Brucellosis and parenteral drug abuse

1984 ◽  
Vol 3 (4) ◽  
pp. 319-320 ◽  
Author(s):  
J. Romero-Vivas ◽  
A. Guerrero ◽  
L. M. Buzon ◽  
J. Berenguer ◽  
J. Martinez-Beltran ◽  
...  
2020 ◽  
Vol 12 (3) ◽  
pp. 422-427
Author(s):  
Sohun Awsare ◽  
David Chirikian ◽  
Forshing Lui

Botulism is an acute paralytic disease caused by botulinum neurotoxin (BoNT)-mediated inhibition of neurosignaling at the neuromuscular junction. BoNTs are produced by gram positive, anaerobic, spore-forming bacteria from the genus <i>Clostridium,</i>most commonly<i> Clostridium botulinum</i>. Over the last decade, a previously uncommon form of botulism, wound botulism, has increased in prevalence possibly due to the rise in parenteral drug abuse. A 53-year-old patient with a history of drug abuse presents to a rural emergency department with rapidly progressing lower extremity weakness over the past few days. He reports a recent heroin injection into right buttock and diffuse skin-popping scarring was observed throughout. The patient was treated with heptavalent botulinum antitoxin obtained from the Center for Disease Control and Prevention (CDC). A right thigh abscess culture was positive for<i> Clostridium tertium</i>, a left hip abscess culture was positive for methicillin-susceptible <i>Staphylococcus aureus</i> (MSSA), and blood culture confirmed multi-microbial bacteremia caused by <i>Staphylococcus epidermidis</i> and <i>Streptococcus mitis</i>. Serum analysis was positive for BoNT type A from a suspected concurrent<i> Clostridium botulinum</i> infection as <i>C. tertium</i> is not known to produce BoNT type A. This case report highlights the importance of early antitoxin treatment for patients with suspected wound botulism.


1986 ◽  
Vol 30 (5) ◽  
pp. 314-320 ◽  
Author(s):  
Joseph B. Michelson ◽  
Howard S. Robin ◽  
Robert A. Nozik

1995 ◽  
Vol 52 (6) ◽  
pp. 503-505 ◽  
Author(s):  
Samir Bassily ◽  
Richard G. Hibbs ◽  
Magdy D. Samaan ◽  
Kenneth C. Hyams ◽  
Randa A. Fouad

1993 ◽  
Vol 29 (6) ◽  
pp. 1052-1054 ◽  
Author(s):  
Jeffrey B. Pardes ◽  
Vincent Falanga ◽  
Francisco A. Kerdel

1985 ◽  
Vol 100 (3) ◽  
pp. 408-410 ◽  
Author(s):  
Suzanne K. Swan ◽  
Renee A. Wagner ◽  
Joseph P. Myers ◽  
Albert B. Cinelli

2004 ◽  
Vol 73 (4) ◽  
pp. 302-304 ◽  
Author(s):  
A.O. Mireku-Boateng ◽  
Cordell Nwokeji

2006 ◽  
Vol 40 (10) ◽  
pp. 28
Author(s):  
JOHN R. BELL
Keyword(s):  

2007 ◽  
Vol 40 (22) ◽  
pp. 22-23
Author(s):  
SHARON WORCESTER
Keyword(s):  

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