Pathologisch-anatomische und experimentelle Untersuchungen zur Frage des Diabetes insipidus und der Beziehungen zwischen Tuber cinereum und Hypophyse

1924 ◽  
Vol 252 (2-3) ◽  
pp. 734-747 ◽  
Author(s):  
Clara Kary
Keyword(s):  
Diabetes Insipidus ◽  
Tuber Cinereum ◽  
Experimentelle Untersuchungen

HYPOTHALAMIC CONTROL OF PITUITARY GONADOTROPHINS

1961 ◽  
Vol 22 (1) ◽  
pp. 107-117 ◽  
Author(s):  
C. C. GALE ◽  
S. M. McCANN
Keyword(s):  
Diabetes Insipidus ◽  
Median Eminence ◽  
Oestrogen Therapy ◽  
Milk Ejection ◽  
Pregnant Rats ◽  
Tuber Cinereum ◽  
Severe Diabetes ◽  
Hypothalamic Control ◽  
Electrolytic Lesions ◽  
Experienced Difficulty

SUMMARY Impairments in gestation, parturition, and milk ejection were produced when electrolytic lesions were placed in the median eminence of the tuber cinereum of pregnant rats at various stages of gestation. Thus, uterine implantation of ova was blocked in 65% of rats following placement of lesions on day 1 of gestation, and implantation of ova was induced in these animals by administration of oestrogen. When lesions localized to the caudal median eminence were placed on days 4–9, implantation was not blocked but abortion-resorption resulted in 90% of cases. Replacement studies during pregnancy in rats with lesions in the caudal median eminence suggest that (1) all aborting rats were deficient in gonadotrophins necessary for secretion of oestrogen, and (2) half of them were deficient in luteotrophin as well. (That is, luteotrophin had no replacement value, while oestrogen therapy permitted maintenance of gestation in 54% of cases, and oestrogen plus progesterone allowed 100% to remain pregnant.) In rats receiving lesions on days 7–9 and maintaining gestation to term, 32% of those with severe diabetes insipidus experienced difficulty during delivery. Placement of lesions after day 13 impaired neither gestation nor parturition. The observation that most rats with lesions were able to deliver their litters normally but were unable to eject milk following suckling stimuli suggests that oxytocin is not essential for parturition in this species. Most of the rats with lesions failed to resume oestrous cycles; of the few showing return of normal or irregular cycles, the majority failed to mate.

Effect of ADH on Rat Renal Papilla, an Ultrastructural and Cytochemical Study

1973 ◽  
Vol 31 ◽  
pp. 410-411
Author(s):  
C. N. Sun ◽  
H. J. White ◽  
E. J. Towbin
Keyword(s):  
Electron Microscopy ◽  
Diabetes Insipidus ◽  
Renal Papilla ◽  
Milk Diet ◽  
Intercellular Spaces ◽  
Cytochemical Study ◽  
Collecting Tubule ◽  
Concentrate Urine ◽  
Staining Techniques ◽  
Collecting Tubules

Diabetes insipidus and compulsive water drinking are representative of two categories of antidiuretic hormone (ADH) lack. We studied a strain of rats with congenital diabetes insipidus homozygote (DI) and normal rats on an isocaloric fortified dilute milk diet. In both cases, the collecting tubules could not concentrate urine. Special staining techniques, Alcian Blue-PAS for light microscopy and lanthanum nitrate for electron microscopy were used to demonstrate the changes in interstitial mucopolysaccharides (MPS). The lanthanum staining was done according to the method of Khan and Overton.Electron microscopy shows cytoplasmic lesions, vacules, swelling and degenerating mitochondria and intercellular spaces (IS) in the collecting tubule cells in DI and rats on milk diet.

Abstract #813 Adult Atypical Sellar Teratoid Tumor Presenting as Diabetes Insipidus

2018 ◽  
Vol 24 ◽  
pp. 178-179
Author(s):  
Sabrina Huq ◽  
Mahalakshmi Honasoge ◽  
Ebru Sulanc
Keyword(s):  
Diabetes Insipidus

Abstract #60: Pituitary Teratoma Presenting with Diabetes Insipidus

2004 ◽  
Vol 10 ◽  
pp. 22
Author(s):  
Carolyn Narvacan-Montano ◽  
Thelma D. Crisostomo
Keyword(s):  
Diabetes Insipidus

Abstract #306: Diabetes Insipidus and ACTH Deficiency Following Subarachnoid Hemorrhage

2006 ◽  
Vol 12 ◽  
pp. 60
Author(s):  
Jann M. Johnston ◽  
Camille Marie Buonocore ◽  
Adrianna Katarzyna Wegrecki ◽  
Imran Mohammed
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Diabetes Insipidus ◽  
Acth Deficiency

Kongenitaler nephrogener Diabetes insipidus – Fallbericht und Diskussion

2009 ◽  
Vol 66 (11) ◽  
pp. 765-768
Author(s):  
Curzio Solcà ◽  
Anja Kruse
Keyword(s):  
Diabetes Insipidus

Die Krankengeschichte eines Patienten mit angeborenem renalen Diabetes insipidus wird dargestellt. Die Pathogenese und therapeutischen Modalitäten werden diskutiert.

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