Risk factors for fatal pulmonary interstitial emphysema in neonates

1990 ◽  
Vol 149 (7) ◽  
pp. 493-495 ◽  
Author(s):  
C. Morisot ◽  
N. Kacet ◽  
M. C. Bouchez ◽  
V. Rouland ◽  
J. P. Dubos ◽  
...  
2020 ◽  
Author(s):  
Judith Behnke ◽  
Anita Windhorst ◽  
Frank Oehmke ◽  
Lars Daniel Berthold ◽  
Klaus‐Peter Zimmer ◽  
...  

2021 ◽  
Vol 10 (7) ◽  
pp. 205846012110342
Author(s):  
Akihiro Nakamata ◽  
Nanae Tsuchiya ◽  
Tetsuhiro Miyara ◽  
Murasaki Shiotani ◽  
Shinji Gibo ◽  
...  

Background Subpleural pulmonary interstitial emphysema is defined as the air in the subpleural portion of the lung, and the clinical relevance is not well understood. Purpose to evaluate the frequency, temporal course, risk factors, and clinical significance of subpleural pulmonary interstitial emphysema (PIE) in patients with pneumomediastinum resulting from ruptured alveoli and other causes. Material and Methods This was a retrospective study of 130 patients with pneumomediastinum on CT between January 2009 and December 2019 at 2 hospitals. Patients were divided into 3 groups as follows: spontaneous pneumomediastinum ( n = 101), pneumomediastinum due to blunt trauma ( n = 16), and pneumomediastinum due to another known cause ( n = 13). The frequencies of radiographic features (subpleural PIE, peribronchovascular PIE, pneumothorax, pulmonary fibrosis, and emphysematous changes) between the 3 groups were compared by the χ2 or Kruskal–Wallis test. Odds ratios were calculated to evaluate candidate risk factors for subpleural and peribronchovascular PIE. Results Subpleural PIE was observed in 0%, 15.8%, and 31.3% of patients with pneumomediastinum due to another cause, spontaneous mediastinum, and blunt trauma, respectively. In most patients, subpleural PIE resolved spontaneously (85.7% within 8 days). Two patients with pulmonary fibrosis showed recurrent subpleural PIE on follow-up. Young age showed increased risk for subpleural PIE (odds ratio [OR] 0.9, 95% confidence interval [CI] 0–0.99). Conclusion Subpleural PIE was only detected in patients with pneumomediastinum due to ruptured alveoli and resolved spontaneously and rapidly. Subpleural PIE may be one route the air from ruptured alveoli to the mediastinum.


CHEST Journal ◽  
1993 ◽  
Vol 104 (2) ◽  
pp. 647-648 ◽  
Author(s):  
Tai-Shion Lee ◽  
Kuo-Tong Liao

The Lancet ◽  
1993 ◽  
Vol 341 (8860) ◽  
pp. 1603 ◽  
Author(s):  
E.L. Abrahamson ◽  
M. Viswanath ◽  
I.Z. Kovar ◽  
S. Al Jawad

PEDIATRICS ◽  
1977 ◽  
Vol 60 (3) ◽  
pp. 273-281
Author(s):  
John L. Watts ◽  
Ronald L. Ariagno ◽  
June P. Brady

To determine pulmonary function abnormalities in patients with neonatal bronchopulmonary dysplasia (BPD), we measured distribution of ventilation by nitrogen washout, minute and tidal volume, and arterial and alveolar gases in three groups of ten preterm infants with similar birth weights (mean = 1,340 g) and gestational ages (mean = 30.3 weeks). Infants in group A were never artificially ventilated, those in group B were ventilated but had no subsequent BPD, and those in group C were ventilated and developed BPD. Infants with BPD had severe maldistribution of ventilation (pulmonary clearance delay 223% versus 47% and 60% for groups A and B). They had decreased tidal volumes (5.3 ml versus 7.0 and 6.2 ml) and higher respiratory rates (60/min versus 47 and 48) but similar minute volumes. They also had increased Paco2 (53.6 torr versus 41.9 and 43.4 torr) and increased arterial-alveolar carbon dioxide gradients (6.8 torr versus 3.1 and 1.8 torr). There was no statistically significant difference between groups B and C for the time spent in fractional inspired oxygen > 0.40 and > 0.60, or the time ventilated or intubated, or the incidence of patent ductus arteriosus. Early pulmonary interstitial emphysema was much more common in the infants who subsequently developed BPD (eight of ten versus two of ten, P < .01).


1986 ◽  
Vol 22 (3) ◽  
pp. 189-192
Author(s):  
V. Y. H. YU ◽  
P. Y. WONG ◽  
B. BAJUK ◽  
W. SZYMONOWICZ

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