Significance of right ventricular filling for left ventricular enddiastolic pressure-volume relationship under acute hypoxia in the dog

1987 ◽  
Vol 82 (2) ◽  
pp. 109-122 ◽  
Author(s):  
Ch. Brilla ◽  
G. Kissling ◽  
R. Jacob
Keyword(s):  
Right Ventricular ◽  
Acute Hypoxia ◽  
Left Ventricular ◽  
Volume Relationship ◽  
Right Ventricular Filling ◽  
Pressure Volume Relationship ◽  
Ventricular Filling ◽  
Enddiastolic Pressure

scholarly journals Influence of Right Ventricular Filling Pressure on Left Ventricular Pressure and Dimension

1974 ◽  
Vol 34 (4) ◽  
pp. 498-504 ◽  
Author(s):  
CHARLES E. BEMIS ◽  
JUAN R. SERUR ◽  
DAVID BORKENHAGEN ◽  
EDMUND H. SONNENBLICK ◽  
CHARLES W. URSCHEL
Keyword(s):  
Right Ventricular ◽  
Left Ventricular Pressure ◽  
Left Ventricular ◽  
Filling Pressure ◽  
Ventricular Pressure ◽  
Ventricular Filling Pressure ◽  
Right Ventricular Filling ◽  
Ventricular Filling

Cardiovascular effects of positive-pressure ventilation in normal subjects

1979 ◽  
Vol 47 (2) ◽  
pp. 453-461 ◽  
Author(s):  
S. S. Cassidy ◽  
W. L. Eschenbacher ◽  
C. H. Robertson ◽  
J. V. Nixon ◽  
G. Blomqvist ◽  
...  
Keyword(s):  
Heart Rate ◽  
Cardiac Output ◽  
Right Ventricular ◽  
Positive Pressure Ventilation ◽  
Normal Subjects ◽  
Left Ventricular ◽  
Right Atrial ◽  
Positive Pressure ◽  
Right Ventricular Filling ◽  
Ventricular Filling

In normal subjects during 15-min positive-pressure ventilation with 10 cmH2O end-expiratory pressure (PEEP), cardiac output fell 19% due to a fall in stroke volume. Transmural mean right atrial pressure rose 3.1 cmH2O and right ventricular end-diastolic diameter increased 15%. Simultaneously, left ventricular end-diastolic diameter decreased 21%, ejection time increased 11%, and velocity of circumferential fiber shortening fell 30%. Thus, right ventricular filling increased and left ventricular filling decreased. The function of the right ventricle was impaired and the function of the left ventricle may have been impaired. Cardiac output gradually increased due to a 7% increase in heart rate as PEEP was continued for 1 h and transmural mean right atrial pressure also increased further by 2.4 cmH2O. Compensation for the reduced stroke volume occurred as filling pressures and heart rate rose, but ventricular function remained impaired for the entire duration of PEEP. On resuming spontaneous breathing, cardiac output and ventricular function returned to base-line levels. We conclude that the reduced cardiac output during PEEP is not due to a direct mechanical reduction in right ventricular filling.

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