Endotoxemia in febrile patients with hematological malignancies. Relationship of type of bacteremia, clinical findings and serum cytokine pattern

Infection ◽  
1997 ◽  
Vol 25 (1) ◽  
pp. 2-7 ◽  
Author(s):  
P. Engervall ◽  
M. Björkholm ◽  
Marta Granström ◽  
M. Kalin ◽  
B. Andersson
Keyword(s):  
Hematological Malignancies ◽  
Clinical Findings ◽  
Serum Cytokine ◽  
Cytokine Pattern ◽  
Relationship Of

scholarly journals Breast involvement of hematological malignancies: imaging and clinical findings

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Gamze Durhan ◽  
Figen Demirkazık
Keyword(s):  
Hematological Malignancies ◽  
Clinical Findings ◽  
Accurate Diagnosis ◽  
Radiological Findings ◽  
Breast Masses ◽  
Appropriate Treatment ◽  
Magnetic Resonance Imaging Mri ◽  
Type 3 ◽  
And Diffusion

Abstract Background Breast involvement of hematological malignancies is a very rare entity. Accurate diagnosis is essential for appropriate treatment. The aim of this study was to clarify the clinical and radiological findings of hematological malignancy breast involvement and to describe possible pitfalls in diagnosis. Results The images of 20 patients with breast involvement of hematological malignancies were retrospectively evaluated on ultrasonography, mammography, and magnetic resonance imaging (MRI) and the findings were reported. Bilaterality was seen only in cases with secondary involvement, and there was no marked difference between primary and secondary breast involvement of hematological malignancies. All patients underwent ultrasonography examination. According to ultrasonography, breast masses were most frequently irregular in shape (11/20, 55%) with non-circumscribed margins (11/20, 55%). Posterior acoustic enhancement was noted in 14 cases (70%). Posterior shadowing was not observed in any of the patients. Mammography was available in 10 patients. Microcalcification was not observed in any patient on mammography. MRI was available in four patients. Hyperintensity in T2-weighted images, type 2 or type 3 dynamic curve, and diffusion restriction were observed in all cases. Conclusions Hematological malignancies may mimic both benign breast lesions and breast carcinoma. Familiarity with the radiological features of hematological malignancies can help accurate diagnosis.

scholarly journals Serum cytokine pattern in young children with screening detected coeliac disease

2015 ◽  
Vol 179 (2) ◽  
pp. 230-235 ◽  
Author(s):  
S. Björck ◽  
S. R. Lindehammer ◽  
M. Fex ◽  
D. Agardh
Keyword(s):  
Young Children ◽  
Coeliac Disease ◽  
Serum Cytokine ◽  
Cytokine Pattern

Serum Cytokine Receptors in Ankylosing Spondylitis: Relationship to Inflammatory Markers and Endoplasmic Reticulum Aminopeptidase Polymorphisms

2010 ◽  
Vol 37 (9) ◽  
pp. 1907-1910 ◽  
Author(s):  
NIGIL HAROON ◽  
FLORENCE W.L. TSUI ◽  
BASIL CHIU ◽  
HING WO TSUI ◽  
ROBERT D. INMAN
Keyword(s):  
Endoplasmic Reticulum ◽  
Ankylosing Spondylitis ◽  
Disease Activity ◽  
Cytokine Receptor ◽  
Cytokine Receptors ◽  
Serum Cytokine ◽  
Markers Of Inflammation ◽  
Significant Difference ◽  
Cytokine Levels ◽  
Relationship Of

Objective.Endoplasmic reticulum aminopeptidase (ERAP)1 is associated with ankylosing spondylitis (AS) and is known to be involved in the clipping of the cytokine receptors interleukin 1 receptor II (IL-1RII), IL-6Rα, and tumor necrosis factor receptor I (TNFRI). We studied the relationship of these serum cytokine receptors and their corresponding cytokines to markers of inflammation and polymorphisms in ERAP1 and ERAP2 in patients with AS.Methods.Sera from patients with AS were assayed for TNF-α, IL-1, IL-6, sTNFRI, sIL-1RII, and sIL-6Rα by ELISA. Genotyping was performed for 3 AS-associated nonsynonymous single-nucleotide polymorphisms in the ERAP1 gene [rs27044(C/G), rs10050860(C/T), and rs30187(C/T)] and 1 in the ERAP2 gene [rs2549782(T/G)]. The serum cytokine and receptor levels were compared between the different genotype groups and correlated to markers of inflammation and disease activity.Results.Eighty patients with AS (21 women) with a mean Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) of 5.3 ± 2.4 were enrolled. There was a significant correlation of sTNFRI with C-reactive protein (CRP; R = 0.43, p < 0.001) and erythrocyte sedimentation rate (ESR; R = 0.30, p = 0.01) but not with BASDAI. Serum cytokine levels were undetectable in the majority of patients. There was no significant difference in serum cytokines or the soluble receptors between patients with the different ERAP1/ERAP2 polymorphisms and their haplotypes. Similarly, there was no relationship of the polymorphisms with the serum cytokine levels nor the cytokine-receptor ratio.Conclusion.Soluble TNFRI levels correlate with ESR and CRP in AS. The ERAP1 and ERAP2 polymorphisms associated with AS do not influence the serum cytokine receptor levels in patients with AS.

scholarly journals Nutrient intake and serum cytokine pattern in elderly people with heart failure

2008 ◽  
Vol 10 (4) ◽  
pp. 428-434 ◽  
Author(s):  
Girolamo Catapano ◽  
Claudio Pedone ◽  
Eleonora Nunziata ◽  
Alessandro Zizzo ◽  
Andrea Passantino ◽  
...  
Keyword(s):  
Heart Failure ◽  
Elderly People ◽  
Nutrient Intake ◽  
Serum Cytokine ◽  
Cytokine Pattern

The Relationship of HLA-A, B Status to the Clinical Findings and Autoimmunity in Coeliac Disease

1981 ◽  
pp. 173-182 ◽  
Author(s):  
Parveen Kumar ◽  
R. T. D. Oliver ◽  
D. P. O’Donoghue ◽  
A. Cudworth ◽  
M. Lancaster-Smith ◽  
...  
Keyword(s):  
Coeliac Disease ◽  
Clinical Findings ◽  
Relationship Of ◽  
The Relationship

scholarly journals Relationship of clinical findings in systemic lupus erythematosus to seroreactivity

1983 ◽  
Vol 26 (1) ◽  
pp. 45-51 ◽  
Author(s):  
Bruce M. Rothschild ◽  
John Verrier Jones ◽  
Carolyn Chesney ◽  
D. David Pifer ◽  
Lee D. Thompson ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Clinical Findings ◽  
Systemic Lupus ◽  
Relationship Of

scholarly journals Relationship of Molecular and Clinical Findings on Anaplasma phagocytophilum Involved in Natural Infections of Dogs

2011 ◽  
Vol 49 (12) ◽  
pp. 4413-4414 ◽  
Author(s):  
C. Silaghi ◽  
B. Kohn ◽  
A. Chirek ◽  
C. Thiel ◽  
I. Nolte ◽  
...  
Keyword(s):  
Anaplasma Phagocytophilum ◽  
Clinical Findings ◽  
Relationship Of
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