Intrafamiliar long-time epidemiology of drug-resistance factors and other plasmids in fecalE. coli

1986 ◽  
Vol 42 (1) ◽  
pp. 97-98
Author(s):  
C. Sutter ◽  
G. Lebek
Keyword(s):  
Drug Resistance ◽  
Resistance Factors ◽  
Long Time

Further observations on the genetic transfer of drug resistance in Eimeria maxima

Parasitology ◽  
1977 ◽  
Vol 74 (2) ◽  
pp. 205-213 ◽  
Author(s):  
L. P. Joyner ◽  
C. C. Norton
Keyword(s):  
Drug Resistance ◽  
Zygote Formation ◽  
Genetic Transfer ◽  
Resistance Factors ◽  
Eimeria Maxima

Experiments are described which support the view that, in Eimeria maxima, drug resistance factors are transferred at zygote formation. The phenomenon occurred between infections which were initiated by the inoculation of merozoites. It also took place between variants of the same, but not between different species. Transference of drug resistance wsa not affected by the treatment of the chicks with acriflavine.

scholarly journals A Compendium of Information on the Lysosome

2021 ◽  
Vol 9 ◽  
Author(s):  
Nadia Bouhamdani ◽  
Dominique Comeau ◽  
Sandra Turcotte
Keyword(s):  
Drug Resistance ◽  
Scientific Knowledge ◽  
Targeted Therapies ◽  
Cancer Drug ◽  
Functional Changes ◽  
The Past ◽  
Cancer Drug Resistance ◽  
Anti Cancer ◽  
Long Time ◽  
Signaling Organelles

For a long time, lysosomes were considered as mere waste bags for cellular constituents. Thankfully, studies carried out in the past 15 years were brimming with elegant and crucial breakthroughs in lysosome research, uncovering their complex roles as nutrient sensors and characterizing them as crucial multifaceted signaling organelles. This review presents the scientific knowledge on lysosome physiology and functions, starting with their discovery and reviewing up to date ground-breaking discoveries highlighting their heterogeneous functions as well as pending questions that remain to be answered. We also review the roles of lysosomes in anti-cancer drug resistance and how they undergo a series of molecular and functional changes during malignant transformation which lead to tumor aggression, angiogenesis, and metastases. Finally, we discuss the strategy of targeting lysosomes in cancer which could lead to the development of new and effective targeted therapies.

Transferred drug-resistance in Eimeria maxima

Parasitology ◽  
1975 ◽  
Vol 71 (3) ◽  
pp. 385-392 ◽  
Author(s):  
L. P. Joyner ◽  
C. C. Norton
Keyword(s):  
Drug Resistance ◽  
The Other ◽  
Drug Resistant ◽  
Resistance Factors ◽  
Eimeria Maxima ◽  
Series Of Experiments ◽  
Resistant Strains ◽  
Drug Resistant Strains

A series of experiments is described in which two drug-resistant strains of Eimeria maxima were passaged together in untreated chicks. The resultant oocysts were then inoculated into chicks treated with both drugs. When strains resistant to methyl benzoquate and sulphaquinoxaline or clopidol and sulphaquinoxaline were used the resultant infections were not controlled by the double treatment, indicating the acquisition of resistance factors by one strain from the other. When strains resistant to clopidol and methyl benzoquate were used the phenomenon was not observed.

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