Mechanism of increased tracheo-bronchial response to inhalative acetylcholine aerosol in pulmonary vascular congestion and unilateral pulmonary artery occlusion

1977 ◽  
Vol 170 (3) ◽  
pp. 229-239 ◽  
Author(s):  
M. S. Islam ◽  
W. T. Ulmer
Keyword(s):  
Pulmonary Artery ◽  
Artery Occlusion ◽  
Vascular Congestion ◽  
Unilateral Pulmonary Artery Occlusion

UNILATERAL PULMONARY ARTERY OCCLUSION IN MAN

1957 ◽  
Vol 34 (2) ◽  
pp. 206-227 ◽  
Author(s):  
Bernard L. Brofman ◽  
Bernard L. Charms ◽  
Paul M. Kohn ◽  
John Elder ◽  
Robert Newman ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Artery Occlusion ◽  
Unilateral Pulmonary Artery Occlusion

Microvascular injury distal to unilateral pulmonary artery occlusion

1981 ◽  
Vol 51 (4) ◽  
pp. 845-851 ◽  
Author(s):  
R. L. Johnson ◽  
S. S. Cassidy ◽  
M. Haynes ◽  
R. L. Reynolds ◽  
W. Schulz
Keyword(s):  
Pulmonary Artery ◽  
Left Lung ◽  
Left Pulmonary Artery ◽  
Artery Occlusion ◽  
Diffusing Capacity ◽  
Pulmonary Capillary Blood Flow ◽  
Pulmonary Capillary ◽  
Pulmonary Capillary Blood ◽  
Rebreathing Method ◽  
Unilateral Pulmonary Artery Occlusion

We explored three questions: 1) does edema fluid accumulate distal to temporary unilateral pulmonary artery occlusion (TUPAO); 2) if so how rapidly does it accumulate; and 3) how is it affected by positive end-expiratory pressure (PEEP)? Using a tracheal divider we measured pulmonary capillary blood flow (Qc), tissue volume (Vt), and diffusing capacity (DLCO) in each lung with a rebreathing method. After control measurements in 12 dogs, the left pulmonary artery was occluded and measurements were repeated at intervals during 4 h of occlusion and 30 min after release of the occlusion. Six of the dogs were ventilated with 10 cmH2O PEEP. Finally the lungs were removed, weighed, and fixed for histology. TUPAO caused a 29% increase in Vt of the left lung without PEEP and a 59% increase with PEEP. After release of the occlusion, Qc and DLCO in the left lung returned to control levels within 30 min in dogs not on PEEP but remained depressed in dogs ventilated with PEEP even though PEEP was removed. At postmortem the left lung weighed more than expected in both groups of dogs but was significantly heavier in those on PEEP. Histology confirmed bronchovascular cuffing with edema and hemorrhage.

Temporary Unilateral Pulmonary Artery Occlusion: A Method for Controlling Swan-Ganz Catheter–Induced Hemoptysis

1984 ◽  
Vol 37 (6) ◽  
pp. 508-510 ◽  
Author(s):  
J. Gilbert Stone ◽  
Alber N. Faltas ◽  
Hoshang J. Khambatta ◽  
Allen I. Hyman ◽  
James R. Malm
Keyword(s):  
Pulmonary Artery ◽  
Artery Occlusion ◽  
Unilateral Pulmonary Artery Occlusion

scholarly journals Successful Infant Pneumonectomy with Unilateral Pulmonary Artery Occlusion Test

2018 ◽  
Vol 59 (1) ◽  
pp. 237-239 ◽  
Author(s):  
Koji Kato ◽  
Taichi Kato ◽  
Satoshi Hayano ◽  
Yoshie Fukasawa ◽  
Atsushi Numaguchi ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Artery Occlusion ◽  
Occlusion Test ◽  
Unilateral Pulmonary Artery Occlusion

Changes in regional lung mechanics and ventilation distribution after unilateral pulmonary artery occlusion

1997 ◽  
Vol 82 (3) ◽  
pp. 882-891 ◽  
Author(s):  
Brett A. Simon ◽  
Koichi Tsuzaki ◽  
Jose G. Venegas
Keyword(s):  
Pulmonary Artery ◽  
Tissue Level ◽  
Artery Occlusion ◽  
Lung Mechanics ◽  
Ventilation Distribution ◽  
Lung Capacity ◽  
Regional Lung ◽  
Before And After ◽  
Normalized Parameters ◽  
Unilateral Pulmonary Artery Occlusion

Simon, Brett A., Koichi Tsuzaki, and Jose G. Venegas.Changes in regional lung mechanics and ventilation distribution after unilateral pulmonary artery occlusion. J. Appl. Physiol. 82(3): 882–891, 1997.—Regional pneumoconstriction induced by alveolar hypocapnia is an important homeostatic mechanism for optimization of ventilation-perfusion matching. We used positron imaging of13NN-equilibrated lungs to measure the distribution of regional tidal volume (Vt), lung volume (Vl), and lung impedance ( Z) before and after left (L) pulmonary artery occlusion (PAO) in eight anesthetized, open-chest dogs. Measurements were made during eucapnic sinusoidal ventilation at 0.2 Hz with 4-cmH2O positive end expiratory pressure. Right (R) and L lung impedances ( Z rand Z l) were determined from carinal pressure and positron imaging of dynamic regional Vl. LPAO caused an increase in ‖ Z l‖ relative to ‖ Z r‖, resulting in a shift in Vt away from the PAO side, with a L/R ‖ Z‖ ratio changing from 1.20 ± 0.07 (mean ± SE) to 2.79 ± 0.85 after LPAO ( P < 0.05). Although mean L lung Vl decreased slightly, theVl normalized parameters specific admittance and specific compliance both significantly decreased with PAO. Lung recoil pressure at 50% total lung capacity also increased after PAO. We conclude that PAO results in an increase in regional lung Z that shifts ventilation away from the affected area at normal breathing frequencies and that this effect is not due to a change in Vl but reflects mechanical constriction at the tissue level.

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