First-degree atrioventricular block in a young duodenal ulcer patient treated with a standard oral dose of ranitidine

1988 ◽  
Vol 24 (3-4) ◽  
pp. 237-242 ◽  
Author(s):  
G. Allegri ◽  
K. Pellegrini ◽  
G. Dobrilla
Keyword(s):  
Duodenal Ulcer ◽  
Oral Dose ◽  
Atrioventricular Block ◽  
Ulcer Patient ◽  
Duodenal Ulcer Patient

Assessment of the Duodenal Ulcer Patient as a Surgical Candidate

1970 ◽  
Vol 50 (3) ◽  
pp. 619-629 ◽  
Author(s):  
John W. Braasch ◽  
Ernesto Max ◽  
Richard E. Welling
Keyword(s):  
Duodenal Ulcer ◽  
Ulcer Patient ◽  
Duodenal Ulcer Patient

The Relation between Functioning Parietal Cell and Gastrin Cell Masses in Two Groups of Duodenal Ulcer Patients

1976 ◽  
Vol 50 (5) ◽  
pp. 375-383 ◽  
Author(s):  
D. J. Byrnes ◽  
Shiu Kum Lam ◽  
W. Sircus
Keyword(s):  
Duodenal Ulcer ◽  
Parietal Cell ◽  
Serum Gastrin ◽  
Acid Output ◽  
Ulcer Patient ◽  
Cell Mass ◽  
Inverse Correlation ◽  
Normal Subjects ◽  
Gastrin Cell ◽  
Before And After

1. Serum gastrin concentrations before and after a standardized meal were determined in twenty-eight patients with duodenal ulcer and in ten normal control subjects. 2. In response to pentagastrin, thirteen of the duodenal ulcer subjects secreted acid within the limits of normal and fifteen secreted in excess. 3. The differences in the basal serum gastrin concentrations between the three groups, normal subjects, acid ‘normosecretors’ and hypersecretors were not statistically significant but that of the hypersecretors was suggestively low. 4. The integrated gastrin response and peak gastrin responses to meals were higher in duodenal ulcer patients with normal acid secretion than in the hypersecretors but the values for the latter were not different from normal subjects. 5. Stabilization of intragastric pH by infusion into the antrum of sodium bicarbonate during the test meal response period did not alter these differences between the two ulcer patient groups. 6. A significant inverse correlation exists between the maximal acid output and the integrated gastrin response in both normal subjects and hypersecreting duodenal ulcer patients. 7. The evidence (a) supports the existence of an inverse relationship between the functioning parietal cell and gastrin cell masses, (b) shows the gastrin response in normosecreting ulcer subjects to be inappropriately high, and (c) suggests that excessive vagotonia exerts trophic effects upon both parietal cell mass and gastrin cell mass.

scholarly journals Relationship of Various Prognostic Factors with Outcome of Treatment of Chronic Duodenal Ulcer Perforation Patients

2014 ◽  
Vol 13 (2) ◽  
pp. 32-35
Author(s):  
Sakhawat Mahmud Khan ◽  
Meer Mahbubul Alam ◽  
Shahin Akhter ◽  
Didarul Alam
Keyword(s):  
Duodenal Ulcer ◽  
Prognostic Factors ◽  
Peritoneal Fluid ◽  
Ulcer Patient ◽  
Perforated Duodenal Ulcer ◽  
College Hospital ◽  
Major Health Problem ◽  
Ulcer Perforation ◽  
Chronic Duodenal Ulcer ◽  
Duodenal Ulcer Perforation

Background: In acute abdominal conditions, chronic duodenal ulcer  perforation is a very common surgical emergency that overwhelm the surgical ward throughout the year. Especially in the tropics and more in our country, peptic ulcer disease causes a major health problem. Objectives: To assess the usefulness of the prognostic factors in terms of morbidity and mortality in the treatment of perforated duodenal ulcer patient. Methods: This was a prospective study during the period from January 2003 to December 2003 in M.A.G. Osmani Medical College Hospital, Sylhet. The study included 100 cases of perforated chronic duodenal ulcer. Patients were randomly collected from all surgical units of SOMCH, Sylhet. Operation was done by simple closure with omental graft in all cases. Data analyzed by appropriate statistical method (Mean, SD & l2 test). Results: Highly significant relationship was found between increased age (>50 years) of patients with perforated duodenal ulcer and mortality (p<0.001). Lethality rate was higher in patients operated after 24 hours of onset of symptom in relation to patients operated within 24 hours of onset of symptom, (p<0.05). Different postoperative complications were prevalent in patients operated after 24 hours of onset of symptom, on the other hand complication rate was low in patients operated within 24 hours (p<0.001). There was also longer hospital stay in lately operated patients (more above median) than patients operated within 24 hrs (p<0.001). Mortality was higher in cases of purulent peritoneal fluid, where as it was nil in case of billous and serosanguinous fluid (p<0.001). More complications were developed in patients with purulent peritoneal fluid in comparison to billous and serosanguinous nature (p<0.001). There was more mortality in patients with preoperative shock in comparison with no features of shock (p<0.001). More complications were noted in patients with preoperative shock than in patients with no features of shock (p<0.01). Conclusion: Delayed operation, preoperative shock, more age and gross peritoneal sepsis bear a direct relationship with outcome of treatment chronic duodenal ulcer perforation patients.DOI: http://dx.doi.org/10.3329/cmoshmcj.v13i2.21060

