On the involvement of a glucose 6-phosphate transport system in the function of microsomal glucose 6-phosphatase

1975 ◽  
Vol 6 (2) ◽  
pp. 75-83 ◽  
Author(s):  
William J. Arion ◽  
Bruce K. Wallin ◽  
Alex J. Lange ◽  
Lawrence M. Ballas
Keyword(s):  
Transport System ◽  
Phosphate Transport

Establishment of a Parathyroid Hormone-Responsive Phosphate Transport System in Vitro Using Cultured Renal Cells*

Endocrinology ◽  
1986 ◽  
Vol 119 (5) ◽  
pp. 1954-1963 ◽  
Author(s):  
YOSHIKAZU KINOSHITA ◽  
MASAAKI FUKASE ◽  
AKIMITSU MIYAUCHI ◽  
MUTSUMI TAKENAKA ◽  
MASAKI NAKADA ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Transport System ◽  
Phosphate Transport ◽  
Renal Cells

Phosphate uptake by renal membrane vesicles of rabbits adapted to high and low phosphorus diets

1983 ◽  
Vol 245 (2) ◽  
pp. F175-F180 ◽  
Author(s):  
L. Cheng ◽  
C. T. Liang ◽  
B. Sacktor
Keyword(s):  
Transport System ◽  
Phosphate Uptake ◽  
Membrane Vesicles ◽  
Phosphate Transport ◽  
Uptake System ◽  
Low Phosphorus ◽  
Dietary Phosphate ◽  
Preferred Species ◽  
Uptake Medium ◽  
Phosphate Carrier

Renal adaptation to changes in phosphate intake was studied by comparing phosphate uptake by proximal tubule brush border membrane vesicles from rabbits on a relatively high or low phosphorus diet. The low phosphorus diet increased Na+ gradient-dependent phosphate uptake. Uptake in the absence of Na+ and in the presence of Na+, but no gradient, was not significantly affected. The phosphorus diet did not alter Na+ gradient-dependent D-glucose and L-proline uptake. The low phosphorus diet increased Vmax; affinity for phosphate was not appreciably changed. At all concentrations of extravesicular Na+, phosphate uptake was higher in membrane vesicles from animals fed the low phosphorus diet; the kinetics of the phosphate uptake system, with respect to Na+, was also altered by the change in dietary phosphate. These findings suggest that adaptation involves an alteration in the rate of translocation of the Na+-phosphate carrier when energized by a Na+ gradient driving force rather than a change in the number of Na+-phosphate carrier sites. With membrane vesicles from rabbits fed a low phosphorus diet, phosphate uptake increased several-fold when the pH of the uptake medium was raised, whereas with membrane vesicles from animals fed a high phosphorus diet the enhancement of uptake with alkalinization was relatively small. Irrespective of the diet, divalent phosphate was the probable preferred species for transport. Dietary adaptation was associated, however, with an alteration in the pH dependency of the transport system per se. These findings provide evidence that the adaptation of the kidney phosphate transport system to dietary phosphate load involves an intrinsic change in the Na+-phosphate carrier.

scholarly journals The Protein Component(s) of the Isolated Phosphate-Transport System of Mitochondria

2005 ◽  
Vol 128 (1) ◽  
pp. 97-105 ◽  
Author(s):  
Hanno V. J. KOLBE ◽  
Peter MENDE ◽  
Bernhard KADENBACH
Keyword(s):  
Transport System ◽  
Phosphate Transport ◽  
Protein Component

scholarly journals Isolation and reconstruction of the phosphate-transport system from pig heart mitochondria

FEBS Letters ◽  
1981 ◽  
Vol 124 (2) ◽  
pp. 265-269 ◽  
Author(s):  
H.V.J. Kolbe ◽  
J. Böttrich ◽  
G. Genchi ◽  
F. Palmieri ◽  
B. Kadenbach
Keyword(s):  
Transport System ◽  
Phosphate Transport ◽  
Heart Mitochondria

Growth of Escherichia coli on glucosamine 6-phosphate: selection of a constitutive hexose phosphate transport system mutant

1978 ◽  
Vol 24 (3) ◽  
pp. 203-208
Author(s):  
George W. Dietz Jr.
Keyword(s):  
Escherichia Coli ◽  
Transport System ◽  
Phosphate Transport ◽  
Wild Type ◽  
Hexose Phosphate ◽  
Selection Of

Glucosamine 6-phosphate was found to be a substrate but not an inducer for the hexose phosphate transport system of Escherichia coli. Wild-type cells grow very poorly on glucosamine 6-phosphate. A mutant was selected that will grow rapidly on glucosamine 6-phosphate because it contains a constitutive hexose phosphate transport system.

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