Phosphatidic acid metabolism, calcium ions and transmitter release from electrically stimulated synaptosomes

1975 ◽  
Vol 8 (2) ◽  
pp. 83-87 ◽  
Author(s):  
J. N. Hawthorne ◽  
J. E. Bleasdale
Keyword(s):  
Phosphatidic Acid ◽  
Calcium Ions ◽  
Transmitter Release ◽  
Acid Metabolism

Differential phosphatidic acid metabolism in barley leaves and roots induced by chilling temperature

2018 ◽  
Vol 132 ◽  
pp. 174-182 ◽  
Author(s):  
Micaela Peppino Margutti ◽  
Virginia L. Gaveglio ◽  
Matias Reyna ◽  
Susana J. Pasquaré ◽  
Graciela E. Racagni ◽  
...  
Keyword(s):  
Phosphatidic Acid ◽  
Acid Metabolism ◽  
Chilling Temperature ◽  
Barley Leaves ◽  
Leaves And Roots

INTRACELLULAR AND EXTRACELLULAR CALCIUM IONS IN TRANSMITTER RELEASE AT THE NEUROMUSCULAR SYNAPSE

1978 ◽  
Vol 307 (1 Calcium Trans) ◽  
pp. 583-598 ◽  
Author(s):  
R. Rahamimoff ◽  
S.D. Erulkar ◽  
A. Lev-Tov ◽  
Halina Meiri
Keyword(s):  
Calcium Ions ◽  
Transmitter Release ◽  
Neuromuscular Synapse ◽  
Extracellular Calcium

ARACHIDGIIC ACID METABOLISM II PLATELETS STORED FOR FIVE DAYS

1987 ◽  
Author(s):  
J M Cascar ◽  
J L Kavarro
Keyword(s):  
Phosphatidic Acid ◽  
Acid Metabolism ◽  
Phosphatidyl Inositol ◽  
Platelet Concentrate ◽  
Phospholipases A

Arachidonlc acid (AA) netabolisn has been extensively studied in fresh platelets, but there Is little infomation available for stored platelets . we stored platelets in CLI bags far five days at 22+/-2°C and, on days 0, 3 and 5, six si of platelet concentrate were revved from the container and platelets were labeled with (C-14J-AA. Both incorporation and distribution of radiotracer sere studied in rest and thrcnfcln stivlated platelets.Total uptake of, (C-14)-AA dropped fron day 0 to 5 (p 0.01). Distribution oh day 0 was sinilar to fresh platelets. Incorporation of (C-14)-AA on phosphatidyl inositol (FI) decayed fron 12.4+/-1.5 on day 0, to 7.9+/-0.9 on day 3 (p 0.001), While the percentage attached on phosphatidylserine (PS),increased fron 5.3+/-0.9 to 8.8+/-1.5 (p 0.001). There were not any changes fron day 3 to 5.On day 0,17.7+/-5.2X of radiactlvity was released fron phospholipids by thronbin. This anount decreased to 7.3+/-2.5X (p 0.01) on day 5. I^xaiment in breakdown of both PI and phosphatidylcholine (PC) was detected. Generation of phosphatidic acid (PA) by thronbin, decreased fron 2.6+/-0.4X of total radiactlvity on day 0 to 1.4+/-0.3X on day 3 (p 0.001) and 0.9+/-0.2X on day 5 (p 0.01). Ve did not find changes in TxB2 and HHT, but HETE decayed fron 7.2+/-2.9X on day 0, to 2.3t/-0.9% on day 5 (p 0.01).We concluded that both activities of phospholipases A-2 and C are affected by storage.

Modulation of Transmitter Release by Calcium Ions and Nerve Impulses

1976 ◽  
Vol 40 (0) ◽  
pp. 107-116 ◽  
Author(s):  
R. Rahamimoff ◽  
S. D. Erulkar ◽  
E. Alnaes ◽  
H. Meiri ◽  
S. Rotshenker ◽  
...  
Keyword(s):  
Calcium Ions ◽  
Transmitter Release ◽  
Nerve Impulses

Transmitter release induced by injection of calcium ions into nerve terminals

1973 ◽  
Vol 183 (1073) ◽  
pp. 421-425 ◽  
Keyword(s):  
Nerve Terminal ◽  
Calcium Ions ◽  
Transmitter Release ◽  
Nerve Terminals ◽  
Presynaptic Nerve Terminal ◽  
External Fluid ◽  
Giant Synapse ◽  
Evoked Transmitter Release

Calcium ions injected into the presynaptic nerve terminal in the giant synapse of the squid, evoked transmitter release while similar doses of Mg and Mn were ineffective. The transmitter release induced by intracellular application was still observed when Ca was replaced in the external fluid by Mn, in spite of the fact that this abolished transmitter release in response to presynaptic depolarization.

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