The Durability of Bilateral Carotid Endarterectomy

1995 ◽  
Vol 9 (1) ◽  
pp. 16-20 ◽  
Author(s):  
Phillip J. Rossi ◽  
R. James Valentine ◽  
Stuart I. Myers ◽  
Patrick T. Brillant ◽  
Arun Chervu ◽  
...  
1990 ◽  
Vol 78 (1) ◽  
pp. 25-31 ◽  
Author(s):  
T. L. Griffiths ◽  
S. J. Warren ◽  
A. D. B. Chant ◽  
S. T. Holgate

1. We have studied the carotid body contribution to hypoxic respiratory drive, using a hypoxic/hyperoxic switching technique, and the ventilatory response to intravenous infusion of adenosine, a recently described respiratory stimulant, in five patients with bilateral carotid endarterectomy. 2. The contribution made by the carotid bodies to total ventilatory drive during hypoxia varied from 2.5% to 45.9%. 3. The ventilatory response to adenosine infusion varied from a 7% decrease to a 25% increase in ventilation. 4. Those patients with intact hypoxic ventilatory drive showed respiratory stimulation, whereas of the two patients with attenuated chemoreflexes, one showed no stimulation and the other depression of ventilation in response to adenosine infusion. 5. We conclude that adenosine exerts its respiratory stimulant effect via an action on the peripheral chemoreceptors. This may coexist with a centrally mediated respiratory depression that is masked when the carotid bodies are intact.


1972 ◽  
Vol 175 (2) ◽  
pp. 268-273 ◽  
Author(s):  
Robert F. Hickey ◽  
William K. Ehrenfeld ◽  
F. Norman Hamilton ◽  
C. Philip Labson

Stroke ◽  
1995 ◽  
Vol 26 (3) ◽  
pp. 488-491 ◽  
Author(s):  
O. Ille ◽  
F. Woimant ◽  
A. Pruna ◽  
O. Corabianu ◽  
J. M. Idatte ◽  
...  

2009 ◽  
Vol 50 (1) ◽  
pp. 183-185 ◽  
Author(s):  
Devinder P. Singh ◽  
Antonio J.V. Forte ◽  
Michael B. Brewer ◽  
Roman Nowygrod

1986 ◽  
Vol 3 (2) ◽  
pp. 355-359 ◽  
Author(s):  
Torben Schroeder ◽  
Henrik Sillesen ◽  
Hans Christian Engell

1970 ◽  
Vol 6 (1) ◽  
pp. 41-44
Author(s):  
Rezwanul Hoque ◽  
Sabrina Sharmeen Husain ◽  
Zerzina Rahman ◽  
Ashia Ali ◽  
Mostafa Nuruzzaman ◽  
...  

Carotid Endarterectomy (CEA) performed in combination with coronary artery bypass grafting (CABG) have also increased steadily since Bernhard and colleague’s initial report in 1972. Coexistence of symptomatic coronary artery disease and significant carotid artery stenosis ranges from 3.4% to 22%. The incidence of postoperative stroke after CABG ranges from 0.7% to 5%. Coronary revascularization in a patient with internal carotid artery stenosis more than 50% is associated with a postoperative stroke rate of 6%, which increases significantly to more than 16% when stenosis is more than 90%. To reduce the potential risk for postoperative stroke after CABG in patients with significant or symptomatic carotid artery stenosis, many surgeons have advocated combined CABG with unilateral carotid endarterectomy. However, clinical experience with the concomitant approach is conflicting. On the basis of the long-term results, it is estimated that simultaneous carotid endarterectomy and myocardial revascularization in conjunction with cardiopulmonary bypass is a method safe enough to prefer its routine use with acceptable low operative risk and satisfactory long-term morbidity. The overall 30-day mortality of combined CABG with bilateral carotid endarterectomy was 6.1% and that was unrelated to primary cardiac or cerebrovascular events. Favorable outcome also supports the justification for performing concomitant coronary artery bypass grafting with bilateral carotid endarterectomies in selected patients. Key words: Carotid endarterectomy; Coronary Bypass Grafting. DOI: 10.3329/uhj.v6i1.7194University Heart Journal Vol.6(1) 2010 pp.41-44


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