Effect of vasoactive intestinal polypeptide (VIP) on glucose and lipid metabolism of isolated rat adipocytes

1988 ◽  
Vol 188 (3) ◽  
pp. 189-195 ◽  
Author(s):  
H. Hauner ◽  
G. Glatting ◽  
D. Kaminska ◽  
E. F. Pfeiffer
2002 ◽  
Vol 26 (7) ◽  
pp. 912-919 ◽  
Author(s):  
MJ Moreno-Aliaga ◽  
JA Martínez ◽  
KL Stanhope ◽  
MP Fernández-Otero ◽  
PJ Havel

2009 ◽  
Vol 91 (03) ◽  
pp. 350-354 ◽  
Author(s):  
H. Hauner ◽  
G. Glatting ◽  
H. H. Ditschuneit ◽  
E. F. Pfeiffer

Reproduction ◽  
1990 ◽  
Vol 90 (2) ◽  
pp. 465-472 ◽  
Author(s):  
G. Schmidt ◽  
J. Jorgensen ◽  
P. Kannisto ◽  
F. Liedberg ◽  
B. Ottesen ◽  
...  

1987 ◽  
Vol 15 (01n02) ◽  
pp. 31-42 ◽  
Author(s):  
T.B. Ng ◽  
C.M. Wong ◽  
W.W. Li ◽  
H.W. Yeung

Fruits and seeds of the bitter gourd Momordica charantia (Family Cucurbitaceae) were extracted with the acidic ethanol. The extract was adjusted to pH 3 and proteins and peptides were precipitated by additon of a copious volume of aceton. The precipitate was dissolved, dialyzed and lyophilized. The resulting material, designated "p-fraction" was tested for antilipolytic and lipogenic activities. Seed "p-fraction" was further chromatographed on fetuin agraose to yield an unadsorbed fraction (F) which could be fractioned by gel filtration on Sephadex G-10 to give an unretarted fraction (F1) and a retarted function (F2). Fruit "p-fraction" exhibited antilipolytic activity in hamster adipocytes and stimulated 3H-glucose incorporation into lipids, F1, a saponin containing fraction, inhibited both lipolysis and 3H-glucose incorporation into lipids. F2 enhance 3H-glucose corporation into lipid. The results are indicavie of the presence of compounds with insulinomimetic activities in M. charantia fruits and seeds.


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