Aladione® (Diftalone) in the Treatment of Subacute Thyroiditis

1977 ◽  
Vol 5 (5) ◽  
pp. 346-353
Author(s):  
Rajko Doleček
Keyword(s):  
Duodenal Ulcer ◽  
Oral Dose ◽  
Subacute Thyroiditis ◽  
Prolonged Administration ◽  
Inflammatory Drug ◽  
Daily Oral Dose ◽  
Average Treatment ◽  
Chronic Duodenal Ulcer ◽  
The Mean ◽  
Anti Inflammatory

During 1974 and 1975 thirty patients with subacute thyroiditis referred to us were treated with diftalone (Aladione®), a new non-steroidal anti-inflammatory drug, at a daily oral dose of 750 mg. The average treatment lasted 39 days (range 15-100), the mean age of the patients was 43·5 years (range: 22-70). The response to this therapy was prompt and excellent, in no patient was it necessary to switch to any other kind of treatment, such as the corticosteroids. The drug was tolerated very well although among our patients there were two diabetics on insulin and two patients with chronic duodenal ulcer. Following our experience in thirty patients we suggest that diftalone can be considered a treatment of choice in patients with subacute thyroiditis. We also think that during its prolonged administration leucocyte counts and transaminase levels should be regularly controlled.

scholarly journals To compare the efficacy of triple therapy with furazolidone, amoxicillin and omeprazole for two weeks and three weeks in the eradication of Helicobacter pylori in Bangladeshi duodenal ulcer patients

1970 ◽  
Vol 37 (3) ◽  
pp. 83-87 ◽  
Author(s):  
SK Saha ◽  
SK Saha ◽  
H Masud ◽  
N Islam ◽  
ASMA Raihan ◽  
...  
Keyword(s):  
Duodenal Ulcer ◽  
Helicobacter Pylori ◽  
Triple Therapy ◽  
Ulcer Patient ◽  
Duration Of Treatment ◽  
Helicobacter Pylori Eradication ◽  
Ulcer Disease ◽  
End Of Treatment ◽  
Group A ◽  
Group B

Helicobacter pylori eradication is the mainstay in the treatment of Helicobacter pylori associated peptic ulcer disease. Furazolidone was tried in several developing countries and showed good results in some trials. Increasing the duration of treatment has been shown to improve the eradication rate. This study was done to compare the efficacy of triple therapy for two weeks (Group–A) and three weeks (Group–B) consisting of omeprazole 20 mg b.d. amoxicillin 1gm b.d. and furazolidone 200 mg b.d. in the eradication of Helicobacter pylori in duodenal ulcer patient. A total of 70 duodenal ulcer patients with Helicobacter pylori infection were included in the study. Healing of duodenal ulcer was assessed three months after the end of treatment and at the same time Helicobacter pylori eradication assessed by Campylobacter Like Organism (CLO) test and histology. In group–A, duodenal ulcer was healed in 17(58.62%) patients and Helicobacter pylori was eradicated in 15(52%) patients. In group-B, duodenal ulcer was healed in 19(61.30%) patients and Helicobacter pylori was eradicated in 18(58%) patients. Healing of duodenal ulcer was not significantly different between two groups. Eradication of Helicobacter pylori was also not significantly different between two groups. DOI: http://dx.doi.org/10.3329/bmrcb.v37i3.9118 BMRCB 2011; 37(3): 83-87

INHIBITION OF NOCTURNAL ACID SECRETION IN DUODENAL ULCER BY ONE ORAL DOSE OF METIAMIDE

The Lancet ◽  
1974 ◽  
Vol 303 (7860) ◽  
pp. 693-694 ◽  
Author(s):  
G.J. Milton-Thompson ◽  
D.J.A. Jenkins ◽  
J.G. Williams ◽  
J.J. Misiewicz
Keyword(s):  
Duodenal Ulcer ◽  
Oral Dose ◽  
Acid Secretion
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