Fine structural alterations of presynaptic endings in the superior cervical ganglion of the cat after exhausting preganglionic stimulation

1970 ◽  
Vol 26 (6) ◽  
pp. 629-630 ◽  
Author(s):  
á. Párducz ◽  
O. Fehér
Keyword(s):  
Superior Cervical Ganglion ◽  
Structural Alterations ◽  
Cervical Ganglion ◽  
Preganglionic Stimulation

The Effect of Hemicholinium-3 on Choline and Acetylcholine Levels in a Sympathetic Ganglion

1975 ◽  
Vol 53 (3) ◽  
pp. 451-457 ◽  
Author(s):  
J. C. Khatter ◽  
A. J. D. Friesen
Keyword(s):  
Superior Cervical Ganglion ◽  
Sympathetic Ganglion ◽  
Transport Systems ◽  
Cholinergic Nerves ◽  
Choline Transport ◽  
Site Of Action ◽  
Cervical Ganglion ◽  
Preganglionic Stimulation ◽  
Rate Of Decline ◽  
Stimulation Of

Preganglionic stimulation of the cat's superior cervical ganglion in the presence of hemicholinium-3 (HC-3) produced the expected depletion of acetylcholine (ACh) stores, but failed to cause a corresponding reduction in the choline content. These results suggest that either HC-3 possesses an intracellular site of action or that in lower doses it selectively inhibits a specialized choline transport system in cholinergic nerves. At a dose of 2 mg/kg, HC-3 probably blocked ACh synthesis completely in ganglia stimulated at 20 Hz. Under these conditions, there was a rapid depletion of ACh to about 50% of control levels during the first 5 min of stimulation and thereafter the rate of decline in ACh levels proceeded at a much slower pace. Since the 2 mg/kg dose of HC-3 did not raise plasma choline concentrations, it may be assumed that non-specialized choline transport systems in other tissues were not significantly inhibited by this dose of HC-3. However, when the dose of HC-3 was increased to 4 mg/kg, plasma choline levels increased by 58%.

Late Discharges in Dog's Sympathetic Ganglia

1972 ◽  
Vol 50 (3) ◽  
pp. 263-269 ◽  
Author(s):  
S. S. Chen
Keyword(s):  
Superior Cervical Ganglion ◽  
Stimulus Frequency ◽  
Sympathetic Ganglia ◽  
Late Response ◽  
Before And After ◽  
Cervical Ganglion ◽  
High Stimulus ◽  
Time Courses ◽  
Preganglionic Stimulation ◽  
Muscarinic And Nicotinic Receptors

In the dog a preganglionic stimulation at a high stimulus frequency for 10–15 s elicited a two-wave response, early and late responses in the perfused ear (vasoconstriction), as well as early and late contractions in the nictitating membrane. Both the late contraction and the late response could be aborted by cooling the superior cervical ganglion, and restored by rewarming the ganglion. Both were resistant to atropine and hexamethonium combined. Their magnitude depended upon the duration of stimulation and upon the stimulus frequency used. Their time courses were similar both before and after hexamethonium or chilling. Therefore, it is concluded that they are manifestations of late discharges in the superior cervical ganglion, which are independent of both muscarinic and nicotinic receptors in the ganglion. A similar but less prominent phenomenon was demonstrated in the lumbosacral sympathetic ganglion of the dog by studying the responses of the retractor penis muscle and the perfused hind limb to preganglionic stimulation.

scholarly journals The effect of preganglionic stimulation on the incorporation of l-[U-14C]valine into the protein of the superior cervical ganglion of the guinea pig

1970 ◽  
Vol 118 (5) ◽  
pp. 813-818 ◽  
Author(s):  
P. Banks
Keyword(s):  
Guinea Pig ◽  
Superior Cervical Ganglion ◽  
Superior Cervical Ganglia ◽  
Cervical Ganglion ◽  
Cervical Ganglia ◽  
Preganglionic Stimulation ◽  
Energy Dependent ◽  
Stimulation Of

1. Superior cervical ganglia from the guinea pig carry out an energy-dependent incorporation of l-[14C]valine into protein in vitro. 2. Stimulation of the preganglionic nerve at a physiological frequency for more than a few minutes decreases the ability of the ganglia to incorporate labelled valine into protein.

Evidence for a Blood Ganglion Barrier in the Superior Cervical Ganglion of the Rat

1982 ◽  
Vol 40 ◽  
pp. 204-204
Author(s):  
D. M. DePace
Keyword(s):  
Blood Vessels ◽  
Superior Cervical Ganglion ◽  
Peripheral Nerves ◽  
Time Schedule ◽  
Transmission Electron ◽  
Cervical Ganglion ◽  
The Central Nervous System ◽  
Cervical Ganglia ◽  
Capillary Circulation ◽  
And Control

The majority of blood vessels in the superior cervical ganglion possess a continuous endothelium with tight junctions. These same features have been associated with the blood brain barrier of the central nervous system and peripheral nerves. These vessels may perform a barrier function between the capillary circulation and the superior cervical ganglion. The permeability of the blood vessels in the superior cervical ganglion of the rat was tested by intravenous injection of horseradish peroxidase (HRP). Three experimental groups of four animals each were given intravenous HRP (Sigma Type II) in a dosage of.08 to.15 mg/gm body weight in.5 ml of.85% saline. The animals were sacrificed at five, ten or 15 minutes following administration of the tracer. Superior cervical ganglia were quickly removed and fixed by immersion in 2.5% glutaraldehyde in Sorenson's.1M phosphate buffer, pH 7.4. Three control animals received,5ml of saline without HRP. These were sacrificed on the same time schedule. Tissues from experimental and control animals were reacted for peroxidase activity and then processed for routine transmission electron microscopy.

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