Early MR detection of cortical and subcortical hypoxic-ischemic encephalopathy in full-term-infants

1994 ◽  
Vol 24 (8) ◽  
pp. 581-584 ◽  
Author(s):  
C. Christophe ◽  
A. Clercx ◽  
D. Blum ◽  
D. Hasaerts ◽  
C. Segebarth ◽  
...  
2017 ◽  
Vol 8 (6) ◽  
pp. 86-93
Author(s):  
Tat'yana V. Melashenko ◽  
Aleksandr V. Pozdnyakov ◽  
Viktor S. Lvov ◽  
Dmitry O. Ivanov

Perinatal hypoxic-ischemic encephalopathy (HIE) remains a major cause of neonatal mortality and development of severe neurological disorders that determine the quality of life of these children. In developed countries, the frequency of detection of hypoxic-ischemic encephalopathy (HIE) among full-term newborns is 1-6 per 1.000 live births. In our country, hypoxic-ischemic brain damage is observed in 15-30% of full-term newborns. The term HIE is a clinical diagnosis combining neurological disorders and biochemical changes caused by perinatal HI (hypoxiа-ischemia). The pattern of acute brain damage depends on the degree of cerebral maturity, the severity and duration of hypoxiа-ischemia. The most vulnerable regions are the structures of the brain with high level of metabolism. Such structures in term infants include cortical neurons and neurons of basal nuclei, a subcortical white matter. MRI allows to diagnose brain lesions in term infants in the acute period of HIE. Safety, non-invasiveness and large diagnostic capabilities of MRI allow this method to be considered the gold standard of neuroimaging in neonatology. In this review we described the main MRI patterns of brain injury in term neonates following HIE.


2004 ◽  
Vol 32 (1) ◽  
pp. 131-136 ◽  
Author(s):  
Diego Gazzolo ◽  
Emanuela Marinoni ◽  
Romolo Di Iorio ◽  
Matteo Bruschettini ◽  
Maria Kornacka ◽  
...  

2016 ◽  
Vol 55 (6) ◽  
pp. 297
Author(s):  
Susanti Halim ◽  
I Gusti Nyoman Made Suwarba ◽  
I Made Kardana

ingtool used to determine developmental and electrical problemsin the brain. A history of severe asphyxia is a risk factor for thesebrain problems in infants.Objective To evaluate the prevalence of abnormal EEGs infull term neonates and to assess for an association with severeasphyxia, hypoxic ischemic encephalopathy (HIE), and spontaneousdelivery.Methods This cross-sectional study was conducted at thePediatric Outpatient Department of Sanglah Hospital, Denpasar,from November 2013 to January 2014. Subjects were fullterminfants aged 1 month who were delivered and/or hospitalized atSanglah Hospital. All subjects underwent EEG. The EEGs wereinterpreted by a pediatric neurology consultant, twice, with aweek interval between readings. Clinical data were obtainedfrom medical records. Association between abnormal ECG andsevere asphyxia were analyzed by Chi-square and multivariablelogistic analyses.Results Of 55 subjects, 27 had a history of severe asphyxia and 28were vigorous babies. Forty percent (22/55) of subjects had abnormalEEG findings, 19/22 of these subjects having history of severeasphyxia, 15/22 had history of hypoxic-ischemic encephalopathy(HIE), and 20/22 were delievered vaginally. There were strongcorrelations between the prevalence of abnormal EEG and historyof severe asphyxia, HIE, and spontaneous delivery.Conclusion Prevalence of abnormal EEG among full-term neonatesreferred to neurology/growth development clinic is around40%, with most of them having a history of severe asphyxia. AbnormalEEG is significantly associated to severe asphyxia, HIE, andspontaneous delivery.


2012 ◽  
Vol 33 (1) ◽  
pp. 15-20 ◽  
Author(s):  
J C Barrera-de León ◽  
R Cervantes-Munguía ◽  
C Vásquez ◽  
M A Higareda-Almaraz ◽  
A Bravo-Cuellar ◽  
...  

NeoReviews ◽  
2021 ◽  
Vol 22 (4) ◽  
pp. e275-e278
Author(s):  
Emman Dabaja ◽  
Deniz Altinok ◽  
Mallory O’Niel ◽  
Beena G. Sood

2008 ◽  
Vol 153 (3) ◽  
pp. 375-378.e2 ◽  
Author(s):  
William Oh ◽  
Rebecca Perritt ◽  
Seetha Shankaran ◽  
Matthew Merritts ◽  
Edward F. Donovan ◽  
...  

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