Bone mineral density in patients with cervical and trochanteric fractures of the proximal femur

1991 ◽  
Vol 1 (2) ◽  
pp. 81-86 ◽  
Author(s):  
E. Vega ◽  
C. Mautalen ◽  
H. Gómez ◽  
A. Garrido ◽  
L. Melo ◽  
...  
Orthopedics ◽  
2004 ◽  
Vol 27 (12) ◽  
pp. 1266-1271 ◽  
Author(s):  
Harlan C Amstutz ◽  
Edward Ebramzadeh ◽  
Akos Sarkany ◽  
Michel Le Duff ◽  
Robert Rude

2020 ◽  
Vol 13 (2) ◽  
pp. 153-161
Author(s):  
Lejla Milisic ◽  
Sandra Vegar-Zubovic ◽  
Amina Valjevac ◽  
Suada Hasanovic-Vučković

Objectives: Although Dual-energy X-ray Absorptiometry (DXA) is gold standard for osteoporosis diagnosis, several reports have shown discordant T-score values measured by Quantitative Computed Tomography (QCT) and DXA especially in obese subjects, but it is still not clear whether BMD measurement by two modalities is affected by overall obesity or central obesity in postmenopausal females. Therefore, the aims of this study were to compare BMD and T-scores by DXA and QCT and to evaluate whether these two osteoporosis assessment modalities yield different T-score values in postmenopausal females with obesity and central obesity. Methods: This cross-sectional study enrolled 44 postmenopausal females, referred for osteoporosis screening. Anthropometric indices (BMI-body mass index, WC-waist circumference and ICOindex of central obesity) were measured and females underwent an assessment of bone mineral density by DXA and QCT. Results: Lumbar Spine (LS) T-score values were observed to be significantly lower by DXA compared to qCT in females with BMI >25 kg/m2, (-1.9±1.5 vs. -2.3±1.2; p=0.039), in females with WC>88 cm(-1.9±1.5 vs. -2.4±1.2; p=0.008) and in females with ICO>0.5(-1.96±1.4 vs. -2.5±1.2; p=0.004). However, in normal-weight females and in those without central obesity, LS T-scores by DXA were not different than qCT. DXA at lumbar spine and proximal femur revealed osteoporosis in 47.7% and 11.4% respectively, while QCT detected osteoporosis in 61.4% of females (p<0.001). Measures of central obesity; ICO and WC were not associated with QCT bone mineral density (BMD) (r=0.14 and r=0.21, respectively), but were positively associated with both DXALS BMD (r=0.29 and r=0.31; p<0.05) and DXA proximal femur BMD (r=0.41 and r=0.44; p<0.01). Conclusion: Our results suggest that obesity is associated with lower T-scores by DXA compared to QCT. Caution is needed when assessing osteoporosis status in obese postmenopausal females. However, further studies with larger sample size are needed to confirm the findings.


Radiology ◽  
2018 ◽  
Vol 287 (2) ◽  
pp. 608-619 ◽  
Author(s):  
Gregory Chang ◽  
Chamith S. Rajapakse ◽  
Cheng Chen ◽  
Arakua Welbeck ◽  
Kenneth Egol ◽  
...  

1999 ◽  
Vol 64 (3) ◽  
pp. 257-258 ◽  
Author(s):  
Emm. K. Dretakis ◽  
E. Papakitsou ◽  
G. M. Kontakis ◽  
K. Dretakis ◽  
S. Psarakis ◽  
...  

2004 ◽  
Vol 259 (2) ◽  
pp. 361-364 ◽  
Author(s):  
S. Akin ◽  
S. Isikli ◽  
F. Korkusuz ◽  
M. Ungan ◽  
A. Senkoylu

2013 ◽  
Vol 5 (2) ◽  
pp. 16 ◽  
Author(s):  
Stefan Grote ◽  
Tatjana Noeldeke ◽  
Michael Blauth ◽  
Wolf Mutschler ◽  
Dominik Bürklein

Knowledge of local bone quality is essential for surgeons to determine operation techniques. A device for intraoperative measurement of local bone quality has been developed by the AO-Research Foundation (DensiProbe®). We used this device to experimentally measure peak breakaway torque of trabecular bone in the proximal femur and correlated this with local bone mineral density (BMD) and failure load. Bone mineral density of 160 cadaver femurs was measured by <em>ex situ </em>dual-energy X-ray absorptiometry. The failure load of all femurs was analyzed by side-impact analysis. Femur fractures were fixed and mechanical peak torque was measured with the DensiProbe® device. Correlation was calculated whereas correlation coefficient and significance was calculated by Fisher’s Z-transformation. Moreover, linear regression analysis was carried out. The unpaired Student’s t-test was used to assess the significance of differences. The Ward triangle region had the lowest BMD with 0.511 g/cm2 (±0.17 g/cm2), followed by the upper neck region with 0.546 g/cm2 (±0.16 g/cm2), trochanteric region with 0.685 g/cm2 (±0.19 g/cm2) and the femoral neck with 0.813 g/cm2 (±0.2 g/cm2). Peak torque of DensiProbe® in the femoral head was 3.48 Nm (±2.34 Nm). Load to failure was 4050.2 N (±1586.7 N). The highest correlation of peak torque measured by Densi Probe® and load to failure was found in the femoral neck (r=0.64, P&lt;0.001). The overall correlation of mechanical peak torque with T-score was r=0.60 (P&lt;0.001). A correlation was found between mechanical peak torque, load to failure of bone and BMD <em>in vitro</em>. Trabecular strength of bone and bone mineral density are different aspects of bone strength, but a correlation was found between them. Mechanical peak torque as measured may contribute additional information about bone strength, especially in the perioperative testing.


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