Increased regional cerebral glucose metabolism and semantic memory performance in Alzheimer's disease: A pilot double blind transdermal nicotine positron emission tomography study

1996 ◽  
Vol 6 (2) ◽  
pp. 61-79 ◽  
Author(s):  
Randolph W. Parks ◽  
Robert E. Becker ◽  
Robert F. Rippey ◽  
David G. Gilbert ◽  
Jane R. Matthews ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Glucose Metabolism ◽  
Semantic Memory ◽  
Memory Performance ◽  
Emission Tomography ◽  
Positron Emission Tomography Study ◽  
Double Blind ◽  
Positron Emission ◽  
Transdermal Nicotine ◽  
Regional Cerebral Glucose Metabolism

Altered Regional Cerebral Glucose Metabolism in Internet Game Overusers: A 18F-fluorodeoxyglucose Positron Emission Tomography Study

CNS Spectrums ◽  
2010 ◽  
Vol 15 (3) ◽  
pp. 159-166 ◽  
Author(s):  
Hyun Soo Park ◽  
Sang Hee Kim ◽  
Seong Ae Bang ◽  
Eun Jin Yoon ◽  
Sang Soo Cho ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Glucose Metabolism ◽  
Impulse Control ◽  
Reward Processing ◽  
Emission Tomography ◽  
Positron Emission Tomography Study ◽  
Fluorodeoxyglucose Positron Emission Tomography ◽  
Positron Emission ◽  
Regional Cerebral Glucose Metabolism ◽  
Fluorodeoxyglucose Positron Emission

ABSTRACTIntroduction: Internet game overuse is an emerging disorder and features diminished impulse control and poor reward-processing. In an attempt to understand the neurobiological bases of Internet game overuse, we investigated the differences in regional cerebral glucose metabolism at resting state between young individuals with Internet game overuse and those with normal use using 18F-fluorodeoxyglucose positron emission tomography study.Methods: Twenty right-handed male participants (9 normal users: 24.7±2.4 years of age, 11 overusers: 23.5±2.9 years of age) participated. A trait measure of impulsivity was also completed after scanning.Results: Internet game overusers showed greater impulsiveness than the normal users and there was a positive correlation between the severity of Internet game overuse and impulsiveness. Imaging data showed that the overusers had increased glucose metabolism in the right middle orbitofrontal gyrus, left caudate nucleus, and right insula, and decreased metabolism in the bilateral postcentral gyrus, left precentrai gyrus, and bilateral occipital regions compared to normal users.Conclusion: Internet game overuse may be associated with abnormal neurobiological mechanisms in the orbitofrontal cortex, striatum, and sensory regions, which are implicated in impulse control, reward processing, and somatic representation of previous experiences. Our results support the idea that Internet game overuse shares psychological and neural mechanisms with other types of impulse control disorders and substance/non-substance-related addiction.

scholarly journals Memory Performance and the Growth Hormone/Insulin-Like Growth Factor Axis in Elderly: A Positron Emission Tomography Study

2005 ◽  
Vol 81 (1) ◽  
pp. 31-40 ◽  
Author(s):  
Lucia I. Arwert ◽  
Dick J. Veltman ◽  
Jan Berend Deijen ◽  
Adriaan A. Lammertsma ◽  
Cees Jonker ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Growth Hormone ◽  
Growth Factor ◽  
Memory Performance ◽  
Emission Tomography ◽  
Positron Emission Tomography Study ◽  
Insulin Like Growth Factor ◽  
Positron Emission
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