Stimulation of growth hormone secretion with human growth hormone releasing factors (GRF1–44, GRF1–40, GRF1–29) in normal subjects

1984 ◽  
Vol 62 (23) ◽  
pp. 1140-1143 ◽  
Author(s):  
M. Losa ◽  
J. Schopohl ◽  
O. A. Müller ◽  
K. Werder
Keyword(s):  
Growth Hormone ◽  
Human Growth Hormone ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Human Growth ◽  
Normal Subjects ◽  
Releasing Factors ◽  
Stimulation Of

Dissociation between circulating concentrations of immunoreactive growth hormone releasing factor and growth hormone in normal human subjects

1987 ◽  
Vol 72 (2) ◽  
pp. 181-185 ◽  
Author(s):  
A. M. Sopwith ◽  
Elizabeth S. Penny ◽  
N. Lytras ◽  
G. M. Besser ◽  
Lesley H. Rees
Keyword(s):  
Growth Hormone ◽  
Human Growth Hormone ◽  
Human Subjects ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Human Growth ◽  
Normal Subjects ◽  
Peripheral Circulation ◽  
Growth Hormone Releasing Factor ◽  
Specific Radioimmunoassay

1. Using a highly specific radioimmunoassay we have measured immunoreactive human growth hormone releasing factor (ir-hGRF) concentrations in the peripheral circulation of a total of 12 normal subjects. 2. Neither insulin-induced hypoglycaemia, intravenous arginine nor oral carbohydrate caused any change in venous plasma ir-hGRF concentrations, despite the expected stimulation and suppression respectively of growth hormone secretion. 3. Growth hormone secretion was not increased by oral fat or protein but each of these two foods stimulated ir-hGRF concentrations two- to fourfold. 4. Spontaneous pulses of growth hormone secretion on control days were unaccompanied by any increase in plasma ir-hGRF. 5. The dissociation between peripheral circulating ir-hGRF and growth hormone responses demonstrated under different circumstances suggests that an important source of human growth hormone releasing factor lies outside the hypothalamus and that secretion from this source is unconnected with the normal control of pituitary growth hormone secretion.

Stimulation of Human-Growth-Hormone Secretion by L-Dopa

1970 ◽  
Vol 283 (26) ◽  
pp. 1425-1429 ◽  
Author(s):  
A. E. Boyd ◽  
Harold E. Lebovitz ◽  
John B. Pfeiffer
Keyword(s):  
Growth Hormone ◽  
Human Growth Hormone ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Human Growth ◽  
Stimulation Of

The regulation of insulin-induced and sleep-related human growth hormone secretion: A review

1979 ◽  
Vol 4 (4) ◽  
pp. 341-349 ◽  
Author(s):  
Wallace B. Mendelson ◽  
Laurence S. Jacobs ◽  
J.Christian Gillin ◽  
Richard Jed Wyatt
Keyword(s):  
Growth Hormone ◽  
Human Growth Hormone ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Human Growth
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