Effects of progesterone and estradiol benzoate on superoxide dismutase activity in the brain of male rats

1996 ◽  
Vol 52 (3) ◽  
pp. 221-224 ◽  
Author(s):  
S. Pajović ◽  
Z. S. Saičić ◽  
M. B. Spasić ◽  
V. M. Petrović ◽  
J. V. Martinović
Keyword(s):  
Superoxide Dismutase ◽  
Estradiol Benzoate ◽  
Superoxide Dismutase Activity ◽  
Male Rats ◽  
The Brain

Effects of estradiol benzoate and progesterone on superoxide dismutase activity in the rat liver

1997 ◽  
Vol 20 (4) ◽  
pp. 203-206 ◽  
Author(s):  
J. Kasapović ◽  
S. B. Pajović ◽  
D. T. Kanazir ◽  
J. V. Martinović
Keyword(s):  
Superoxide Dismutase ◽  
Rat Liver ◽  
Estradiol Benzoate ◽  
Superoxide Dismutase Activity

Superoxide dismutase activity in the brain of rats prenatally treated with lead

1999 ◽  
Vol 128 (6) ◽  
pp. 1239-1240
Author(s):  
M. G. Uzbekov ◽  
I. K. Karpachevskaya ◽  
N. I. Bubnova ◽  
G. V. Kulikova
Keyword(s):  
Superoxide Dismutase ◽  
Superoxide Dismutase Activity ◽  
The Brain

scholarly journals Comparing the effect of 6 weeks of continuous and interval aerobic training on vascular endothelial growth factor and superoxide dismutase enzyme in hippocampus of male rats of Parkinson's model

2019 ◽  
Author(s):  
Saeid Moradi ◽  
Abdolhamid Habibi ◽  
Mohammad Reza Tabande ◽  
Saeid Shakerian
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Superoxide Dismutase ◽  
Growth Factor ◽  
Aerobic Exercise ◽  
Male Rats ◽  
Average Weight ◽  
Vascular Endothelial ◽  
Significant Difference ◽  
Endothelial Growth Factor ◽  
The Brain

Introdution: Based on researches, increased levels of vascular endothelial growth factor and antioxidant parameters in areas of the brain that are more affected by Parkinson's disease have a potential therapeutic effect. Therefore, the purpose of this study was to compare the effect of 6 weeks continuous and interval aerobic exercises on vascular endothelial growth factor and superoxide dismutase enzyme; Parkinson's rats. Methods: In this experimental study, 24 male Wistar male rats (12 weeks) with an average weight of 250 to 350 grams were used. Subjects were treated with reserpine to Parkinson's, then divided into 6 groups. Aerobic exercises were performed for 6 weeks. After 48 hours of the last training session, the rats were killed, then the tissue of the hippocampus was separated from other parts of the brain, and vascular endothelial growth factor and superoxide dismutase enzyme were measured using specific kits. The results were analyzed using one way analysis of variance analysis and Bonferroni post hoc test. Results: The results of this study showed that 6 weeks of continuous and interval aerobic exercise increased vascular endothelial growth factor levels in Parkinson's rats (p = 0.01). There was no significant difference between the two groups of interval exercises compared to the continuous training group (p = 0.87). Also, these exercises did not significantly affect the superoxide dismutase enzymes (p = 0.47). Conclusion: Based on the findings of this study, it has been shown that 6 weeks of continuous and periodic aerobic exercise increases the vascular endothelial growth factor, but these exercises  have not significantly changed the superoxide dismutase enzyme. Introdution: Based on researches, increased levels of vascular endothelial growth factor and antioxidant parameters in areas of the brain that are more affected by Parkinson's disease have a potential therapeutic effect. Therefore, the purpose of this study was to compare the effect of 6 weeks continuous and interval aerobic exercises on vascular endothelial growth factor and superoxide dismutase enzyme; Parkinson's rats. Methods: In this experimental study, 24 male Wistar male rats (12 weeks) with an average weight of 250 to 350 grams were used. Subjects were treated with reserpine to Parkinson's, then divided into 6 groups. Aerobic exercises were performed for 6 weeks. After 48 hours of the last training session, the rats were killed, then the tissue of the hippocampus was separated from other parts of the brain, and vascular endothelial growth factor and superoxide dismutase enzyme were measured using specific kits. The results were analyzed using one way analysis of variance analysis and Bonferroni post hoc test. Results: The results of this study showed that 6 weeks of continuous and interval aerobic exercise increased vascular endothelial growth factor levels in Parkinson's rats (p = 0.01). There was no significant difference between the two groups of interval exercises compared to the continuous training group (p = 0.87). Also, these exercises did not significantly affect the superoxide dismutase enzymes (p = 0.47). Conclusion: Based on the findings of this study, it has been shown that 6 weeks of continuous and periodic aerobic exercise increases the vascular endothelial growth factor, but these exercises  have not significantly changed the superoxide dismutase enzyme.

Effects of Lu-Duo-Wei Capsules on Superoxide Dismutase Activity and Contents of Malondialdehyde and Lipofuscin in the Brain of the Housefly

2000 ◽  
Vol 28 (02) ◽  
pp. 259-262 ◽  
Author(s):  
Xu Cui ◽  
Xiang-Guo Dai ◽  
Wen-Bin Li ◽  
Bing-Lie Zhang ◽  
Yun-Zhong Fang
Keyword(s):  
Superoxide Dismutase ◽  
Free Radical ◽  
Synergistic Effect ◽  
Musca Domestica ◽  
Experimental Period ◽  
Superoxide Dismutase Activity ◽  
Tea Polyphenol ◽  
Lipofuscin Accumulation ◽  
The Brain

The biochemical actions of Lu-Duo-Wei capsules and tea polyphenol in relation to their antioxidant capability have been compared in the male housefly, Musca domestica. It was found that tea polyphenol had the effect of increasing the activity of superoxide dismutase (SOD) in the brain of the housefly only at the 60th day in the experimental period whereas Lu-Duo-Wei showed more obvious effects on SOD than tea polyphenol irrespective of experimental days. Moreover, the contents of malondialdehyde (MDA) and the rate of lipofuscin accumulation were decreased by the effect of Lu-Duo-Wei at the 20th, 40th, 50th and 60th days, while the similar effect of tea polyphenol on the content of MDA and lipofuscin was observed only at the 40th day. These results indicated that the biochemical actions of Lu-Duo-Wei in antiaging was much stronger than those of tea polyphenol, the mechanism of which was probably related to the synergistic effect of its involved antioxidants and others as well as the exclusive promotion of SOD biosynthesis/or a reduction of free radical-induced damage of the enzyme.

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