On the significance of the rostral process of bipolar neurosecretory cells in the caudal neurosecretory system of certain catfishes

1979 ◽  
Vol 35 (11) ◽  
pp. 1459-1460
Author(s):  
C. B. L. Srivastava ◽  
H. C. Srivastava
Keyword(s):  
Neurosecretory Cells ◽  
Neurosecretory System ◽  
Caudal Neurosecretory System

Bursting properties of caudal neurosecretory cells in the flounder Platichthys flesus, in vitro

2001 ◽  
Vol 204 (15) ◽  
pp. 2733-2739 ◽  
Author(s):  
M. J. Brierley ◽  
A. J. Ashworth ◽  
J. R. Banks ◽  
R. J. Balment ◽  
C. R. McCrohan
Keyword(s):  
Cell Activity ◽  
Extracellular Recording ◽  
Neurosecretory Cells ◽  
Neurosecretory System ◽  
Repetitive Firing ◽  
Physiological Status ◽  
Cycle Period ◽  
Caudal Neurosecretory System ◽  
Bursting Activity

SUMMARY Bursting activity in type 1 Dahlgren cells was studied using intra- and extracellular recording from an in vitro preparation of the caudal neurosecretory system of the euryhaline flounder. 45% of cells showed spontaneous bursts of approximately 120s duration and 380s cycle period. Similar bursts were triggered by short duration (<5s) depolarising or hyperpolarising pulses. Cells displayed a characteristic depolarising after potential, following either an action potential with associated afterhyperpolarisation, or a hyperpolarising current pulse. This depolarising after potential was related to a ‘sag’ potential, which developed during the hyperpolarising pulse. Both the depolarising after potential and the sag potential occurred only in cells at more depolarised (<60mV) holding potentials. In addition, the amplitude of the depolarising after potential was dependent on the amplitude and the duration of the hyperpolarising pulse. The depolarising after potential following action potentials may provide a mechanism for facilitating repetitive firing during a burst. Extracellular recording revealed similar bursting in individual units which was not, however, synchronised between units. Spontaneous bursting activity recorded both intra- and extracellularly was inhibited by application of a known neuromodulator of the system, 5-hydroxytryptamine. This study provides a basis for investigating the relationship between physiological status, Dahlgren cell activity and neuropeptide secretion.

Régulations aminergique et cholinergique du système caudal neurosécréteur de l'omble de fontaine, Salvelinus fontinalis, en relation avec l'osmo-iono-regulation

1983 ◽  
Vol 61 (12) ◽  
pp. 2856-2867 ◽  
Author(s):  
Laurent Gauthier ◽  
Céline Audet ◽  
Gaston Chevalier
Keyword(s):  
Brook Trout ◽  
Salvelinus Fontinalis ◽  
Light And Electron Microscopy ◽  
Neurosecretory Cells ◽  
Regulatory Function ◽  
Synthetic Activity ◽  
Neurosecretory System ◽  
Neurosecretory Material ◽  
Electron Microscopic ◽  
Caudal Neurosecretory System

The innervation of the caudal neurosecretory system of the brook trout, Salvelinus fontinalis, was studied under light and electron microscopy in order to characterize its nature, distribution, and regulatory function over the activity of the caudal neurosecretory cells. A dual innervation of the cell bodies and axons of neurosecretory cells was disclosed. One type of axosomatic connection exhibited small lucent vesicles and large dense-cored granules. These boutons were identified as monoaminergic since they appeared depleted after reserpine treatment and they were selectively labeled with 5-OH-dopamine. In fish exposed to demineralized water, reserpine induced a condition that stimulated the synthetic activity of caudal neurosecretory cells, a clear reduction of this activity, according to morphometric (cell and nucleus diameters) and ultrastructural criteria (dimensions of the Golgi complex). By comparison, no significant variation of the synthetic activity was noted in freshwater-adapted trout treated with reserpine. A second type of innervation was also identified as cholinergic by histochemical localization of acetylcholinesterase. Electron microscopic analysis also revealed axosomatic and axoaxonic cholinergic synaptic connections with characteristic small 500-Å diameter lucent vesicles. The injection of fenitrothion, an anticholinesterase agent, enhanced discharge of neurosecretory material from axonal endings of caudal cells while the synthetic activity did not appear to be modified. Our findings suggest an important role of aminergic and cholinergic controls over the response of the caudal neurosecretory system of Salvelinus fontinalis during hyperosmotic adaptation.

