte Excretion ◽  
Urinary Chloride ◽  
Transient Rise ◽  
Anesthetized Dogs

The concentration of major urinary solutes was studied in ureteral urine collected at 15- to 30-s intervals at the onset of acute diuresis induced in anesthetized dogs either by high-ceiling diuretics (mainly ethacrynic acid) or by osmotic diuretics. Phosphate/inulin clearance ratios remained unchanged; potassium/inulin clearance ratios rose rapidly. Principal attention is given to the mechanisms underlying a transient rise in urinary sodium and chloride concentrations during the onset of diuresis. When the data are corrected for washout artifacts from the pelvis and ureter, it can be shown that the initial collection periods are associated with a transient increase in free-water production and by the simultaneous secretion of urea from the interstitium into the tubular fluid. The former coincides in time with the rise in urinary chloride concentration and represents an augmentation of water reabsorbed in the collecting duct, which is relatively impermeable to chloride. Both responses are quantitatively consistent with the transition from a hyperosmotic to isosmotic medullary interstitium.

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