Some stability properties of large-scale baroclinic flows with nonlinear zonal current profile

1977 ◽  
Vol 33 (2) ◽  
pp. 55-60
Author(s):  
Jae Min Hyun
Keyword(s):  
Large Scale ◽  
Current Profile ◽  
Stability Properties ◽  
Zonal Current

scholarly journals BRANEart: identify stability strength and weakness regions in membrane proteins

2021 ◽  
Author(s):  
Sankar Basu ◽  
Simon S. Assaf ◽  
Fabian Teheux ◽  
Marianne Rooman ◽  
Fabrizio Pucci
Keyword(s):  
Membrane Proteins ◽  
Membrane Protein ◽  
Conformational Changes ◽  
Large Scale ◽  
Protein Structures ◽  
Accurate Method ◽  
Globular Proteins ◽  
Stability Properties ◽  
Overall Stability ◽  
The Stability

AbstractUnderstanding the role of stability strengths and weaknesses in proteins is a key objective for rationalizing their dynamical and functional properties such as conformational changes, catalytic activity, and protein-protein and protein-ligand interactions. We present BRANEart, a new, fast and accurate method to evaluate the per-residue contributions to the overall stability of membrane proteins. It is based on an extended set of recently introduced statistical potentials derived from membrane protein structures, which better describe the stability properties of this class of proteins than standard potentials derived from globular proteins. We defined a per-residue membrane propensity index from combinations of these potentials, which can be used to identify residues which strongly contribute to the stability of the transmembrane region or which would, on the contrary, be more stable in extramembrane regions, or vice versa. Large-scale application to membrane and globular proteins sets and application to tests cases show excellent agreement with experimental data. BRANEart thus appears as a useful instrument to analyze in detail the overall stability properties of a target membrane protein, to position it relative to the lipid bilayer, and to rationally modify its biophysical characteristics and function. BRANEart can be freely accessed from http://babylone.3bio.ulb.ac.be/BRANEart.

Is the Vertical Variability of the Ocean in Santos Bight, Brazil, Dominated by the Western Boundary Current Meanders?

2012 ◽  
Author(s):  
Wellington Ceccopieri ◽  
Ilson C. A. da Silveira
Keyword(s):  
Large Scale ◽  
Seawater Temperature ◽  
Great Part ◽  
Shelf Break ◽  
Data Series ◽  
Western Boundary ◽  
Baroclinic Mode ◽  
Oceanic Circulation ◽  
Current Profile ◽  
Boundary Current

The Brazil Current (CB) flows southwestward as vertically stratified and organized western boundary jet in the Brazilian shelf-break region ranging from 20–40° S, where the CB’s mass transport grows vertically. This geographical band show intense mesoescale activity due to passageway of eddies and meanders, superimposed over oceanic large-scale recirculation features which influence the oceanic circulation in the Santos Bight Pre-salt cluster area 300 km offshore. Based on 2-year observed data series of an oceanographic mooring array at Lula Field, and based on repeated hydrographic data (seawater temperature, salinity and N2 profiles) we used statistical and dynamical orthogonal modes in order to approach the local vertical current profile variability. We verified that it is 85 % explained by EOF-1. This variability is essentially of 1st baroclinic mode. Great part of it occupies the first 400–600 m water depth, with no predominant direction. We also found remarkable water column seasonal stratification. Albeit of relative weaker mean flows (0.1–0.2 m s−1), the study area is eddy dominated which are geostrophically adjusted to the 1st baroclinic mode. Furthermore, we observed that the significant directional variability over the São Paulo Plateau occurs far away from the mean current jets that flow parallel to the continental shelf-break geometry.

scholarly journals BRANEart: Identify Stability Strength and Weakness Regions in Membrane Proteins

2021 ◽  
Vol 1 ◽  
Author(s):  
Sankar Basu ◽  
Simon S. Assaf ◽  
Fabian Teheux ◽  
Marianne Rooman ◽  
Fabrizio Pucci
Keyword(s):  
Membrane Proteins ◽  
Membrane Protein ◽  
Conformational Changes ◽  
Large Scale ◽  
Protein Structures ◽  
Accurate Method ◽  
Globular Proteins ◽  
Stability Properties ◽  
Overall Stability ◽  
The Stability

Understanding the role of stability strengths and weaknesses in proteins is a key objective for rationalizing their dynamical and functional properties such as conformational changes, catalytic activity, and protein-protein and protein-ligand interactions. We present BRANEart, a new, fast and accurate method to evaluate the per-residue contributions to the overall stability of membrane proteins. It is based on an extended set of recently introduced statistical potentials derived from membrane protein structures, which better describe the stability properties of this class of proteins than standard potentials derived from globular proteins. We defined a per-residue membrane propensity index from combinations of these potentials, which can be used to identify residues which strongly contribute to the stability of the transmembrane region or which would, on the contrary, be more stable in extramembrane regions, or vice versa. Large-scale application to membrane and globular proteins sets and application to tests cases show excellent agreement with experimental data. BRANEart thus appears as a useful instrument to analyze in detail the overall stability properties of a target membrane protein, to position it relative to the lipid bilayer, and to rationally modify its biophysical characteristics and function. BRANEart can be freely accessed from http://babylone.3bio.ulb.ac.be/BRANEart.

Some comments about observations and image processing of comet 29P/Schwassmann-Wachmann 1

1999 ◽  
Vol 173 ◽  
pp. 243-248
Author(s):  
D. Kubáček ◽  
A. Galád ◽  
A. Pravda
Keyword(s):  
Image Processing ◽  
Large Scale ◽  
Harvard College ◽  
Oak Ridge ◽  
Large Scale Structures ◽  
Short Period Comet ◽  
Short Period ◽  
Scale Structures ◽  
Harvard College Observatory ◽  
Period Comet

AbstractUnusual short-period comet 29P/Schwassmann-Wachmann 1 inspired many observers to explain its unpredictable outbursts. In this paper large scale structures and features from the inner part of the coma in time periods around outbursts are studied. CCD images were taken at Whipple Observatory, Mt. Hopkins, in 1989 and at Astronomical Observatory, Modra, from 1995 to 1998. Photographic plates of the comet were taken at Harvard College Observatory, Oak Ridge, from 1974 to 1982. The latter were digitized at first to apply the same techniques of image processing for optimizing the visibility of features in the coma during outbursts. Outbursts and coma structures show various shapes.

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