W-Sex chromatin fluorescence in snakes

1972 ◽  
Vol 28 (2) ◽  
pp. 228-229 ◽  
Author(s):  
W. Beçak ◽  
Maria Luiza Beçak
Keyword(s):  
Sex Chromatin ◽  
Chromatin Fluorescence

SEX-CHROMATIN FLUORESCENCE IN HUMAN AMNIOTIC-FLUID CELLS

The Lancet ◽  
1971 ◽  
Vol 298 (7726) ◽  
pp. 709-710 ◽  
Author(s):  
AsitB Mukherjee ◽  
PeggyY Blattner ◽  
HaroldM Nitowsky
Keyword(s):  
Amniotic Fluid ◽  
Human Amniotic Fluid ◽  
Sex Chromatin ◽  
Amniotic Fluid Cells ◽  
Chromatin Fluorescence

SEX-CHROMATIN FLUORESCENCE IN HAIR-ROOT CELLS

The Lancet ◽  
1971 ◽  
Vol 298 (7717) ◽  
pp. 220 ◽  
Author(s):  
Clara Goday ◽  
J. Egozcueuy ◽  
Emilia Bafall
Keyword(s):  
Hair Root ◽  
Root Cells ◽  
Sex Chromatin ◽  
Chromatin Fluorescence

Spontaneous Haemophilia in a Female

1960 ◽  
Vol 04 (03) ◽  
pp. 369-375 ◽  
Author(s):  
E. H Braun ◽  
David B. Stollar
Keyword(s):  
Family History ◽  
Bleeding Time ◽  
Dental Extraction ◽  
White Girl ◽  
Complete Family ◽  
Normal Limits ◽  
Sex Chromatin ◽  
History Of ◽  
Generation Test

SummaryA case of haemophilia in a young white girl is described. There was a history of bleeding from birth. The thromboplastin generation test was grossly abnormal and A. H. G. levels were below 1%. Bleeding time and capillary morphology was within normal limits. Dental extraction after transfusion caused almost uncontrollable haemorrhage.A complete family history was obtained for four generations. There was no case of a “bleeder” amongst these.The girl’s apparent sex was confirmed by sex chromatin studies.

Y Chromosomes in Male Psychiatric Patients above 180 cm. Tall

1968 ◽  
Vol 114 (517) ◽  
pp. 1589-1590 ◽  
Author(s):  
Johannes Nielsen
Keyword(s):  
Chromosome Number ◽  
State Hospital ◽  
Psychiatric Patients ◽  
Chromosome Analysis ◽  
Y Chromosomes ◽  
Sex Chromatin ◽  
Male Patients

All male patients above 180 cm. tall who were resident in the Århus State Hospital on 13 April, 1966, were registered: they numbered 42 out of the total of 440 resident males (8 · 1 per cent.). One patient, a 78-year-old man, died before chromosome analysis was made. Sex-chromatin analysis was made on Feulgenstained buccal smears and chromosome analysis was made on leucocyte cultures according to the method described by Moorhead et al. (1960), slightly modified. Not less than 25 metaphases were counted, at least 15 metaphases with the modal figure and all metaphases with a chromosome number deviating from the modal figures were analysed.

The ratio of male to female embryos as determined by the sex chromatin

1960 ◽  
Vol 79 (3) ◽  
pp. 504-509 ◽  
Author(s):  
Vincent Tricomi ◽  
David Serr ◽  
George Solish
Keyword(s):  
Sex Chromatin ◽  
Male To Female

ON THE SEX CHROMATIN AND THE SEX CHROMOSOMES IN SEXUAL ANOMALIES IN MAN RELATION TO ORIGIN OF THE SEX CHROMATIN

1960 ◽  
Vol 34 (1_Suppla) ◽  
pp. S633-S644 ◽  
Author(s):  
Melvin M. Grumbach ◽  
Akira Morishima ◽  
Ernest H. Y. Chu
Keyword(s):  
Sex Chromosomes ◽  
Sex Chromatin

CLINICAL CONFERENCE

PEDIATRICS ◽  
1957 ◽  
Vol 20 (4) ◽  
pp. 740-746
Author(s):  
Melvin M. Grumbach
Keyword(s):  
Sex Difference ◽  
Sex Chromosome ◽  
Good Evidence ◽  
Polymorphonuclear Neutrophils ◽  
Vaginal Mucosa ◽  
Simple Method ◽  
X Chromosomes ◽  
Cytologic Examination ◽  
Sex Development ◽  
Sex Chromatin

Dr. Grumbach: Barr and associates have demonstrated that in the human the majority of somatic cells of females contain a conspicuous, heterochromatic mass of chromatin in the resting nuclei. Their discovery of a sex-difference in intermitotic nuclei of a number of vertebrate species, including man, has provided a relatively simple method for assessing the sex-chromosome constitution. This chromatin mass is about 1 micron in diameter and often plano-convex in configuration. It is usually located against the inner surface of the nuclear membrane and contains desoxyribonucleic acid. In males, a comparable chromatin mass is rarely found, never in more than a few per cent of the nuclei. There is good evidence that this so-called "sexchromatin" represents the fusion of heterochromatic portions of two X-chromosomes. The sex chromatin can be conveniently determined by examination of specimens of skin obtained by biopsy (Fig. 1). Recently, more practical methods for determining cytologic sex have been described employing smears from readily available tissues, such as the oral and vaginal mucosa (Fig. 2) and the blood. Davidson and Smith have shown that there is a sex difference in the morphology of polymorphonuclear neutrophils. Cytologic examination of chromosomal sex has provided an important tool for the investigation of anomalies of sex development. Apart from its ancillary role in diagnosis, cytologic examination of sex chromatin has made a significant contribution to our understanding of the disordered development in these afflictions. However, the results of this determination should not be regarded as an especial indication of the psychosexual orientation of patients with such abnormalities, nor, in the case of infants, of the sex to which they should be assigned.

Sex Chromatin Survey in 3,000 Newborn Infants in Mexico

PEDIATRICS ◽  
1968 ◽  
Vol 41 (3) ◽  
pp. 664-666
Author(s):  
Héctor Márquez-Monter ◽  
Alessandra Carnevale-López ◽  
Susana Kofman-Alfaro
Keyword(s):  
General Hospital ◽  
Mexico City ◽  
Maternal Age ◽  
Congenital Abnormalities ◽  
Newborn Infants ◽  
Female Group ◽  
Male Group ◽  
Group 4 ◽  
Sex Chromatin ◽  
Group 3

A survey of sex chromatin was carried out in 3,000 newborn children at the General Hospital of Mexico City; 1,484 were males and 1,516 were females. In the male group 4 infants (0.26%) had positive chromatin and were considered to have a possible XXY or XXYY constitution. In the female group 3 infants (0.19%) did not show sex chromatin and were possible carriers of an XO complement. No correlation was found between the maternal age and number of pregnancies and the discrepant children. A comparison was made between the results obtained in this study and similar studies carried out in other countries. Fourteen instances of congenital abnormalities were found in this study; Down's syndrome was the most frequent (1/750-0.13%).

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