Risk factors for nosocomial sepsis in newborn intensive and intermediate care units

1996 ◽  
Vol 155 (4) ◽  
pp. 315-322 ◽  
Author(s):  
M. L. Moro ◽  
A. De Toni ◽  
I. Stolfi ◽  
M. P. Carrieri ◽  
M. Braga ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intermediate Care ◽  
Nosocomial Sepsis

Risk factors for nosocomial sepsis in newborn intensive and intermediate care units

1996 ◽  
Vol 155 (4) ◽  
pp. 315-322 ◽  
Author(s):  
M. L. Moro ◽  
A. De Toni ◽  
I. Stolfi ◽  
M. P. Carrieri ◽  
M. Braga ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intermediate Care ◽  
Nosocomial Sepsis

scholarly journals Risk factors for transfer from respiratory intermediate CARE unit to INTENSIVE CARE unit in COVID-19

2021 ◽  
Author(s):  
Enrico Buonamico ◽  
Vitaliano Nicola Quaranta ◽  
Esterina Boniello ◽  
Michela Dimitri ◽  
Valentina Di Lecce ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Intermediate Care ◽  
Intermediate Care Unit

Nosocomial Sepsis and its Risk Factors: A Cross-Sectional Study in a Neonatal Intensive Care Unit

2019 ◽  
Vol 2 (1) ◽  
pp. 52-59
Author(s):  
Sunil Kumar Yadav ◽  
SP Yadav ◽  
P Kanodia ◽  
N K Bhatta ◽  
R R Singh ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Mechanical Ventilation ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Nosocomial Sepsis

Introduction: Nosocomial sepsis is a common and serious infection of neonates who are admitted in intensive care unit. They lead to significant morbidity and mortality in both developed and resource limited countries. The neonatal intensive care unit (NICU) is a suitable environment for disseminating the infections and, hence, needs preventive intervention. The study was carried out to determine the risk factors for nosocomial sepsis in neonatal intensive care unit. Material and Methods: This was a cross-sectional study conducted in a seven bedded teaching and referral hospital NICU. All neonates in NICU who did not have any sign of infection at admission and remained hospitalized for at least 48 hours were observed. Nosocomial sepsis was diagnosed according to the CDC criteria. Risk factors for nosocomial sepsis were analyzed with Chi-square test and Logistic regression model. P-value of <0.05 was considered significant. Results: Low birth weight (both preterm and IUGR) and mechanical ventilation were found to be related with nosocomial sepsis. Conclusions: Low birth weight and mechanical ventilation were the most important risk factors fornosocomial sepsis.

#21: Risk Factors and Clinical Characteristics of Stenotrophomonas Maltophilia Infections in Neonates & Children from Day 1 to 21-Year Old Between the Years 2008 to 2020

2021 ◽  
Vol 10 (Supplement_2) ◽  
pp. S8-S9
Author(s):  
Ashraf Abdlhemid ◽  
Margaret R Hammerschlag
Keyword(s):  
Risk Factors ◽  
Mechanical Ventilation ◽  
Stenotrophomonas Maltophilia ◽  
Antimicrobial Agents ◽  
Opportunistic Infections ◽  
Treatment Guidelines ◽  
Intrinsic Resistance ◽  
Beta Lactamases ◽  
Nosocomial Sepsis ◽  
Elevated Liver Enzymes

Abstract Background Stenotrophomonas maltophilia is a ubiquitous organism associated with opportunistic infections. In the immunocompromised host, increasing prevalence and severity of illness is observed, particularly opportunistic bloodstream infections and pneumonia syndromes. S. maltophilia is intrinsically resistant to most currently available broad-spectrum antibiotics, including carbapenems and beta-lactams. This intrinsic resistance is due to the presence of chromosomally expressed beta-lactamases, L1 (a metallo-carbapenemase), and L2 (an extended-spectrum beta-lactamases), which together can hydrolyze nearly all betalactam antibiotics including carbapenems. In vitro activity is observed with tetracyclines and fluoroquinolones, but resistance can be rapidly induced mainly due to efflux pumps. Trimethoprim/sulfamethoxazole (TMP-SMX) generally is considered the treatment of choice for S. maltophilia infection, although consideration of S. maltophilia in treatment guidelines is sparse. Additionally, a recent study suggests that S. maltophilia susceptibility to TMP-SMX may be decreasing globally, due in part to acquired antibiotic resistance. Though historically identified as a cause of nosocomial infections, communityonset infections increasingly are being reported. From 1996 to 2016, S. maltophilia was commonly isolated from patients hospitalized with pneumonia and bloodstream infection (BSI), and the incidence of S. maltophilia infection is increasing Methods A retrospective analysis of characteristics and outcomes in patients with S. maltophilia–positive cultures were conducted using the Healthbridge EHR. Study Population This retrospective matched case control study was carried out in neonates with S. maltophilia infections at UHB DOWNSTATE MEDICAL CENTER NICU and Pediatric Department between 2008 and 2020. To identify the case patients, we reviewed the admission and medical records of patients and records from the Microbiology Department in the study period. Control patients were selected from the patients who admitted for at least 72 hours and had pneumonia and/or nosocomial sepsis caused by pathogens other than S. maltophilia. To determine the risk factors for S. maltophilia infections among 35 case patients were compared with 35 control patients. Medical charts of all infants with positive cultures for S. maltophilia and control cases were reviewed for birth weight; gestational age; delivery type; postnatal age at hospitalization; prolonged rupture of membranes; invasive procedures (mechanical ventilation, intubation, urinary catheter, umbilical catheter); duration of mechanical ventilation (day); exposure to antimicrobial agents (aminoglycosides, carbapenems, cephalosporins, penicillins); administration of total parenteral nutrition (TPN); duration of TPN; histamine 2 (H2) blockers; exposure to steroids; cholestasis; elevated liver enzymes; death; sepsis-related death; and duration of hospitalization. All the risk factors for infection were calculated before the onset of infection in both groups. Results in progress Conclusions:

