Foetal growth retardation in the rat following chronic exposure to the inhalation anaesthetic enflurane

1978 ◽  
Vol 34 (10) ◽  
pp. 1332-1333 ◽  
Author(s):  
W. D. B. Pope ◽  
T. V. N. Persaud
Keyword(s):  
Growth Retardation ◽  
Chronic Exposure ◽  
Foetal Growth ◽  
Inhalation Anaesthetic

Amniotic fluid alkaline ribonuclease activity: an indicator of foetal growth retardation and anencephaly

1984 ◽  
Vol 143 (2) ◽  
pp. 157-162 ◽  
Author(s):  
Paul K. Buamah ◽  
Paul H. Scott ◽  
Andrew W. Skillen ◽  
Peter Taylor ◽  
A. Milford-Ward
Keyword(s):  
Amniotic Fluid ◽  
Growth Retardation ◽  
Ribonuclease Activity ◽  
Foetal Growth ◽  
Alkaline Ribonuclease

SOMATOMEDIN-LIKE ACTIVITY IN PLASMA AFTER FOETAL HYPOPHYSECTOMY OR NEPHRECTOMY AND IN EXPERIMENTAL INTRA-UTERINE GROWTH RETARDATION IN SHEEP

1979 ◽  
Vol 83 (1) ◽  
pp. 119-127 ◽  
Author(s):  
J. FALCONER ◽  
J. M. FORBES ◽  
I. C. HART ◽  
J. S. ROBINSON ◽  
G. D. THORBURN
Keyword(s):  
Growth Hormone ◽  
Gestational Age ◽  
Growth Retardation ◽  
Costal Cartilage ◽  
Maternal Plasma ◽  
Plasma Samples ◽  
Foetal Growth ◽  
Uterine Growth ◽  
The Mean ◽  
Intra Uterine Growth Retardation

SUMMARY Plasma samples from pregnant ewes and their foetuses during the last quarter of gestation were assayed for somatomedin-like activity (SLA) using the porcine costal cartilage assay. In maternal plasma, the mean potency (compared with pooled serum from six sheep) was 0·84 ± 0·05 (s.e.m.) units/ml (n = 15). Somatomedin-like activity in the plasma of five control foetuses (0·91 ± 0·1 units/ml) was similar to the maternal levels and did not change with gestational age. After foetal hypophysectomy the SLA in foetal plasma (0·37 ± 0·05 units/ ml, n = 4) was significantly less than in control animals. In two nephrectomized foetuses, the mean SLA in plasma (0·08 and 0·51 units/ml respectively) was less than in control animals. Retardation of intra-uterine foetal growth was induced by removal of endometrial caruncles before pregnancy in four sheep. The SLA in plasma from these foetuses was 0·38 ± 0·05 units/ml (P< 0·01 v. control animals). The results suggest that SLA in the foetus may be important in the regulation of foetal growth, but they also indicate that factors other than growth hormone may be important in the control of SLA in foetal plasma.

Persistent chlorinated pesticides and intra-uterine foetal growth retardation: a possible association

2003 ◽  
Vol 76 (1) ◽  
pp. 75-80 ◽  
Author(s):  
M. Siddiqui ◽  
S. Srivastava ◽  
S. Srivastava ◽  
P. Mehrotra ◽  
N. Mathur ◽  
...  
Keyword(s):  
Growth Retardation ◽  
Chlorinated Pesticides ◽  
Foetal Growth

scholarly journals Congenital infection of SARS-CoV-2 with intrauterine foetal death: a clinicopathological study with molecular analysis

2021 ◽  
Author(s):  
Emmanuelle Lesieur ◽  
Julia Torrents ◽  
Frédéric Fina ◽  
Christine Zandotti ◽  
Julie Blanc ◽  
...  
Keyword(s):  
Growth Retardation ◽  
Tissue Damage ◽  
Congenital Infection ◽  
Molecular Techniques ◽  
Foetal Death ◽  
Foetal Growth ◽  
Hepatocellular Damage ◽  
Foetal Tissue ◽  
Clinicopathological Study ◽  
Variant Analysis

