Immunohistochemical study of the intestinal lymphoid tissue of germ-free mice

1968 ◽  
Vol 34 (1) ◽  
pp. 506-506
Author(s):  
P. A. Crabbé ◽  
H. Bazin ◽  
H. Eyssen ◽  
J. F. Heremans
Keyword(s):  
Lymphoid Tissue ◽  
Immunohistochemical Study ◽  
Germ Free ◽  
Intestinal Lymphoid Tissue

Studies of intestinal lymphoid tissue

1988 ◽  
Vol 412 (4) ◽  
pp. 365-370 ◽  
Author(s):  
M. N. Marsh ◽  
R. J. Leigh ◽  
D. E. Loft ◽  
G. V. Garner ◽  
D. B. Gordon
Keyword(s):  
Lymphoid Tissue ◽  
Intestinal Lymphoid Tissue

Immunohistochemical study of stromal and vascular components of tonsillar polyps: high endothelial venules as participants of the polyp’s lymphoid tissue

2011 ◽  
Vol 459 (1) ◽  
pp. 65-71 ◽  
Author(s):  
Icléia Barreto ◽  
Ana Flávia Costa ◽  
Marília Trierveiler Martins ◽  
Cristiane Furuse ◽  
Vera Cavalcanti de Araújo ◽  
...  
Keyword(s):  
Lymphoid Tissue ◽  
Immunohistochemical Study ◽  
High Endothelial Venules

Immunohistochemical Study of Lymphoid Tissue in HIV-infected Patients

2015 ◽  
pp. 184-200
Author(s):  
J. Audouin ◽  
G. Szekeres ◽  
A. Le Tourneau ◽  
S. Prevot ◽  
J. G. Fournier ◽  
...  
Keyword(s):  
Lymphoid Tissue ◽  
Immunohistochemical Study

scholarly journals A HISTOLOGICAL STUDY OF TYPHOID FEVER

1898 ◽  
Vol 3 (6) ◽  
pp. 611-638 ◽  
Author(s):  
F. B. Mallory
Keyword(s):  
Blood Vessels ◽  
Lymphoid Tissue ◽  
General Circulation ◽  
Intestinal Tract ◽  
Histological Study ◽  
The Body ◽  
Polymorphonuclear Leucocytes ◽  
Phagocytic Cells ◽  
Mesenteric Lymph Nodes ◽  
Intestinal Lymphoid Tissue

The typhoid bacillus produces a mild diffusible toxine, partly within the intestinal tract, partly within the blood and organs of the body. This toxine produces proliferation of endothelial cells which acquire for a certain length of time malignant properties. The new-formed cells are epithelioid in character, have irregular, lightly staining, eccentrically situated nuclei, abundant, sharply defined, acidophilic protoplasm, and are characterized by marked phagocytic properties. These phagocytic cells are produced most abundantly along the line of absorption from the intestinal tract, both in the lymphatic apparatus and in the blood-vessels. They are also produced by distribution of the toxine through the general circulation, in greatest numbers where the circulation is slowest. Finally, they are produced all over the body in the lymphatic spaces and vessels by absorption of the toxine eliminated from the blood-vessels. The swelling of the intestinal lymphoid tissue of the mesenteric lymph nodes, and of the spleen is due almost entirely to the formation of phagocytic cells. The necrosis of the intestinal lymphoid tissue is accidental in nature and is caused through occlusion of the veins and capillaries by fibrinous thrombi, which owe their origin to degeneration of phagocytic cells beneath the lining endothelium of the vessels. Two varieties of focal lesions occur in the liver: one consists of the formation of phagocytic cells in the lymph spaces and vessels around the portal vessels under the action of the toxine absorbed by the lymphatics; the other is due to obstruction of liver capillaries by phagocytic cells derived in small part from the lining endothelium of the liver capillaries, but chiefly by embolism through the portal circulation of cells originating from the endothelium of the blood-vessels of the intestine and spleen. The liver cells lying between the occluded capillaries undergo necrosis and disappear. Later the foci of cells degenerate and fibrin forms between them. Invasion with polymorphonuclear leucocytes is rare. Many of the phagocytic cells pass through the liver and lungs, and get into the general circulation. A few come from the abdominal lymphatics through the thoracic duct.

A Morphologic and Immunohistochemical Study of the Bronchus-associated Lymphoid Tissue of Pigs Naturally Infected with Mycoplasma hyopneumoniae

2003 ◽  
Vol 40 (4) ◽  
pp. 395-404 ◽  
Author(s):  
J. Sarradell ◽  
M. Andrada ◽  
A. S. Ramírez ◽  
A. Fernández ◽  
J. C. Gómez-Villamandos ◽  
...  
Keyword(s):  
T Lymphocytes ◽  
B Lymphocytes ◽  
Lamina Propria ◽  
Lymphoid Tissue ◽  
Mononuclear Cells ◽  
Plasma Cells ◽  
Immunohistochemical Study ◽  
Mycoplasma Hyopneumoniae ◽  
High Morbidity ◽  
Alveolar Septa

Porcine enzootic pneumonia (PEN), caused by Mycoplasma hyopneumoniae (Mh), has been described in pigs in all geographic areas. The disease is characterized by high morbidity and low mortality rates in intensive swine production systems. A morphologic and immunohistochemical study was done to determine the cellular populations present in lung parenchyma of infected pigs, with special attention to the bronchus-associated lymphoid tissue (BALT). Polyclonal and monoclonal antibodies were used for the detection of antigens of Mh, T lymphocytes (CD3+, CD4+, and CD8+), IgG+ or IgA+ lymphocytes, and cells containing lysozyme, S-100 protein, major histocompatibility complex class II antigen or myeloid-histiocyte antigen. Findings in lung tissues associated with Mh infection were catarrhal bronchointerstitial pneumonia, with infiltration of inflammatory cells in the lamina propria of bronchi and bronchioles and alveolar septa. Hyperplasia of mononuclear cells in the BALT areas was the most significant histologic change. The BALT showed a high morphologic and cellular organization. Macrophages and B lymphocytes were the main cellular components of germinal centers. T lymphocytes were primarily located in perifollicular areas of the BALT, lamina propria and within the airway epithelium, and plasma cells containing IgG or IgA at the periphery of the BALT, in the lamina propria of bronchi and bronchioles, in alveolar septa, and around bronchial submucosal glands. The hyperplastic BALT in PEN cases consisted of macrophages, dendritic cells, T and B lymphocytes, and IgG+ and IgA+ plasma cells. CD4+ cells predominated over CD8+ cells. Local humoral immunity appears to play an important role in the infection.

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