Activation of the peptidergic neurosecretory system in Diphyllobothrium dendriticum (Cestoda: Pseudophyllidea)

Parasitology ◽  
1981 ◽  
Vol 83 (2) ◽  
pp. 243-247 ◽  
Author(s):  
Margaretha K. S. Gustafsson ◽  
Marianne C. Wikgren
Keyword(s):  
Neurosecretory Cells ◽  
Final Host ◽  
Fish Host ◽  
Neurosecretory System ◽  
Weak Reaction ◽  
Diphyllobothrium Dendriticum ◽  
Large Numbers ◽  
Short Times

SUMMARYThe activation of the peptidergic neurosecretory system in Diphyllobothrium dendriticum was studied following cultivation of plerocercoids for short times in vitro and in vivo. In the plerocercoid the neurosecretory cells gave a very weak reaction with paraldehyde fuchsin (PAF). After cultivation for 1 h large numbers of neurosecretory cells filled with PAF-positive granules were evident. The significance of the activation of the neurosecretory system during the transfer of the worm from the cold-blooded fish host to the warm-blooded final host is discussed.

Fish caudal neurosecretory system: A model for the study of neuroendocrine secretion

2007 ◽  
Vol 153 (1-3) ◽  
pp. 243-250 ◽  
Author(s):  
Catherine R. McCrohan ◽  
Weiqun Lu ◽  
Matthew J. Brierley ◽  
Louise Dow ◽  
Richard J. Balment
Keyword(s):  
Neurosecretory System ◽  
Caudal Neurosecretory System ◽  
System A

scholarly journals Urotensin receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

2019 ◽  
Vol 2019 (4) ◽  
Author(s):  
Anthony P. Davenport ◽  
Stephen A. Douglas ◽  
Alain Fournier ◽  
Adel Giaid ◽  
Henry Krum ◽  
...  
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Neurosecretory System ◽  
Urotensin Ii ◽  
High Sequence Identity ◽  
Caudal Neurosecretory System ◽  
Amino Acid Peptide ◽  
Related Peptide ◽  
Human Sequence ◽  
Mature Mouse

The urotensin-II (U-II) receptor (UT, nomenclature as agreed by the NC-IUPHAR Subcommittee on the Urotensin receptor [26, 36, 89]) is activated by the endogenous dodecapeptide urotensin-II, originally isolated from the urophysis, the endocrine organ of the caudal neurosecretory system of teleost fish [7, 88]. Several structural forms of U-II exist in fish and amphibians. The goby orthologue was used to identify U-II as the cognate ligand for the predicted receptor encoded by the rat gene gpr14 [20, 62, 68, 70]. Human urotensin-II, an 11-amino-acid peptide [20], retains the cyclohexapeptide sequence of goby U-II that is thought to be important in ligand binding [53, 11]. This sequence is also conserved in the deduced amino-acid sequence of rat urotensin-II (14 amino-acids) and mouse urotensin-II (14 amino-acids), although the N-terminal is more divergent from the human sequence [19]. A second endogenous ligand for the UT has been discovered in rat [83]. This is the urotensin II-related peptide, an octapeptide that is derived from a different gene, but shares the C-terminal sequence (CFWKYCV) common to U-II from other species. Identical sequences to rat urotensin II-related peptide are predicted for the mature mouse and human peptides [32]. UT exhibits relatively high sequence identity with somatostatin, opioid and galanin receptors [89].

Neurohormones from Fish Tails: The Caudal Neurosecretory System

1985 ◽  
pp. 533-552 ◽  
Author(s):  
HOWARD A. BERN ◽  
DAVID PEARSON ◽  
BRETT A. LARSON ◽  
RICHARD S. NISHIOKA
Keyword(s):  
Neurosecretory System ◽  
Caudal Neurosecretory System
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