Mechanism of inactivation of single sodium channels after modification by chloramine-T, sea anemone toxin and scorpion toxin

1988 ◽  
Vol 106 (1) ◽  
pp. 29-40 ◽  
Author(s):  
Karoly Nagy
Keyword(s):  
Sodium Channels ◽  
Sea Anemone ◽  
Scorpion Toxin ◽  
Sea Anemone Toxin ◽  
Chloramine T ◽  
Single Sodium Channels

The specificity of Av3 sea anemone toxin for arthropods is determined at linker DI/SS2–S6 in the pore module of target sodium channels

2014 ◽  
Vol 463 (2) ◽  
pp. 271-277 ◽  
Author(s):  
Maya Gur Barzilai ◽  
Roy Kahn ◽  
Noa Regev ◽  
Dalia Gordon ◽  
Yehu Moran ◽  
...  
Keyword(s):  
Sodium Channel ◽  
Sodium Channels ◽  
Receptor Site ◽  
Sea Anemone ◽  
Sea Anemone Toxin

A sodium channel determinant that dictates the specificity of Av3 sea anemone toxin for arthropods was identified using channel-swapping experiments and mutagenesis. This finding provides a clue as to the receptor site of Av3 on the sodium channel.

Expression and Mutagenesis of the Sea Anemone Toxin Av2 Reveals Key Amino Acid Residues Important for Activity on Voltage-Gated Sodium Channels†

Biochemistry ◽  
2006 ◽  
Vol 45 (29) ◽  
pp. 8864-8873 ◽  
Author(s):  
Yehu Moran ◽  
Lior Cohen ◽  
Roy Kahn ◽  
Izhar Karbat ◽  
Dalia Gordon ◽  
...  
Keyword(s):  
Amino Acid ◽  
Sodium Channels ◽  
Sea Anemone ◽  
Amino Acid Residues ◽  
Voltage Gated ◽  
Voltage Gated Sodium Channels ◽  
Sea Anemone Toxin

New Sea Anemone Toxin RTX-VI Selectively Modulates Voltage-Gated Sodium Channels

2020 ◽  
Vol 495 (1) ◽  
pp. 292-295
Author(s):  
R. S. Kalina ◽  
S. Peigneur ◽  
I. N. Gladkikh ◽  
P. S. Dmitrenok ◽  
N. Y. Kim ◽  
...  
Keyword(s):  
Sodium Channels ◽  
Sea Anemone ◽  
Voltage Gated ◽  
Voltage Gated Sodium Channels ◽  
Sea Anemone Toxin
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