Abstract Observations of vertical transmission of SARS-CoV-2 infection from mother to foetus have recently been described in the literature. However, the consequences of such transmission, whether foetal or neonatal, are poorly understood. From a case of in utero foetal death at 24 +2 weeks of gestation that occurred seven days after the diagnosis of symptomatic SARS-CoV-2 infection in the mother, we isolated the incriminating virus by immunochemistry and molecular techniques in several foetal tissues, with a variant analysis of the SARS-CoV-2 genome. Moreover, the foetal demise could be explained by the presence of placental histological lesions, such as histiocytic intervillositis and trophoblastic necrosis, in addition to foetal tissue damage. We observed mild foetal growth retardation and visceral damage to the liver, causing hepatocellular damage and haemosiderosis. To the best of our knowledge, this is the first report in the literature of foetal demise secondary to maternal-foetal transmission of SARS-CoV-2 with a congenital infection and a pathological description of placental and foetal tissue damage. SARS-CoV-2 was identified in both specimens by three independent techniques (immunochemistry, RT-qPCR and RT-dPCR). Furthermore, the incriminating variant has been identified.

scholarly journals Melatonin improves diabetes-induced foetal growth retardation in rats

2015 ◽  
Vol 18 (1) ◽  
pp. 42-47
Author(s):  
LA Olayaki ◽  
AO Soladoye ◽  
OO Ojo
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Enzymes ◽  
Growth Retardation ◽  
Intraperitoneal Administration ◽  
Pharmaceutical Journal ◽  
Diabetic Rats ◽  
Pregnant Rats ◽  
Enzymes Activities ◽  
Foetal Growth ◽  
Antioxidant Enzymes Activities

The aim of the present study was to investigate the effect of oral melatonin administration on foetal growth retardation, utero-placental antioxidant enzymes activities and lipid peroxidation in experimental diabetic rats. Twenty pregnant rats were divided into four groups of five rats each. Diabetes mellitus was induced by a single intraperitoneal administration of 120mg/kg body weight of alloxan. From gestational day 5 to 19, 5mg/kg and 10mg/kg of oral melatonin were administered to the rats with clearly manifested gestational diabetes. On the 19th day of gestation, the rats were sacrificed by cervical dislocation and placental, foetal and uterine tissues were harvested for estimation of tissue glutathione peroxidase (GPx) activity and malondialdehyde (MDA) levels. Foetal weight, foetal size, placental and plasma glucose were also determined. Results showed that, in diabetic rats, foetal growth retardation was associated with a significant reduction in placental and uterine antioxidant enzymes (GPx) activities (P<0.001) and increased lipid peroxidation as evidenced by raised MDA concentration (P< 0.05). Treatment with oral melatonin significantly improved the foetal weight, placental and uterine antioxidant enzymes activities as well as reduced lipid peroxidation, without affecting the degree of hyperglycaemia. Effects of melatonin on foetal growth are presumed to be dependent on its ability to improve uteroplacental antioxidant enzymes activities and reduce lipid peroxidation.Bangladesh Pharmaceutical Journal 18(1): 42-47, 2015

Tinzaparin for the treatment of foetal growth retardation: An open-labelled randomized clinical trial

2018 ◽  
Vol 170 ◽  
pp. 38-44 ◽  
Author(s):  
Anette Tarp Hansen ◽  
Puk Sandager ◽  
Mette Ramsing ◽  
Olav B. Petersen ◽  
Jannie D. Salvig ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Growth Retardation ◽  
Foetal Growth

scholarly journals Racial disparities in the association of foetal growth retardation to childhood blood pressure

2005 ◽  
Vol 20 (8) ◽  
pp. 1592-1597 ◽  
Author(s):  
Stephen G. Rostand ◽  
Suzanne P. Cliver ◽  
Robert L. Goldenberg
Keyword(s):  
Blood Pressure ◽  
Racial Disparities ◽  
Growth Retardation ◽  
Foetal Growth
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