2. Principle and characteristics of the ROCHE tissue pH electrode

1978 ◽  
Vol 226 (1-2) ◽  
pp. 9-16 ◽  
Author(s):  
W. Mindt ◽  
H. Maurer ◽  
W. Möller
Keyword(s):  
Tissue Ph ◽  
Ph Electrode

10. Clinical experience in the application of the tissue pH electrode

1978 ◽  
Vol 226 (1-2) ◽  
pp. 69-73 ◽  
Author(s):  
W. Lichtenegger ◽  
E. Burghardt
Keyword(s):  
Clinical Experience ◽  
Tissue Ph ◽  
Ph Electrode

26. Experience with continuous tissue pH electrode in the human fetus during labor

1978 ◽  
Vol 226 (1-2) ◽  
pp. 175-180
Author(s):  
A. Zacutti ◽  
F. G. Ciuffi
Keyword(s):  
Human Fetus ◽  
Tissue Ph ◽  
Ph Electrode

An evaluation of the tissue pH electrode for fetal monitoring using the fetal sheep as an experimental model

1981 ◽  
Vol 140 (8) ◽  
pp. 953-960 ◽  
Author(s):  
Luca Fusi ◽  
Margaret Walmsley ◽  
Hubert G. Britton ◽  
David Redstone ◽  
Pauline D. Alexander ◽  
...  
Keyword(s):  
Experimental Model ◽  
Fetal Monitoring ◽  
Fetal Sheep ◽  
Tissue Ph ◽  
Ph Electrode

9. Application technique of tissue pH electrode on human fetuses

1978 ◽  
Vol 226 (1-2) ◽  
pp. 61-67
Author(s):  
S. Uzan ◽  
G. Sturbois ◽  
J. Salat-Baroux ◽  
C. Sureau
Keyword(s):  
Human Fetuses ◽  
Tissue Ph ◽  
Application Technique ◽  
Ph Electrode

Electrode and cuvette for rapid continuous CO2 tension and pH measurement in blood

1985 ◽  
Vol 59 (5) ◽  
pp. 1660-1664
Author(s):  
S. A. Katz ◽  
A. C. Roth ◽  
E. O. Feigl
Keyword(s):  
Carbonic Anhydrase ◽  
Response Time ◽  
Electrode Surface ◽  
Porous Ceramic ◽  
Reference Electrode ◽  
Silicone Membrane ◽  
Dimethyl Silicone ◽  
Glass Ph Electrode ◽  
Co2 Electrode ◽  
Ph Electrode

An electrode and cuvette system has been developed for the continuous and rapid measurement of either blood CO2 tension or pH. The CO2 electrode consists of a 1.5-mm-diameter flat-tip glass pH electrode covered by a film of carbonic anhydrase solution, over which a 25-micron-thick dimethyl silicone membrane is attached. Porous ceramic filled with 20% polyacrylamide, equilibrated with a salt solution, serves as a salt bridge between a Ag-AgCl reference electrode and the pH electrode surface. The electrode is housed in a four-port cuvette assembly. Blood from a vessel of interest is delivered to the cuvette by means of an occlusive roller pump. The cuvette maintains the electrode and blood at a constant temperature and directs a continuous jet of blood against the electrode surface. The cuvette also allows for easy and frequent calibration of the electrode with either gas or liquid standards. The 90% response time of the CO2 electrode is 3.0 s for liquids and 1.3 s for gases. Removal of the dimethyl silicone membrane and carbonic anhydrase film yields a pH electrode that can continuously measure blood pH with a 90% response time of 1.6 s.

Separation of carotid body chemoreceptor responses to O2 and CO2 by oligomycin and by antimycin A

1982 ◽  
Vol 242 (3) ◽  
pp. C200-C206 ◽  
Author(s):  
E. Mulligan ◽  
S. Lahiri
Keyword(s):  
Steady State ◽  
Carbonic Anhydrase ◽  
Partial Pressure ◽  
Carotid Body ◽  
Body Tissue ◽  
Antimycin A ◽  
Tissue Ph ◽  
Co2 Partial Pressure ◽  
O2 Partial Pressure ◽  
Metabolic Hypothesis

The cat carotid chemoreceptor O2 and CO2 responses can be separated by oligomycin and by antimycin A. Both of these agents greatly diminish or abolish the chemoreceptor O2 response but not the nicotine or CO2 responses. After either oligomycin or antimycin, the responses to increases and decreases in arterial CO2 partial pressure (PaCO2) consisted of increases and decreases in activity characterized respectively by exaggerated overshoots and undershoots. These were eliminated by the carbonic anhydrase inhibitor, acetazolamide, suggesting that they resulted from changes in carotid body tissue pH. The steady-state PaCO2 response remaining after oligomycin was no longer dependent on arterial O2 partial pressure (PaO2). All effects of antimycin were readily reversible in about 20 min. The separation of the responses to O2 and CO2 indicates that there may be at least partially separate pathways of chemoreception for these two stimuli. The similarity of the oligomycin and antimycin results supports the metabolic hypothesis of chemoreception.

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