A new endocrine cell type of the human pancreatic islets

1972 ◽  
Vol 28 (8) ◽  
pp. 966-967 ◽  
Author(s):  
K. Jirásek ◽  
L. Kubeś
Keyword(s):  
Pancreatic Islets ◽  
Endocrine Cell ◽  
Cell Type ◽  
Human Pancreatic Islets ◽  
Endocrine Cell Type

scholarly journals Ghrelin, a Novel Growth Hormone-Releasing Acylated Peptide, Is Synthesized in a Distinct Endocrine Cell Type in the Gastrointestinal Tracts of Rats and Humans1

Endocrinology ◽  
2000 ◽  
Vol 141 (11) ◽  
pp. 4255-4261 ◽  
Author(s):  
Yukari Date ◽  
Masayasu Kojima ◽  
Hiroshi Hosoda ◽  
Akira Sawaguchi ◽  
Muhtashan S. Mondal ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Endocrine Cell ◽  
Cell Type ◽  
Endocrine Cell Type ◽  
Acylated Peptide

A peptide resembling COOH-terminal tetrapeptide amide of gastrin from a new gastrointestinal endocrine cell type

Nature ◽  
1979 ◽  
Vol 277 (5697) ◽  
pp. 575-578 ◽  
Author(s):  
LARS-INGE LARSSON ◽  
JENS F. REHFELD
Keyword(s):  
Endocrine Cell ◽  
Cell Type ◽  
Endocrine Cell Type

Localization of APP, a postulated new hormone, to a pancreatic endocrine cell type

1974 ◽  
Vol 42 (4) ◽  
pp. 377-382 ◽  
Author(s):  
L. -I. Larsson ◽  
F. Sundler ◽  
R. H�kanson ◽  
H. G. Pollock ◽  
J. R. Kimmel
Keyword(s):  
Endocrine Cell ◽  
Cell Type ◽  
Pancreatic Endocrine Cell ◽  
Endocrine Cell Type

scholarly journals Gene Signature of the Human Pancreatic ε Cell

Endocrinology ◽  
2018 ◽  
Vol 159 (12) ◽  
pp. 4023-4032 ◽  
Author(s):  
Giselle Dominguez Gutierrez ◽  
Jinrang Kim ◽  
Ann-Hwee Lee ◽  
Jenny Tong ◽  
JingJing Niu ◽  
...  
Keyword(s):  
Endocrine Cell ◽  
Metabolic Pathways ◽  
Cell Types ◽  
Gene Signature ◽  
Human Islet ◽  
Cell Type ◽  
Sequencing Technology ◽  
Surface Receptors ◽  
Molecular Features ◽  
Endocrine Cell Type

Abstract The ghrelin-producing ε cell represents the fifth endocrine cell type in human pancreatic islets. The abundance of ε cells in adult pancreas is extremely low, which has hampered the investigation on the molecular pathways regulating the development and the function of this cell type. In this study, we explored the molecular features defining the function of pancreatic ε cells isolated from adult nondiabetic donors using single-cell RNA sequencing technology. We focus on transcription factors, cell surface receptors, and genes involved in metabolic pathways that contribute to regulation of cellular function. Furthermore, the genes that separate ε cells from the other islet endocrine cell types are presented. This study expands prior knowledge about the genes important for ε cell functioning during development and provides a resource to interrogate the transcriptome of this rare human islet cell type.

scholarly journals Endocrine cell type sorting and mature architecture in the islets of Langerhans require expression of Roundabout receptors in β cells

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Melissa T. Adams ◽  
Jennifer M. Gilbert ◽  
Jesus Hinojosa Paiz ◽  
Faith M. Bowman ◽  
Barak Blum
Keyword(s):  
Islets Of Langerhans ◽  
Endocrine Cell ◽  
Cell Type ◽  
Β Cells ◽  
Endocrine Cell Type ◽  
Roundabout Receptors

scholarly journals RECURRENT GASTRIC CARCINOMA (ENDOCRINE CELL TYPE) SUCCESSFULLY TREATED WITH COMBINATION CHEMOTHERAPY-A CASE REPORT-

2000 ◽  
Vol 61 (6) ◽  
pp. 1469-1473 ◽  
Author(s):  
Nobuo UESHIGE ◽  
Hideto NAKAGAWA ◽  
Juniti SUGAYA ◽  
Fujio TOMITA ◽  
Takeo KOSAKA ◽  
...  
Keyword(s):  
Case Report ◽  
Gastric Carcinoma ◽  
Combination Chemotherapy ◽  
Endocrine Cell ◽  
Cell Type ◽  
Endocrine Cell Type
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