Vinyl chloride-induced hepatic coproporphyrinuria with transition to chronic hepatic porphyria

1984 ◽  
Vol 62 (4) ◽  
pp. 175-178 ◽  
Author(s):  
M. Doss ◽  
C. -E. Lange ◽  
G. Veltman
Author(s):  
I. V. Kudaeva ◽  
O. A. Dyakovich ◽  
I. M. Eshchina

It was found that in persons exposed by vinyl chloride, the risk of hypertension increases six times in carriers of the genotype C/C polymorphic variant of Leu28Pro gene APO E, 9.5 times - in carriers of the genotype T/T polymorphic variant C786T gene eNOS3 and 1.75 times - in carriers of the genotype T/C polymorphic variant Met 235 Thr gene AGT.


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