The physiological effects of ionic lanthanum on the insect blood-brain barrier

1976 ◽  
Vol 32 (6) ◽  
pp. 720-721 ◽  
Author(s):  
M. V. Thomas ◽  
R. A. Leslie
Keyword(s):  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Physiological Effects ◽  
Blood Brain ◽  
Ionic Lanthanum

Experimental Disruption of the Blood-Brain Barrier System in an Insect (Periplaneta Americana)

1973 ◽  
Vol 59 (3) ◽  
pp. 711-724
Author(s):  
J. E. TREHERNE
Keyword(s):  
Blood Brain Barrier ◽  
Periplaneta Americana ◽  
Brain Barrier ◽  
Ultrastructural Changes ◽  
Hypertonic Solution ◽  
Electron Microscopic ◽  
Blood Brain ◽  
Ionic Lanthanum ◽  
Electrophysiological Studies ◽  
Microscopic Studies

1. The effects of hypertonic urea and hypertonic glucose solutions upon the ‘blood-brain barrier’ in the isolated abdominal nerve cord of the cockroach have been studied. 2. Electrophysiological studies showed that a hypertonic solution of urea, but not of glucose, was effective in reducing the barrier to the entry of potassium and the loss of sodium. 3. Electron-microscopic studies revealed no significant ultrastructural changes, and no disruption of the perineurial barrier to the entry of ionic lanthanum, following comparable exposure to the hypertonic solutions. 4. It is suggested that this alteration of the blood-brain barrier may result from a selective change in permeability of the perineurial membranes or tight junctions.

Conformationally Constrained Peptide Drugs Targeted at the Blood-Brain Barrier

1995 ◽  
Author(s):  
Thomas P. Davis ◽  
Thomas J. Abbruscato ◽  
Elizabeth Brownson ◽  
Victor J. Hruby
Keyword(s):  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Peptide Drugs ◽  
Conformationally Constrained ◽  
Blood Brain
Sign in / Sign up

Export Citation Format

Share Document