Calcitonin and its antinociceptive activity: Animal and human investigations 1975–1992

1994 ◽  
Vol 41 (3-4) ◽  
pp. 121-131 ◽  
Author(s):  
P. C. Braga
Keyword(s):  
Antinociceptive Activity ◽  
Activity Animal

Lacistema pubescens Mart.: A species with antinociceptive activity

2017 ◽  
Author(s):  
J Conegundes ◽  
F Fernandes Maria ◽  
R Mendes ◽  
N Pinto ◽  
J Silva ◽  
...  
Keyword(s):  
Antinociceptive Activity

scholarly journals Anti-nociceptive and anti-inflammatory effects of an aqueous extract of blended leaves of Ocimum gratissimum and Psidium guajava

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Akinyinka O. Alabi ◽  
Abayomi M. Ajayi ◽  
Osarume Omorogbe ◽  
Solomon Umukoro
Keyword(s):  
Acetic Acid ◽  
Aqueous Extract ◽  
Psidium Guajava ◽  
Antinociceptive Activity ◽  
Hot Plate ◽  
Hot Plate Test ◽  
Promising Alternative ◽  
Plate Test ◽  
Ocimum Gratissimum ◽  
Anti Inflammatory

Abstract Background To investigate the antinociceptive and anti-inflammatory activities of aqueous extract of a blended mixture of dried leaves of Ocimum gratissimum and Psidium guajava, a traditional analgesic drug polyherbal (TADP) used as a remedy for pain-related conditions. Methods Antinociceptive activity of TADP (100, 200 and 400 mg/kg) was evaluated in the hot plate test and acetic acid-induced nociception in mice while the anti-inflammatory was evaluated in carrageenan-induced paw oedema in rats. Levels of nitrite, myeloperoxidase, glutathione and malondialdehyde were assayed in carrageenan-induced paw tissue. Results TADP (200 and 400 mg/kg) significantly prolong the latency time in the hot-plate test. TADP (100–400 mg/kg) produced a dose-dependent significant inhibition of the acetic-acid induced abdominal constriction. The antinociceptive activity of TADP in the presence of naloxone and atropine was not reversed whereas yohimbine and glibenclamide significantly reversed it. TADP (100, 200 and 400 mg/kg) significantly reduced the swelling in the carrageenan-induced oedema model and also produced a reduction in the nitrite and myeloperoxidase level. TADP (400 mg/kg) significantly reduced malondialdehyde concentration and increase glutathione level in the carrageenan-induced rat paw. TADP significantly decrease the number of cellular infiltrates in the histopathological assessment. Conclusion These results indicate that polyherbal product containing blended leaves of Ocimum gratissimum and Psidium guajava possess antinociceptive and anti-inflammatory properties, hence represents a promising alternative remedy in inflammation-induced pain.

Nalbuphine could decrease the rewarding effect induced by tramadol in mice while enhancing its antinociceptive activity

2015 ◽  
Vol 758 ◽  
pp. 11-15 ◽  
Author(s):  
Rasha Abdel-Ghany ◽  
Mahmoud Nabil ◽  
Mohamed Abdel-Aal ◽  
Waleed Barakat
Keyword(s):  
Antinociceptive Activity ◽  
Rewarding Effect

ChemInform Abstract: 4-Amino-5-vinyl-3(2H)-pyridazinones and Related Compounds: Synthesis and Evaluation of Antinociceptive Activity.

ChemInform ◽  
2010 ◽  
Vol 33 (36) ◽  
pp. no-no
Author(s):  
Vittorio Dal Piaz ◽  
Stefano Pieretti ◽  
Claudia Vergelli ◽  
Maria Carla Castellana ◽  
Maria Paola Giovannoni
Keyword(s):  
Antinociceptive Activity ◽  
Related Compounds

Synthesis and Antinociceptive Activity of (2-Benzazolon-3-yl)propionamide Derivatives

2001 ◽  
Vol 334 (1) ◽  
pp. 17-20 ◽  
Author(s):  
T. ?nkol ◽  
S. Ito ◽  
E. Yildirim ◽  
K. Erol ◽  
M. F. Sahin
Keyword(s):  
Antinociceptive Activity

Antinociceptive activity of the pyranocoumarin seselin in mice

Fitoterapia ◽  
2006 ◽  
Vol 77 (7-8) ◽  
pp. 574-578 ◽  
Author(s):  
Vilma Lima ◽  
Caio B. Silva ◽  
Jair Mafezoli ◽  
Mirna M. Bezerra ◽  
M. Odorico Moraes ◽  
...  
Keyword(s):  
Antinociceptive Activity

Chemical Composition, Acute Toxicity, and Antinociceptive Activity of the Essential Oil of a Plant Breeding Cultivar of Basil (Ocimum basilicumL.)

Planta Medica ◽  
2010 ◽  
Vol 77 (08) ◽  
pp. 825-829 ◽  
Author(s):  
Antônio Venâncio ◽  
Alexandre Onofre ◽  
Amintas Lira ◽  
Péricles Alves ◽  
Arie Blank ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Acute Toxicity ◽  
Essential Oil ◽  
Plant Breeding ◽  
Antinociceptive Activity

Investigations on the antinociceptive activity of crude extracts from Croton cajucara leaves in mice

Fitoterapia ◽  
2002 ◽  
Vol 73 (2) ◽  
pp. 116-120 ◽  
Author(s):  
A.R. Campos ◽  
F.A.A. Albuquerque ◽  
V.S.N. Rao ◽  
M.A.M. Maciel ◽  
A.C. Pinto
Keyword(s):  
Antinociceptive Activity ◽  
Crude Extracts ◽  
Croton Cajucara

Synthesis, antinociceptive activity and opioid receptor profiles of 3-(octahydro-1H-pyrano- and -thiopyrano[4,3-c]pyridin-8a-yl)phenols

1989 ◽  
pp. 1177 ◽  
Author(s):  
David E. Bays ◽  
Dearg S. Brown ◽  
David J. Belton ◽  
Jane E. Lloyd ◽  
Andrew B. McElroy ◽  
...  
Keyword(s):  
Opioid Receptor ◽  
Antinociceptive Activity
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