Analysis of risk factors for nosocomial sepsis in surgical patients

2000 ◽  
Vol 87 (8) ◽  
pp. 1076-1081 ◽  
Author(s):  
C. Fariñas-Álvarez ◽  
M. C. Fariñas ◽  
C. Fernández-Mazarrasa ◽  
J. Llorca ◽  
D. Casanova ◽  
...  
Keyword(s):  
Risk Factors ◽  
Surgical Patients ◽  
Nosocomial Sepsis

scholarly journals Pressure ulcers’ incidence, preventive measures, and risk factors in neonatal intensive care and intermediate care units

2018 ◽  
Vol 15 (4) ◽  
pp. 571-579 ◽  
Author(s):  
Pablo García-Molina ◽  
Evelin Balaguer-López ◽  
Francisco Pedro García-Fernández ◽  
María de los Ángeles Ferrera-Fernández ◽  
José María Blasco ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intensive Care ◽  
Neonatal Intensive Care ◽  
Pressure Ulcers ◽  
Preventive Measures ◽  
Intermediate Care

Epidemiological Differences Between Sepsis Syndrome With Bacteremia and Culture-Negative Sepsis

2000 ◽  
Vol 21 (10) ◽  
pp. 639-644 ◽  
Author(s):  
Concepción Fariñas-Álvarez ◽  
M. Carmen Fariñas ◽  
Carlos Fernández-Mazarrasa ◽  
Javier Llorca ◽  
Miguel Delgado-Rodríguez
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Intensive Care ◽  
Conditional Logistic Regression ◽  
Tertiary Care ◽  
Positive Culture ◽  
Sepsis Syndrome ◽  
Icu Stay ◽  
Nosocomial Sepsis ◽  
Culture Negative

AbstractObjective:To explore the association of putative disease markers and potential risk factors with the nosocomial sepsis syndrome.Design:Prospective case-control study matched for gender, age, and length of preinfection hospital stay.Setting:1,200-bed tertiary-care center in Spain.Patients:Cases were selected using the sepsis syndrome criteria of the American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference and were divided into three groups: sepsis with bacteremia (109 cases), sepsis with positive culture other than blood (122 cases), and sepsis with negative culture (115 cases without documented infection but with sepsis syndrome, clinically suspected infection, and empirical antibiotic treatment). Controls were randomly selected from the daily list of inpatients. Data were collected prospectively. Crude and multiple-risk-factor-adjusted odds ratios and their 95% confidence intervals were computed using conditional logistic regression analysis.Results:Presence of coma in the 48 hours before sepsis, intensive care unit (ICU) stay, and decreased serum albumin levels at admission were common epidemiological markers identified for the three groups of cases. Having a central venous catheter was the main healthcare-related risk factor for bacteremia. ICU stay and nasogastric tube were the main risk factors for sepsis with positive culture other than blood. Coma within 48 hours before sepsis and the need of intensive care were the only two markers identified for culture-negative sepsis.Conclusion:Culture-negative sepsis does not behave like culture-positive sepsis, and this may imply that implementation of preventive measures to decrease the risk of bacteremia may not decrease the risk of sepsis syndrome.

scholarly journals Risk Factors for Fractures in Children Hospitalized in Intensive and Intermediate Care Units

2017 ◽  
Vol 7 (7) ◽  
pp. 395-402 ◽  
Author(s):  
Ian S. Zenlea ◽  
Patrice Melvin ◽  
Susanna Y. Huh ◽  
Nilesh Mehta ◽  
Suzanne J. Reidy ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intermediate Care ◽  
Fractures In Children
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