Toxicity studies on chlorinated guaiacols in the rat

Ih Chu; Leonard Ritter; Irma A. Marino; Algis P. Yagminas; David C. Villeneuve

doi:10.1007/bf02026945

Toxicity studies on chlorinated guaiacols in the rat

Bulletin of Environmental Contamination and Toxicology ◽

10.1007/bf02026945 ◽

1979 ◽

Vol 22 (1) ◽

pp. 293-296 ◽

Cited By ~ 5

Author(s):

Ih Chu ◽

Leonard Ritter ◽

Irma A. Marino ◽

Algis P. Yagminas ◽

David C. Villeneuve

Keyword(s):

Toxicity Studies ◽

Chlorinated Guaiacols

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Preclinical Toxicity Studies of Naltrexone

PsycEXTRA Dataset ◽

10.1037/e497452006-006 ◽

1976 ◽

Cited By ~ 2

Author(s):

Monique C. Braude ◽

J. Michael Morrison

Keyword(s):

Toxicity Studies

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Human liver cell cultivation for long-term in vitro toxicity studies in a miniaturized multi-compartment 3D bioreactor system

Zeitschrift für Gastroenterologie ◽

10.1055/s-0030-1269553 ◽

2011 ◽

Vol 49 (01) ◽

Author(s):

SA Hoffmann ◽

M Lübberstedt ◽

U Müller-Vieira ◽

D Knobeloch ◽

A Nüssler ◽

...

Keyword(s):

Liver Cell ◽

Human Liver ◽

In Vitro Toxicity ◽

Cell Cultivation ◽

Toxicity Studies ◽

Human Liver Cell ◽

Bioreactor System

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Acute and chronic toxicity studies on Polygonum glabrum in experimental animals

International Journal of Pharmacometrics and Integrated Biosciences ◽

10.26452/ijpib.v3i1.1216 ◽

2020 ◽

Vol 3 (1) ◽

pp. 7-10

Author(s):

Saravanakumar A ◽

Gandhimathi R

Keyword(s):

Chronic Toxicity ◽

Clinical Stage ◽

Herbal Medicines ◽

Plant Roots ◽

Root Extract ◽

Experimental Animals ◽

Toxicity Studies ◽

Acute And Chronic Toxicity ◽

Diuretic Agents

Polygonum glabrum is being used in traditional and folklore medicine to treat pneumonia and jaundice. Plant roots are used in ayurvedic preparations to treat fever and colic. The leaves are used as diuretic agents and process vermifuge action. Plant decoction is also used in the treatment of Rheumatism. Besides having many uses and folklore claims, herbal medicines are to be thoroughly investigated for their toxicity also. Therefore this work is being carried out to examine the toxicity of the drug and established dose is safe to use in the clinical stage. The current research studied the acute and chronic toxicity of Polygonum glabrum root extract in rats. It is proved that there was no change in any parameter tested both in acute and chronic toxicity, which means the extract is safe and non-toxic at the dose of 2g/kg also.

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