Echocardiographic systolic time intervals in premature infants with patent ductus arteriosus

1980 ◽  
Vol 1 (2) ◽  
pp. 103-107 ◽  
Author(s):  
Gregory L. Johnson ◽  
Nirmala S. Desai ◽  
Carol M. Cottrill ◽  
Marianne Johnson ◽  
Jacqueline A. Noonan
PEDIATRICS ◽  
1984 ◽  
Vol 74 (6) ◽  
pp. 1069-1074
Author(s):  
François Heitz ◽  
Jean-Claude Fouron ◽  
Nicolaas H. van Doesburg ◽  
Harry Bard ◽  
François Teasdale ◽  
...  

M-mode echocardiographic features suggesting a patent ductus arteriosus are based on two groups of indirect criteria: dilation of the left cardiac cavities and changes of systolic time intervals. The reliability of the first group of criteria has been questioned in fluidlimited, mechanically ventilated preterm infants. The sensitivity of the systolic time intervals in the same circumstances is investigated. Twenty-three patients with a large patent ductus arteriosus were selected. Review of their echocardiograms shows that the sensitivity of the various criteria (expressed as percentage of positivity) was as follows: inversion of the ratio of left ventricular preejection period to right ventricular preejection period, 91.3%; left ventricular preejection period to left ventricular ejection time over right ventricular preejection period to right ventricular ejection time < 1, 83%; left atrium dilation, 74%; shortening of left ventricular preejection period, 70%; dilation of left ventricular internal dimensions in diastole, 65%; increase in left atrium/aorta, 52%; and decrease of left ventricular preejection period to left ventricular ejection time, 48%. Three criteria involving time intervals (left ventricular preejection period to right ventricular preejection period, left ventricular preejection period, and left ventricular preejection period to left ventricular ejection time) had 100% specificity. The lowest specificity was found with criteria involving the left atrium (left atrial to aortic root ratio 75% and left atrium 63%). It is concluded that study of systolic time intervals is a reliable means of detecting preterm infants with hemodynamically significant left-to-right shunt through a patent ductus arteriosus even if the infants are mechanically ventilated and fluid restricted.


1985 ◽  
Vol 19 (4) ◽  
pp. 345A-345A
Author(s):  
Cathy Hammerman ◽  
Elene Strates ◽  
Stuart Berger ◽  
William Zia ◽  
Abdul Aldousany

1993 ◽  
Vol 14 (3) ◽  
pp. 155-158 ◽  
Author(s):  
G. Michael Silberbach ◽  
Randall L. Imus ◽  
Robert W. McDonald ◽  
Kerri Andrilenas ◽  
Mary J. Rice ◽  
...  

PEDIATRICS ◽  
1985 ◽  
Vol 75 (3) ◽  
pp. 613-613

In the article "Value of Systolic Time Intervals in the Diagnosis of Large Patent Ductus Arteriosus in Fluid-Restricted and Mechanically Ventilated Preterm Infants" by Heitz et al (Pediatrics 1984;74:1069-1074), there is an error in the text. The last sentence of the second paragraph on page 1073 should reath All of these infants had a ratio of LPEP to RPEP > 1.


PEDIATRICS ◽  
1983 ◽  
Vol 72 (6) ◽  
pp. 864-871 ◽  
Author(s):  
Gregory L. Johnson ◽  
Gerard L. Breart ◽  
Michael H. Gewitz ◽  
Joel I. Brenner ◽  
Peter Lang ◽  
...  

As part of a multicenter collaborative study, M-mode echocardiograms were obtained shortly after birth on 3,559 premature infants with birth weight ≤1,750 g. Of these infants, 1,496 did not develop a cardiac murmur or other signs of a "hemodynamically significant" patent ductus arteriosus (PDA). Echocardiographic parameters from this "normal" group were compared with results obtained from 415 infants in whom PDA was diagnosed on the basis of clinical findings alone, irrespective of the echocardiogram (PDA group). The best discrimination between the two groups, when considering a single parameter, was provided by a left atrial to aortic root ratio (LA/AO) of 1.40, a left ventricular to aortic root ratio (LV/AO) of 2.10, or a left ventricular systolic time interval ratio (LPEP/LVET) of 0.27. Multivariate analysis demonstrated that better separation between the two groups occurred when the left atrial to aortic root ratio and the left ventricular systolic time interval ratio were considered jointly. Because of a large degree of overlap of all echocardiographic variables between the normal group and the group with PDA, the echocardiogram alone was not a good indicator of PDA. However, when used in conjunction with a priori estimates of the probability of PDA (based, for example, on birth weight and degree of respiratory disease), use of echocardiographic data was found to improve the detection of hemodynamically significant patent ductus arteriosus in premature infants.


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