Quantitative properties of Müller cells in rabbit retina as revealed by histochemical demonstration of NADH-diaphorase activity

1983 ◽  
Vol 220 (2) ◽  
pp. 81-83 ◽  
Author(s):  
A. Reichenbach ◽  
F. Wohlrab
Keyword(s):  
Müller Cells ◽  
Histochemical Demonstration ◽  
Rabbit Retina ◽  
Muller Cells ◽  
Diaphorase Activity ◽  
Nadh Diaphorase ◽  
Quantitative Properties

ATP-evoked calcium responses of radial glial (Müller) cells in the postnatal rabbit retina

2002 ◽  
Vol 70 (2) ◽  
pp. 209-218 ◽  
Author(s):  
Ortrud Uckermann ◽  
Jens Grosche ◽  
Andreas Reichenbach ◽  
Andreas Bringmann
Keyword(s):  
Müller Cells ◽  
Rabbit Retina ◽  
Muller Cells ◽  
Radial Glial

Na+,K+-activated adenosine triphosphatase of isolated Müller cells from the rabbit retina shows a K+ dependence similar to that of brain astrocytes

1985 ◽  
Vol 59 (3) ◽  
pp. 281-284 ◽  
Author(s):  
Andreas Reichenbach ◽  
Dietrich Dettmer ◽  
Winfried Reichelt ◽  
Wolfgang Eberhardt
Keyword(s):  
Adenosine Triphosphatase ◽  
Müller Cells ◽  
Rabbit Retina ◽  
Muller Cells

Rabbit retinal neurons and glia express a variety of ENaC/DEG subunits

2002 ◽  
Vol 283 (1) ◽  
pp. C126-C134 ◽  
Author(s):  
L. M. Brockway ◽  
Z.-H. Zhou ◽  
J. K. Bubien ◽  
B. Jovov ◽  
D. J. Benos ◽  
...  
Keyword(s):  
Expression Patterns ◽  
Müller Cells ◽  
Immunohistochemical Localization ◽  
Mammalian Brain ◽  
Rabbit Retina ◽  
Muller Cells ◽  
Retinal Neurons ◽  
Cellular Expression ◽  
The Central Nervous System ◽  
First Time

Some members of the epithelial Na+ channel/degenerin (ENaC/DEG) family of ion channels have been detected in mammalian brain. Therefore, we examined the RNA and protein expression of these channels in another part of the central nervous system, the rabbit retina. We next sought to demonstrate physiological evidence for an amiloride-sensitive current in Müller glia, which, on the basis of a previous study, are thought to express α-ENaC (Golestaneh N, de Kozak Y, Klein C, and Mirshahi M. Glia 33: 160–168, 2001). RT-PCR of retinal RNA revealed the presence of α-, β-, γ-, and δ-ENaC as well as acid-sensing ion channel (ASIC)1, ASIC2, ASIC3, and ASIC4. Immunohistochemical localization with antibodies against α-ENaC and β-ENaC showed labeling in Müller cells and neurons, respectively. The presence of α-ENaC, β-ENaC, and ASIC1 was detected by Western blotting. Cultured Müller cells were whole cell patch clamped. These cells exhibited an inward Na+ current that was blocked by amiloride. These data demonstrate for the first time both the expression of a variety of ENaC and ASIC subunits in the rabbit retina as well as distinct cellular expression patterns of specific subunits in neurons and glia.

Development of the rabbit retina: II. Müller cells

1991 ◽  
Vol 311 (1) ◽  
pp. 33-44 ◽  
Author(s):  
A. Reichenbach ◽  
J. Schnitzer ◽  
A. Friedrich ◽  
A.-K. Knothe ◽  
A. Henke
Keyword(s):  
Müller Cells ◽  
Rabbit Retina ◽  
Muller Cells

K+ Channels of Müller Glial Cells in Retinal Disorders

2018 ◽  
Vol 17 (4) ◽  
pp. 255-260 ◽  
Author(s):  
Feng Gao ◽  
Lin-Jie Xu ◽  
Yuan Zhao ◽  
Xing-Huai Sun ◽  
Zhongfeng Wang
Keyword(s):  
Müller Cells ◽  
Major Type ◽  
Delayed Rectifier ◽  
Muller Cells ◽  
Bkca Channels ◽  
K Channels ◽  
Functional Changes ◽  
Physiological Properties ◽  
Retinal Disorders ◽  
Inwardly Rectifying

Background & Objective: Müller cell is the major type of glial cell in the vertebrate retina. Müller cells express various types of K+ channels, such as inwardly rectifying K+ (Kir) channels, big conductance Ca2+-activated K+ (BKCa) channels, delayed rectifier K+ channels (KDR), and transient A-type K+ channels. These K+ channels play important roles in maintaining physiological functions of Müller cells. Under some retinal pathological conditions, the changed expression and functions of K+ channels may contribute to retinal pathogenesis. Conclusion: In this article, we reviewed the physiological properties of K+ channels in retinal Müller cells and the functional changes of these channels in retinal disorders.

scholarly journals Melatonin attenuates oxidative stress and inflammation of Müller cells in diabetic retinopathy via activating the Sirt1 pathway

2021 ◽  
Vol 137 ◽  
pp. 111274
Author(s):  
Yuanyuan Tu ◽  
E Song ◽  
Zhenzhen Wang ◽  
Na Ji ◽  
Linling Zhu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Diabetic Retinopathy ◽  
Müller Cells ◽  
Muller Cells

Vitreous from idiopathic epiretinal membrane patients induces glial-to-mesenchymal transition in Müller cells

2021 ◽  
pp. 166181
Author(s):  
Adwaid Manu Krishna Chandran ◽  
Daniela Coltrini ◽  
Mirella Belleri ◽  
Sara Rezzola ◽  
Elena Gambicorti ◽  
...  
Keyword(s):  
Epiretinal Membrane ◽  
Müller Cells ◽  
Muller Cells ◽  
Mesenchymal Transition ◽  
Idiopathic Epiretinal Membrane
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