Antibiotic activity of organic compounds and their average quasi-valence number

1978 ◽  
Vol 34 (5) ◽  
pp. 633-635 ◽  
Author(s):  
V. Ajdačić ◽  
V. Veljković
Keyword(s):  
Organic Compounds ◽  
Antibiotic Activity ◽  
Valence Number

The Tempo and mode(S) of Prebiotic Evolution

1997 ◽  
Vol 161 ◽  
pp. 419-429 ◽  
Author(s):  
Antonio Lazcano
Keyword(s):  
Origin Of Life ◽  
Organic Compounds ◽  
Biological Evolution ◽  
Current Evidence ◽  
Early Diversification ◽  
Time Period ◽  
The Galaxy ◽  
History Of ◽  
Widespread Phenomenon ◽  
The Origin Of Life

AbstractDifferent current ideas on the origin of life are critically examined. Comparison of the now fashionable FeS/H2S pyrite-based autotrophic theory of the origin of life with the heterotrophic viewpoint suggest that the later is still the most fertile explanation for the emergence of life. However, the theory of chemical evolution and heterotrophic origins of life requires major updating, which should include the abandonment of the idea that the appearance of life was a slow process involving billions of years. Stability of organic compounds and the genetics of bacteria suggest that the origin and early diversification of life took place in a time period of the order of 10 million years. Current evidence suggest that the abiotic synthesis of organic compounds may be a widespread phenomenon in the Galaxy and may have a deterministic nature. However, the history of the biosphere does not exhibits any obvious trend towards greater complexity or «higher» forms of life. Therefore, the role of contingency in biological evolution should not be understimated in the discussions of the possibilities of life in the Universe.

Inactivation of Antiplasmin and Complement C1 in Human Plasma Rendered Fibrinolytic by Synthetic Organic Compounds

1963 ◽  
Vol 10 (01) ◽  
pp. 151-163 ◽  
Author(s):  
Kurt N von Kaulla
Keyword(s):  
Human Plasma ◽  
Organic Compounds ◽  
Bovine Serum ◽  
Fibrinolytic Activity ◽  
Plasma Generation ◽  
Synthetic Organic Compounds

SummaryCertain synthetic organic compounds induce upon dissolution marked fibrinolytic activity in human plasma, reduce the antiplasmin titer of human or bovine serum and destroy the complement C1 of human plasma. Generation of fibrinolytic activity and reduction of antiplasmin are concentration-depending time reactions. Destruction of complement C1 occurs almost instantaneously. Minor molecular modifications abolish all three activities of the compounds.

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